Biomechanical Compatibility of Cruciate Ligament Prostheses
An experiment was performed to determine the effects of stiffness of cruciate ligament prostheses upon joint function and degeneration. Twenty four sheep were allocated into four groups. One group had the ligament excised with no replacement and subsequent groups underwent substitution procedures with either a stiff, matched, or lax prosthesis. After six months the animals with a stiff or matched prosthesis were significantly less lame than those with a lax prosthesis or no prosthesis. However, at post mortem examination the animals with a stiff prosthesis or no prosthesis showed significantly more widespread cartilage damage than the matched or lax groups. The results indicate that either a stiff or matched prosthesis may restore functional activity, but that the stiff prosthesis may predispose to increased degenerative changes.