The Effects of Activity-Wheel Running After β-Adrenoreceptor Blockade on Copulatory Behavior and Galanin mRNA in the Medial Preoptic Area and Locus Coeruleus in Male Rats

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S523
Author(s):  
Nathaniel J. Thom ◽  
Rod K. Dishman ◽  
Philip Holmes ◽  
Jenny Reiss ◽  
Sarah Eisenstein
1986 ◽  
Vol 3 (4) ◽  
pp. 311-320 ◽  
Author(s):  
Tsuyoshi Horio ◽  
Tsuyoshi Shimura ◽  
Momozo Hanada ◽  
Minoru Shimokochi

2000 ◽  
Vol 38 (2) ◽  
pp. 86-93 ◽  
Author(s):  
Andrew N. Clancy ◽  
Doris Zumpe ◽  
Richard P. Michael

1998 ◽  
Vol 274 (1) ◽  
pp. R243-R247 ◽  
Author(s):  
Yoshikazu Sato ◽  
Hiroki Horita ◽  
Toshie Kurohata ◽  
Hideki Adachi ◽  
Taiji Tsukamoto

We investigated the influence of the extracellular nitric oxide (NO) level on male copulatory behavior. We confirmed the changes of nitrite ([Formula: see text]) and nitrate ([Formula: see text]) in the medial preoptic area (MPOA) by administration of the NO precursorl-arginine (l-Arg, 10 mM) or the NO synthase inhibitor N G-monomethyl-l-arginine (l-NMMA, 10 mM) via a dialysis probe. [Formula: see text] and[Formula: see text] were measured simultaneously by an in vivo microdialysis method coupled with the Griess reaction.l-Arg induced significant elevations of extracellular [Formula: see text]and [Formula: see text].l-NMMA significantly reduced[Formula: see text] and[Formula: see text] levels. We observed male copulatory behavior during infusion ofl-Arg orl-NMMA. The mount rate of male rats significantly increased during infusion ofl-Arg in the MPOA. Administration of l-NMMA reduced the mount rate. These findings suggested that the elevation of extracellular NO in the MPOA facilitates male copulatory behavior of rats, whereas the decrease of NO reduces their copulatory behavior.


Sign in / Sign up

Export Citation Format

Share Document