Skeletal Muscle Force Production and Bioenergetics During All-out Exercise

2017 ◽  
Vol 49 (5S) ◽  
pp. 903
Author(s):  
Ryan M. Broxterman ◽  
Gwenael Layec ◽  
Thomas J. Hureau ◽  
David E. Morgan ◽  
Amber D. Bledsoe ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Force ◽  
Force Production ◽  
Muscle Force Production

Beetroot Juice Increases Skeletal Muscle Force Production in Recreationally Active Subjects.

2016 ◽  
Vol 48 ◽  
pp. 897
Author(s):  
Jamie Whitfield ◽  
George J. F. Heigenhauser ◽  
Lawrence L. Spriet ◽  
Graham P. Holloway ◽  
A. Russell Tupling
Keyword(s):  
Skeletal Muscle ◽  
Muscle Force ◽  
Force Production ◽  
Beetroot Juice ◽  
Muscle Force Production

scholarly journals Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle

eLife ◽  
2019 ◽  
Vol 8 ◽  
Author(s):  
Antonio Michelucci ◽  
Simona Boncompagni ◽  
Laura Pietrangelo ◽  
Maricela García-Castañeda ◽  
Takahiro Takano ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Time Course ◽  
Acute Exercise ◽  
Muscle Force ◽  
Contractile Function ◽  
Force Production ◽  
High Frequency Stimulation ◽  
Frequency Stimulation ◽  
Muscle Force Production ◽  
Muscle Contractile

Exercise promotes the formation of intracellular junctions in skeletal muscle between stacks of sarcoplasmic reticulum (SR) cisternae and extensions of transverse-tubules (TT) that increase co-localization of proteins required for store-operated Ca2+ entry (SOCE). Here, we report that SOCE, peak Ca2+ transient amplitude and muscle force production during repetitive stimulation are increased after exercise in parallel with the time course of TT association with SR-stacks. Unexpectedly, exercise also activated constitutive Ca2+ entry coincident with a modest decrease in total releasable Ca2+ store content. Importantly, this decrease in releasable Ca2+ store content observed after exercise was reversed by repetitive high-frequency stimulation, consistent with enhanced SOCE. The functional benefits of exercise on SOCE, constitutive Ca2+ entry and muscle force production were lost in mice with muscle-specific loss of Orai1 function. These results indicate that TT association with SR-stacks enhances Orai1-dependent SOCE to optimize Ca2+ dynamics and muscle contractile function during acute exercise.

scholarly journals Docetaxel does not impair skeletal muscle force production in a murine model of cancer chemotherapy

2017 ◽  
Vol 5 (11) ◽  
pp. e13261 ◽  
Author(s):  
Thomas Chaillou ◽  
Ashley McPeek ◽  
Johanna T. Lanner
Keyword(s):  
Skeletal Muscle ◽  
Cancer Chemotherapy ◽  
Murine Model ◽  
Muscle Force ◽  
Force Production ◽  
Muscle Force Production

Does Raising Morning Rectal Temperature to Evening Levels Offset the Diurnal Variation in Muscle Force Production?

2013 ◽  
Vol 30 (4) ◽  
pp. 486-501 ◽  
Author(s):  
Ben J. Edwards ◽  
Samuel A. Pullinger ◽  
Jonathan W. Kerry ◽  
William R. Robinson ◽  
Tom P. Reilly ◽  
...  
Keyword(s):  
Diurnal Variation ◽  
Rectal Temperature ◽  
Muscle Force ◽  
Force Production ◽  
Muscle Force Production
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