Relationship Of The Daily Sleepiness Epworth Scale With The Grip Strength In Elderly With Parkinson’S Disease.

Background: Hypokinetic dysarthria and dysphagia are known features of Parkinson’s disease; however, self-perception of their handicapping effects on emotional, physical, and functional aspects of quality of life over disease duration is less understood. Objective: 1) Based upon patient self-perception, to determine the relationship of the handicapping effects of dysphagia and dysphonia with time since diagnosis in individuals with Parkinson’s disease; 2)To determine if there is a relationship between voice and swallowing handicap throughout the course of Parkinson’s disease. Method: 277 subjects completed the Dysphagia Handicap Index and the Voice Handicap Index. Subjects were divided into three groups based on disease duration: 0–4 years, 5–9 years, and 10 + years. Results: Subjects in the longer duration group identified significantly greater perceptions of voice and swallowing handicap compared to the shorter duration groups. There was a significant positive correlation between the DHI and VHI. Conclusion: Self-perception of swallowing and voice handicap in Parkinson’s disease are associated with later stages of disease and progress in a linear fashion. Self-perception of voice and swallowing handicap parallel each other throughout disease progression in Parkinson’s disease. Individuals may be able to compensate for changes in voice and swallowing early while sensory perceptual feedback is intact. Results support early targeted questioning of patient self-perception of voice and swallowing handicap as identification of one problem indicates awareness of the other, thus creating an opportunity for early treatment and maintenance of swallowing and communication quality of life for as long as possible.

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Depression in Parkinson's disease: study of 60 cases

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2005000500009 ◽

2005 ◽

Vol 63 (3b) ◽

pp. 766-771 ◽

Cited By ~ 14

Author(s):

Roberto César Pereira do Prado ◽

Egberto Reis Barbosa

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Psychiatric Symptoms ◽

Depression Scale ◽

Hamilton Depression Scale ◽

Structured Interviews ◽

Clinical Criteria ◽

Disease Study ◽

Age Range ◽

Relationship Of

Depression is very frequent in Parkinson’s disease (PD) and largely unrecognized by neurologists, emphasizing the need of an approach to psychiatric symptoms by non psychiatrists in order to ensure an early diagnosis of depression in PD; clinical characteristics and the prevalence rate of depression in PD were evaluated and the relationship of depression in PD with other variables were determined. Sixty PD subjects, who fulfilled the clinical criteria for primary PD, 56,6% males, age range from 44 to 85 years old, in different stages of the disease were investigated. All subjects were submitted to the UPDRS-III, V and VI, Clinical Interview Schedule and the Hamilton depression scale. A significant correlation was found between depression and UPDRS-III, V and VI, anxiety and irritability. The frequency of depression in PD in this study was nearly 40% possessing specific features. Structured interviews and evaluation scales are essential for an accurate diagnosis and proper treatment of depression in PD.

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Haplotype Analysis on the Relationship of the DNAJC6 Gene with Early-Onset Parkinson’s Disease Risk in a Chinese Population

Journal of Parkinson s Disease ◽

10.3233/jpd-181411 ◽

2019 ◽

Vol 9 (1) ◽

pp. 109-120

Author(s):

Ting Shen ◽

Shuai Zhao ◽

Yasi Jiang ◽

Jiali Pu ◽

Hsin-Yi Lai ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Early Onset ◽

Chinese Population ◽

Haplotype Analysis ◽

Disease Risk ◽

Relationship Of ◽

The Relationship ◽

Early Onset Parkinson’S Disease

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Concentration-effect relationship of levodopa in patients with Parkinson's disease after oral administration of an immediate release and a controlled release formulation.

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.1995.tb04407.x ◽

1995 ◽

Vol 39 (1) ◽

pp. 39-44 ◽

Cited By ~ 10

Author(s):

S Harder ◽

H Baas ◽

N Bergemann ◽

L Demisch ◽

S Rietbrock

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Controlled Release ◽

Oral Administration ◽

Immediate Release ◽

Concentration Effect ◽

Release Formulation ◽

Effect Relationship ◽

Controlled Release Formulation ◽

Relationship Of

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Frequency of non-motor symptoms in Peruvian patients with Parkinson's disease

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20130005 ◽

2013 ◽

Vol 71 (4) ◽

pp. 216-219 ◽

Cited By ~ 14

Author(s):

Carlos Cosentino ◽

Yesenia Nuñez ◽

Luis Torres

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Progressive Increase ◽

Motor Symptoms ◽

Number Of Patients ◽

Progression Of Disease ◽

The Mean ◽

Relationship Of ◽

The Relationship ◽

Non Motor Symptoms

Introduction: Non-motor symptoms in Parkinson's disease are often not well recognized in clinical practice. Non-motor symptoms questionnaire (NMSQuest) is a simple instrument that allows patients or caregivers to report non-motor symptoms in a practical manner. Objective: We attempted to determine the prevalence of non-motor symptoms in three hundred Parkinson's disease outpatients. Results: The mean total non-motor symptoms was 12.41, ranging from 0 to 27 of a maximum of 30. At least one was present in 99.3% of patients. A progressive increase in mean total score was observed across each 5-year interval. Depression domain scored the most “positive” answers while urinary and anxiety /memory were secondly and thirdly most prevalent respectively. Conclusion: The large number of patients included in this study allowed evaluation of the occurrence of non-motor symptoms in early and advanced disease in addition to the relationship of these kinds of symptoms with progression of disease.

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