scholarly journals Chemogenetic inhibition of histaminergic neurons significantly decreased wakefulness during the dark periods in mice.

2021 ◽  
Vol 94 (0) ◽  
pp. 2-Y-G1-1
Author(s):  
Hiroshi Kuroyanagi ◽  
Masato Tanaka ◽  
Fumito Naganuma ◽  
Tadaho Nakamura ◽  
Nobuyuki Okamura
Keyword(s):  
Histaminergic Neurons

THE ULTRASTRUCTURE DEVELOPMENT OF RAT BRAIN HISTAMINERGIC NEURONS IN POSTNATAL ONTOGENESIS

2019 ◽  
Vol 21 (1) ◽  
pp. 50-54
Author(s):  
S. M. Zimatkin ◽  
◽  
A. V. Zaerko ◽  
К. M. Phedina ◽  
O. B. Ostrovskaya ◽  
...  
Keyword(s):  
Rat Brain ◽  
Postnatal Ontogenesis ◽  
Histaminergic Neurons

Intraocular hypothalamic transplants containing histaminergic neurons: Innervation of host iris and hippocampal cografts

1990 ◽  
Vol 108 (3) ◽  
pp. 189-197 ◽  
Author(s):  
Ann-Charlotte Granholm ◽  
Hanna Bergman ◽  
Ludmila Mackerlova ◽  
Anders Blomqvist
Keyword(s):  
Histaminergic Neurons

Excitotoxic lesions of histaminergic neurons by excitatory amino acid agonists in the rat brain

1997 ◽  
Vol 232 (3) ◽  
pp. 159-162 ◽  
Author(s):  
Kazuhiko Yanai ◽  
Xiao-Lan Zhao ◽  
Takehiko Watanabe
Keyword(s):  
Amino Acid ◽  
Rat Brain ◽  
Excitatory Amino Acid ◽  
Histaminergic Neurons

NUCLEOLI IN DEVELOPING HISTAMINERGIC NEURONS OF THE RAT BRAIN

2020 ◽  
pp. 7-13
Author(s):  
Сергей Михайлович Зиматкин ◽  
Анастасия Викторовна Заерко ◽  
Екатерина Михайловна Федина
Keyword(s):  
Rat Brain ◽  
Postnatal Development ◽  
Size Structure ◽  
Postnatal Ontogenesis ◽  
Hypothalamic Nucleus ◽  
Postnatal Ontogeny ◽  
Hypothalamic Region ◽  
Postnatal Maturation ◽  
Histaminergic Neurons ◽  
White Rats

Введение. Существуют ряд физиологических, экспериментальных и патологических условий, которые могут индуцировать изменения в размере, морфологии, местоположении и количестве ядрышек в соответствии с функциональной и метаболической активностью. Одним из таких условий является постнатальное развитие клеток, в том числе и нейронов. Цель - изучение особенностей структурно-функционального становления ядрышек гистаминергических нейронов мозга крысы в постнатальном онтогенезе. Материал и методы. Работа выполнена на беспородных белых крысах (12 особей) в возрасте 5, 20 и 45 сут постнатального онтогенеза. Изучали число и размеры ядрышек в ядрах гистаминергических нейронов в ядре E2 задней гипоталамической области мозга крыс с применением электронно-микроскопических и морфометрических методик, а также - непараметрической статистики. Результаты. У крыс от 5 до 45 сут постнатального развития уменьшается число и увеличиваются размеры ядрышек в ядре гистаминергических нейронов задней области гипоталамуса, а также происходит перемещение ядрышек от кариолеммы к центру ядра. По мере взросления животных в гистаминергических нейронах происходит постепенное преобразование относительно компактных ядрышек в ретикулярные, при этом увеличивается количество фибриллярного и гранулярного компонентов, а также возрастает число и уменьшаются размеры фибриллярных центров. Кроме того, наблюдается уменьшение облака мигрирующих субъединиц рибосом между ядрышком и кариолеммой, а также количества ассоциированного с ядрышком гетерохроматина. Выводы. В ядре E2 гипоталамуса крыс в возрасте от 5 до 45 сут постнатального онтогенеза значительно изменяются число, размеры, строение и топография ядрышек в ядрах гистаминергических нейронов. Introduction. There are a number of physiological, experimental, and pathological conditions that can induce changes in the size, morphology, location, and number of nucleoli in accordance with functional and metabolic activity. One of these conditions is the postnatal maturation of cells, including neurons. Objective - to assess the characteristics of structural and functional formation of histaminergic neurons nucleoli in rat brain during postnatal ontogeny. Material and methods. The work was performed on the offspring of outbred white rats (12 rats) on the 5th, 20th and 45th days of postnatal ontogenesis. Electron microscopic, morphometric and statistical methods were used to study the number and quantity of nucleoli in the nuclei of histaminergic neurons located in the E2 nucleus of posterior hypothalamic region of rat brain. Results. From the 5th to the 45th day of the rat postnatal development, there was a decrease in the number and increase in the size of the nucleoli in the nuclei of histaminergic neurons located in the posterior hypothalamic region, as well as their movement from the karyolemma to the center of the nucleus. As animals growed up, relatively compact nucleoli in the brain histaminergic neurons gradually transformed into reticular nucleoli, while the quantity of fibrillar and granular components increased, at the same time the quantity of fibrillar centers increased and the size of fibrillar centers decreased. In addition, we detected a decrease in the cloud of migrating ribosome subunits between the nucleolus and karyolemma and in the amount of heterochromatin associated with the nucleolus. Conclusions. From the 5th to the 45th day of the postnatal development, the number, size, structure and topography of the nucleoli of the rat brain histaminergic neurons located in the E2 hypothalamic nucleus in postnatal ontogenesis changed significantly.

