Différenciation in vitro de cartilage à partir des crêtes neurales céphaliques chez Pleurodeles waltlii Michah.

Development ◽  
1975 ◽  
Vol 33 (2) ◽  
pp. 335-342
Author(s):  
Par Jacqueline Corsin
Keyword(s):  
Environmental Factors ◽  
Neural Crest ◽  
Neural Crest Cells ◽  
In Vitro Differentiation ◽  
Dorsal Mesoderm ◽  
Pleurodeles Waltlii ◽  
Cellular Components ◽  
Foregut Endoderm

In vitro differentiation of cartilage from cephalic neural crest of Pleurodeles waltlii Michah. Parts of cephalic neural crest of Pleurodeles waltlii have been cultivated in vitro alone or in explants containing other cellular components. It was hoped that these experiments would establish under what conditions cephalic neural crest cells can differentiate into chondroblasts. It has been demonstrated that this differentiation is possible only under the influence of the dorsal mesoderm and foregut endoderm. It appears that neural crest cells are relatively pluripotent and progressively differentiate in response to local environmental factors.

In vitro differentiation of quail neural crest cells into sensory-like neuroblasts

1988 ◽  
Vol 39 (1) ◽  
pp. 69-83 ◽  
Author(s):  
Maya Sieber-Blum ◽  
Sanjiv R. Kumar ◽  
Danny A. Riley
Keyword(s):  
Neural Crest ◽  
Neural Crest Cells ◽  
In Vitro Differentiation

Epidermal Growth Factor (EGF) Promotes the In Vitro Differentiation of Neural Crest Cells to Neurons and Melanocytes

2009 ◽  
Vol 29 (8) ◽  
pp. 1087-1091 ◽  
Author(s):  
Ricardo Castilho Garcez ◽  
Bianca Luise Teixeira ◽  
Suelen dos Santos Schmitt ◽  
Márcio Alvarez-Silva ◽  
Andréa Gonçalves Trentin
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Neural Crest ◽  
Neural Crest Cells ◽  
In Vitro Differentiation ◽  
Epidermal Growth

Induction of melanocyte precursors from neural crest cells surrounding the neural tube-like structures developed in vitro using mouse ES cell culture

2007 ◽  
Vol 27 (1) ◽  
pp. 45-52
Author(s):  
Koh-ichi Atoh ◽  
Manae S. Kurokawa ◽  
Hideshi Yoshikawa ◽  
Chieko Masuda ◽  
Erika Takada ◽  
...  
Keyword(s):  
Cell Culture ◽  
Neural Crest ◽  
Neural Tube ◽  
Neural Crest Cells ◽  
Es Cell ◽  
Mouse Es Cell

Cellular fibronectin promotes adrenergic differentiation of quail neural crest cells in vitro

1981 ◽  
Vol 133 (2) ◽  
pp. 285-295 ◽  
Author(s):  
Maya Sieber-Blum ◽  
Fritz Sieber ◽  
Kenneth M. Yamada
Keyword(s):  
Neural Crest ◽  
Neural Crest Cells ◽  
Cellular Fibronectin

scholarly journals Lineage-specific requirements of β-catenin in neural crest development

2002 ◽  
Vol 159 (5) ◽  
pp. 867-880 ◽  
Author(s):  
Lisette Hari ◽  
Véronique Brault ◽  
Maurice Kléber ◽  
Hye-Youn Lee ◽  
Fabian Ille ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Neural Crest ◽  
Neural Crest Cells ◽  
Neural Crest Stem Cells ◽  
Downstream Signaling ◽  
Neural Crest Development ◽  
Sensory Neurogenesis

β-Catenin plays a pivotal role in cadherin-mediated cell adhesion. Moreover, it is a downstream signaling component of Wnt that controls multiple developmental processes such as cell proliferation, apoptosis, and fate decisions. To study the role of β-catenin in neural crest development, we used the Cre/loxP system to ablate β-catenin specifically in neural crest stem cells. Although several neural crest–derived structures develop normally, mutant animals lack melanocytes and dorsal root ganglia (DRG). In vivo and in vitro analyses revealed that mutant neural crest cells emigrate but fail to generate an early wave of sensory neurogenesis that is normally marked by the transcription factor neurogenin (ngn) 2. This indicates a role of β-catenin in premigratory or early migratory neural crest and points to heterogeneity of neural crest cells at the earliest stages of crest development. In addition, migratory neural crest cells lateral to the neural tube do not aggregate to form DRG and are unable to produce a later wave of sensory neurogenesis usually marked by the transcription factor ngn1. We propose that the requirement of β-catenin for the specification of melanocytes and sensory neuronal lineages reflects roles of β-catenin both in Wnt signaling and in mediating cell–cell interactions.

Evidence for collapsin-1 functioning in the control of neural crest migration in both trunk and hindbrain regions

Development ◽  
1999 ◽  
Vol 126 (10) ◽  
pp. 2181-2189 ◽  
Author(s):  
B.J. Eickholt ◽  
S.L. Mackenzie ◽  
A. Graham ◽  
F.S. Walsh ◽  
P. Doherty
Keyword(s):  
Cell Migration ◽  
Neural Crest ◽  
Neural Crest Cell ◽  
Axon Growth ◽  
Neural Crest Cells ◽  
Neural Crest Cell Migration ◽  
Neural Crest Migration ◽  
Migration Pathways ◽  
Crest Cell

Collapsin-1 belongs to the Semaphorin family of molecules, several members of which have been implicated in the co-ordination of axon growth and guidance. Collapsin-1 can function as a selective chemorepellent for sensory neurons, however, its early expression within the somites and the cranial neural tube (Shepherd, I., Luo, Y., Raper, J. A. and Chang, S. (1996) Dev. Biol. 173, 185–199) suggest that it might contribute to the control of additional developmental processes in the chick. We now report a detailed study on the expression of collapsin-1 as well as on the distribution of collapsin-1-binding sites in regions where neural crest cell migration occurs. collapsin-1 expression is detected in regions bordering neural crest migration pathways in both the trunk and hindbrain regions and a receptor for collapsin-1, neuropilin-1, is expressed by migrating crest cells derived from both regions. When added to crest cells in vitro, a collapsin-1-Fc chimeric protein induces morphological changes similar to those seen in neuronal growth cones. In order to test the function of collapsin-1 on the migration of neural crest cells, an in vitro assay was used in which collapsin-1-Fc was immobilised in alternating stripes consisting of collapsin-Fc/fibronectin versus fibronectin alone. Explanted neural crest cells derived from both trunk and hindbrain regions avoided the collapsin-Fc-containing substratum. These results suggest that collapsin-1 signalling can contribute to the patterning of neural crest cell migration in the developing chick.

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