Effect Of Neuromuscular Electrical Stimulation With Blood Flow Restriction On Muscle Size And Strength

2015 ◽  
Vol 47 ◽  
pp. 536
Author(s):  
Hayao Ozaki ◽  
Toshiharu Natsume ◽  
Takashi Abe ◽  
Shuichi Machida ◽  
Hisashi Naito
Keyword(s):  
Blood Flow ◽  
Electrical Stimulation ◽  
Neuromuscular Electrical Stimulation ◽  
Blood Flow Restriction ◽  
Muscle Size ◽  
Flow Restriction

scholarly journals Effects of combined treatment with blood flow restriction and low-current electrical stimulation on muscle hypertrophy in rats

2019 ◽  
Vol 127 (5) ◽  
pp. 1288-1296
Author(s):  
Madoka Yoshikawa ◽  
Takeshi Morifuji ◽  
Tomohiro Matsumoto ◽  
Noriaki Maeshige ◽  
Minoru Tanaka ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Blood Flow ◽  
Electrical Stimulation ◽  
Muscle Hypertrophy ◽  
Combined Treatment ◽  
Blood Flow Restriction ◽  
Sectional Area ◽  
Cross Sectional ◽  
Flow Restriction ◽  
Skeletal Muscle Hypertrophy

This study aimed to clarify the effects of a combined treatment comprising blood flow restriction and low-current electrical stimulation on skeletal muscle hypertrophy in rats. Male Wistar rats were divided into control (Cont), blood flow restriction (Bfr), electrical stimulation (Es), or Bfr with Es (Bfr + Es) groups. Pressure cuffs (80 mmHg) were placed around the thighs of Bfr and Bfr + Es rats. Low-current Es was applied to calf muscles in the Es and Bfr + Es rats. In experiment 1, a 1-day treatment regimen (5-min stimulation, followed by 5-min rest) was delivered four times to study the acute effects. In experiment 2, the same treatment regimen was delivered three times/wk for 8 wk. Body weight, muscle mass, changes in maximal isometric contraction, fiber cross-sectional area of the soleus muscle, expression of phosphorylated and total-ERK1/2, phosphorylated-rpS6 Ser235/236, phosphorylated and total Akt, and phosphorylated-rpS6 Ser240/244 were measured. Bfr and Es treatment alone failed to induce muscle hypertrophy and increase the expression of phosphorylated rpS6 Ser240/244. Combined Bfr + Es upregulated muscle mass, increased the fiber cross-sectional area, and increased phosphorylated rpS6 Ser240/244 expression and phosphorylated rpS6 Ser235/236 expression compared with controls. Combined treatment with Bfr and low-current Es can induce muscle hypertrophy via activation of two protein synthesis signaling pathways. This treatment should be introduced for older patients with sarcopenia and others with muscle weakness. NEW & NOTEWORTHY We investigated the acute and chronic effect of low-current electrical stimulation with blood flow restriction on skeletal muscle hypertrophy and the mechanisms controlling the hypertrophic response. Low-current electrical stimulation could not induce skeletal muscle hypertrophy, but a combination treatment did. Blood lactate and growth hormone levels were increased in the early response. Moreover, activation of ERK1/2 and mTOR pathways were observed in both the acute and chronic response, which contribute to muscle hypertrophy.

scholarly journals Effects of Low-Load, Elastic Band Resistance Training Combined With Blood Flow Restriction on Muscle Size and Arterial Stiffness in Older Adults

2014 ◽  
Vol 70 (8) ◽  
pp. 950-958 ◽  
Author(s):  
Tomohiro Yasuda ◽  
Kazuya Fukumura ◽  
Yusuke Uchida ◽  
Hitomi Koshi ◽  
Haruko Iida ◽  
...  
Keyword(s):  
Older Adults ◽  
Blood Flow ◽  
Resistance Training ◽  
Arterial Stiffness ◽  
Blood Flow Restriction ◽  
Muscle Size ◽  
Elastic Band ◽  
Flow Restriction ◽  
Low Load
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