scholarly journals Twin methodology in epigenetic studies

2015 ◽  
Vol 218 (1) ◽  
pp. 134-139 ◽  
Author(s):  
Q. Tan ◽  
L. Christiansen ◽  
J. von Bornemann Hjelmborg ◽  
K. Christensen
Keyword(s):  
2014 ◽  
Vol 26 ◽  
pp. 1-10 ◽  
Author(s):  
Örjan Sandewall ◽  
David Cesarini ◽  
Magnus Johannesson

Author(s):  
Harold Snieder ◽  
Alex J MacGregor
Keyword(s):  

Sensors ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 5013
Author(s):  
Haochen Liu ◽  
Lawrence Tinsley ◽  
Wayne Lam ◽  
Sri Addepalli ◽  
Xiaochen Liu ◽  
...  

Unverified or counterfeited electronic components pose a big threat globally because they could lead to malfunction of safety-critical systems and reduced reliability of high-hazard assets. The current inspection techniques are either expensive or slow, which becomes the bottleneck of large volume inspection. As a complement of the existing inspection capabilities, a pulsed thermography-based screening technique is proposed in this paper using a digital twin methodology. A FEM-based simulation unit is initially developed to simulate the internal structure of electronic components with deviations of multiple physical properties, informed by X-ray data, along with its thermal behaviour under exposure to instantaneous heat. A dedicated physical inspection unit is then integrated to verify the simulation unit and further improve the simulation by taking account of various uncertainties caused by equipment and samples. Principle component analysis is used for feature extraction, and then a set of machine learning-based classifiers are employed for quantitative classification. Evaluation results of 17 chips from different sources successfully demonstrate the effectiveness of the proposed technique.


Author(s):  
Bartosz Skobiej ◽  
Arto Niemi

AbstractThis article discusses the aspect of modeling weather conditions in marine environment for implementation in the offshore wind farm domain. It is clear that harsh sea weather conditions influence many characteristics of any offshore installation. The accessibility to the infrastructure, maintenance procedures, failure ratios of components, energy provision levels, or utilization of vessels—are the examples of weather-related issues connected to the offshore wind industry. Regarding the growing popularity of digital twin methodology, authors present a novel view to generate weather data with copula-based method. The results obtained are compared to selected historical data and implemented into the maintenance model. The selected indicators of maintenance service are used for usability assessment of proposed copula-based method.


2020 ◽  
Vol 52 (4) ◽  
pp. 112-118
Author(s):  
STANISLAV E. DRAGUNOV ◽  
◽  
SVETLANA S. POPOVA ◽  
ANNA VLADIMIROVNA MATOKHINA ◽  
MAXIM A. CHERNETSKY ◽  
...  

This article discusses the approbation of the digital twin methodology for condition monitoring and operation control within the framework of the lease, the Rejoint exoskeletal trainer used to restore muscle activity after injuries and strokes. To test the work, digital shadow technology is used, which makes it possible to obtain information about the state of the device in remote operation, which improves the quality. maintenance and increase the life of the device. The monitoring process includes the installation of additional sensors on the device, which allow collecting realtime data on the position of the nodes and the state of the device, transmitting data to the server for subsequent analysis. The obtained data allow carrying out, in addition to digital analytics, computer simulations, providing for analysis a digital copy of the actually operated device.


BMJ ◽  
1996 ◽  
Vol 313 (7055) ◽  
pp. 491-491 ◽  
Author(s):  
K. O. Kyvik
Keyword(s):  

Author(s):  
Harold Snieder ◽  
Xiaoling Wang ◽  
Alex J MacGregor
Keyword(s):  

1979 ◽  
Vol 28 (1) ◽  
pp. 35-40 ◽  
Author(s):  
Joe C. Christian

Twin methodology for the analysis of continuously distributed traits is presented as a guideline for initial steps in the analysis of twin data. Tests for heterogeneity of twin means and variances are reviewed along with estimates of genetic variance.Analysis of twin data appears on the surface to be a rather simple task, but investigators may well be confused by the wealth of choices available for hypothesis testing. This paper is designed to help the less experienced investigator, with perhaps a modest amount of data, begin analysis with maximum attention to testing all testable assumptions of the twin model, and using recent examples of applications of the methods.


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