scholarly journals Studies on Azulenes. VII. Oxidation of Hydroazulenes with Selenium Dioxide.

1957 ◽  
Vol 5 (5) ◽  
pp. 426-430 ◽  
Author(s):  
Hiroshi Watanabe
Keyword(s):  
Selenium Dioxide

Substituted 4-Formyl-2H-chromen-2-ones: Their Reaction with N-(2,3,4,6-Tetra-Oacetyl- β-D-galactopyranosyl)thiosemicarbazide, Antibacterial and Antifungal Activity of Their Thiosemicarbazone Products

2020 ◽  
Vol 24 (19) ◽  
pp. 2272-2282
Author(s):  
Vu Ngoc Toan ◽  
Nguyen Minh Tri ◽  
Nguyen Dinh Thanh
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Selenium Dioxide ◽  
Antibacterial And Antifungal Activity ◽  
E Coli ◽  
Antibacterial And Antifungal Activities ◽  
Alkyl Ethers ◽  
Antibacterial And Antifungal

Several 6- and 7-alkoxy-2-oxo-2H-chromene-4-carbaldehydes were prepared from corresponding alkyl ethers of 6- and 7-hydroxy-4-methyl-2-oxo-2H-chromen-2-ones by oxidation using selenium dioxide. 6- and 7-Alkoxy-4-methyl-2H-chromenes were obtained with yields of 57-85%. Corresponding 4-carbaldehyde derivatives were prepared with yields of 41-67%. Thiosemicarbazones of these aldehydes with D-galactose moiety were synthesized by reaction of these aldehydes with N-(2,3,4,6-tetra-O-acetyl-β-Dgalactopyranosyl) thiosemicarbazide with yields of 62-74%. These thiosemicarbazones were screened for their antibacterial and antifungal activities in vitro against bacteria, such as Staphylococcus aureus, Escherichia coli, and fungi, such as Aspergillus niger, Candida albicans. Several compounds exhibited strong inhibitory activity with MIC values of 0.78- 1.56 μM, including 8a (against S. aureus, E. coli, and C. albicans), 8d (against E. coli and A. niger), 9a (against S. aureus), and 9c (against S. aureus and C. albicans).

scholarly journals 7-Bromo-[1,2,5]selenadiazolo[3,4-d]pyridazin-4(5H)-one

Molbank ◽  
10.3390/m1229 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1229
Author(s):  
Timofey N. Chmovzh ◽  
Oleg A. Rakitin
Keyword(s):  
Mass Spectrometry ◽  
Heterocyclic System ◽  
High Resolution Mass Spectrometry ◽  
Uv Spectroscopy ◽  
Hydrolysis Product ◽  
Selenium Dioxide ◽  
Biologically Active ◽  
Photovoltaic Materials ◽  
Organic Photovoltaic Materials ◽  
Ir And Uv Spectroscopy

New heterocyclic systems containing 1,2,5-chalcogenadiazoles are of great interest for the creation of organic photovoltaic materials and biologically active compounds. In this communication, 3,6-dibromopyridazine-4,5-diamine was investigated in reaction with selenium dioxide in order to obtain 4,7-dibromo-[1,2,5]selenadiazolo[3,4-d]pyridazine. We found that 7-bromo-[1,2,5]selenadiazolo[3,4-d]pyridazin-4(5H)-one, the first representative of the new heterocyclic system, was isolated as a hydrolysis product of the corresponding 4,7-dibromoderivative. The structure of the newly synthesized compound was established by means of elemental analysis, high-resolution mass spectrometry, 1H, 13C NMR, IR and UV spectroscopy, and mass spectrometry.

ortho-Diquaternary aromatic compounds. II. Synthesis and spectral properties of β,β′-dihydroxy-2,3-di-t-butylnaphthalene and related crowded aromatics

1969 ◽  
Vol 47 (23) ◽  
pp. 4313-4318 ◽  
Author(s):  
L. R. C. Barclay ◽  
G. R. Nixon ◽  
H. M. Foote ◽  
S. L. Barclay
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Aromatic Compounds ◽  
Spectral Properties ◽  
Bond Angle ◽  
Chemical Shifts ◽  
Dimethyl Ester ◽  
Selenium Dioxide ◽  
Hydride Reduction ◽  
Cyclic Compounds ◽  
Compression Effects

Cyclialkylation of naphthalene with 2,2,5,5-tetramethyltetrahydrofuranone yielded 2-keto-1,1,4,4-tetramethyl-1,2,3,4-tetrahydroanthracene (1). Selenium dioxide oxidation of 1 yielded the corresponding diketone (3) and periodate cleavage of 3 yielded 2,3-naphthalene-diisobutyric acid (4). Hydride reduction of the dimethyl ester (6) of 4 yielded the diol, β,β′-dihydroxy-2,3-di-t-butylnaphthalene (7). The relative chemical shifts of aromatic protons of 1,2,4,5-tetraalkylbenzenes containing gem dimethyls are rationalized in terms of compression effects exerted by the bulky ortho groups. Nuclear magnetic resonance and ultraviolet spectral results for the ortho di-t-butyl aromatic derivatives 4, 6, and 7 are compared to the model cyclic compounds 1 and anhydride (5) of 4 in terms of the strain caused by bond angle deformations in the side chains.

Selenium dioxide entry into 3-acylindoles

1979 ◽  
Vol 20 (12) ◽  
pp. 1025-1028 ◽  
Author(s):  
Olivia Campos ◽  
James M. Cook
Keyword(s):  
Selenium Dioxide
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