scholarly journals Species differences in absorption, metabolism and excretion of pranoprofen, a 2-arylpropionic acid derivative, in experimental animals.

1990 ◽  
Vol 13 (12) ◽  
pp. 739-744 ◽  
Author(s):  
Noriyuki ARIMA ◽  
Yasuyuki KATO
Keyword(s):  
Acid Derivative ◽  
Species Differences ◽  
Experimental Animals ◽  
Arylpropionic Acid

scholarly journals Characterization of Species Differences in Xenobiotic Metabolism in Non-experimental Animals

2017 ◽  
Vol 137 (3) ◽  
pp. 257-263
Author(s):  
Hazuki Mizukawa ◽  
Yoshinori Ikenaka ◽  
Mayu Kakehi ◽  
Shouta Nakayama ◽  
Mayumi Ishizuka
Keyword(s):  
Species Differences ◽  
Xenobiotic Metabolism ◽  
Experimental Animals

Analytical Electron Microscopy (AEM) of Meningeal Cells Exposed to Particulate Cobalt During Studies of Experimental Epilepsy

1982 ◽  
Vol 40 ◽  
pp. 186-187
Author(s):  
R.G. Frederickson ◽  
R.G. Ulrich ◽  
J.L. Culberson
Keyword(s):  
Electron Microscopy ◽  
Analytical Electron Microscopy ◽  
Experimental Epilepsy ◽  
Metallic Cobalt ◽  
Experimental Animals ◽  
X Ray ◽  
Brain Surface ◽  
Meningeal Cells ◽  
Analytical Electron ◽  
The Brain

Metallic cobalt acts as an epileptogenic agent when placed on the brain surface of some experimental animals. The mechanism by which this substance produces abnormal neuronal discharge is unknown. One potentially useful approach to this problem is to study the cellular and extracellular distribution of elemental cobalt in the meninges and adjacent cerebral cortex. Since it is possible to demonstrate the morphological localization and distribution of heavy metals, such as cobalt, by correlative x-ray analysis and electron microscopy (i.e., by AEM), we are using AEM to locate and identify elemental cobalt in phagocytic meningeal cells of young 80-day postnatal opossums following a subdural injection of cobalt particles.

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