Control of Central Histaminergic Neurons for Respiration during Hypercapnia in Conscious Mice

2007 ◽  
pp. 17-24
Author(s):  
Michiko Iwase ◽  
Masahiko Izumizaki ◽  
Kenichi Miyamoto ◽  
Mitsuko Kanamaru ◽  
Ikuo Homma
Keyword(s):  
Histaminergic Neurons

scholarly journals Effect of GABAergic agents on the histaminergic neurons in the mouse brain.

1985 ◽  
Vol 39 ◽  
pp. 232
Author(s):  
Masahiro Nishibori ◽  
Ryozo Oishi ◽  
Yoshinori Itoh ◽  
Kiyomi Saeki
Keyword(s):  
Mouse Brain ◽  
Histaminergic Neurons

Identification of histaminergic neurons in Aplysia

1990 ◽  
Vol 64 (3) ◽  
pp. 736-744 ◽  
Author(s):  
A. Elste ◽  
J. Koester ◽  
E. Shapiro ◽  
P. Panula ◽  
J. H. Schwartz
Keyword(s):  
Presynaptic Inhibition ◽  
Ganglion Cells ◽  
Lucifer Yellow ◽  
Cerebral Ganglion ◽  
Abdominal Ganglion ◽  
Serotonergic Neuron ◽  
Histaminergic Neurons ◽  
The Central Nervous System ◽  
Bag Cells ◽  
The Right

1. We have identified putative histaminergic neurons in the central nervous system of Aplysia californica by light-microscopic autoradiography after uptake of [3H]histamine and by immunohistochemistry with the use of an antibody specific for histamine. 2. In the cerebral ganglion cells previously shown to contain histamine (C2 and 2 large neighboring cells in the E cluster and a group of smaller cells in the L cluster) were identified both by uptake of [3H]histamine and by histamine immunoreactivity. The identification of C2 was confirmed by experiments in which individual C2s were characterized electrophysiologically and injected with Lucifer yellow before processing for immunohistochemistry. The giant serotonergic neuron did not take up [3H]histamine and was not immunoreactive. 3. In the abdominal ganglion two clusters of cells--one in the left hemiganglion and the other in the right--took up [3H]histamine and were histamine immunoreactive. These clusters are located in the regions occupied by the 30 identified respiratory interneurons, R25 and L25. Individual cells in the R25 and L25 clusters were identified electrophysiologically, marked by injection of Lucifer yellow, and processed for immunocytochemistry. Eleven of the 30 L25 cells examined (from 7 ganglia) and 2 of the 25 R25 cells (from 6 ganglia) that had been marked with Lucifer yellow were also histamine immunoreactive. 4. Also in the abdominal ganglion, identified cells in the L32 cluster were not histamine immunoreactive and did not take up [3H]histamine. These interneurons, which mediate presynaptic inhibition, had previously been considered histaminergic. Neurons in the ganglion known to use transmitters other than histamine (L10, R2, RB cells, and bag cells) were not histamine immunoreactive.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Thyrotropin-releasing hormone-containing axons innervate histaminergic neurons in the tuberomammillary nucleus

2012 ◽  
Vol 1488 ◽  
pp. 72-80 ◽  
Author(s):  
Anna Sárvári ◽  
Erzsébet Farkas ◽  
Andrea Kádár ◽  
Györgyi Zséli ◽  
Tamás Füzesi ◽  
...  
Keyword(s):  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Tuberomammillary Nucleus ◽  
Histaminergic Neurons

Characterization of Histaminergic H3 Receptors in Intraocular Tuberomammillary Transplants Containing Histaminergic Neurons

1995 ◽  
Vol 136 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Hanna Bergman ◽  
George D. Prell ◽  
Carl R. Lupica ◽  
Ann-Charlotte E. Granholm
Keyword(s):  
Histaminergic Neurons ◽  
H3 Receptors
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