Case of thymic parathyroid carcinoma in a haemodialysis patient: application of tumour chemosensitivity testing

2004 ◽  
Vol 118 (2) ◽  
pp. 162-164 ◽  
Author(s):  
I. A. Srouji ◽  
A. Resouly ◽  
I. A. Cree
Keyword(s):  
End Stage Renal Disease ◽  
Parathyroid Carcinoma ◽  
Haemodialysis Patient ◽  
Treatment Options ◽  
Rare Tumour ◽  
Tertiary Hyperparathyroidism ◽  
Stage Renal Disease ◽  
End Stage ◽  
Individual Tumour ◽  
Non Surgical Treatment

Parathyroid carcinoma is a rare tumour, which is often difficult to diagnose. This is especially true in patients with pre-existing tertiary hyperparathyroidism of end-stage renal disease. A case is presented of parathyroid carcinoma in a haemodialysis patient withunusual thymic involvement. After demonstrating the difficulty in pre-operative diagnosis and risk of recurrence, the importance of non-surgical treatment options is discussed and the investigation of individual tumour chemosensitivity is introduced, which is new to this type of cancer.

scholarly journals Secondary and Tertiary Hyperparathyroidism: A Narrative Review

2019 ◽  
Vol 109 (4) ◽  
pp. 271-278 ◽  
Author(s):  
W. Y. van der Plas ◽  
M. E. Noltes ◽  
T. M. van Ginhoven ◽  
S. Kruijff
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Phosphate Binders ◽  
Tertiary Hyperparathyroidism ◽  
Increased Risk ◽  
Vitamin D Supplements ◽  
The Individual ◽  
Stage Renal Disease ◽  
End Stage

End-stage renal disease is often complicated by the occurrence of secondary and eventually tertiary hyperparathyroidism, characterized by increased parathormone, calcium, and phosphate concentrations. Related symptoms include pruritus and osteodynia, concentration difficulties, and feelings of depression may be present. In the long-term, end-stage renal disease patients with hyperparathyroidism have an increased risk of all-cause and cardiovascular mortality. Among treatment options are vitamin D supplements, phosphate binders, calcimimetics, and surgical parathyroidectomy. Determining the optimal treatment for the individual patient is challenging for nephrologists and endocrine surgeons. This review resumes the pathogenesis of hyperparathyroidism, clinical presentation, required diagnostic work-up, and discusses indications for the available treatment options for patients with secondary and tertiary hyperparathyroidism.

Preferences of Nephrologists among End-Stage Renal Disease Treatment Options

1985 ◽  
Vol 5 (6) ◽  
pp. 470-475 ◽  
Author(s):  
Cindy Dunham ◽  
William D. Mattern ◽  
William C. McGaghie
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Disease Treatment ◽  
Stage Renal Disease ◽  
End Stage

Fulminant metastatic calcinosis with cutaneous necrosis in a child with end-stage renal disease and tertiary hyperparathyroidism

1996 ◽  
Vol 135 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Ch.C. ZOUBOULIS ◽  
U. BLUME-PEYTAVI ◽  
Th. LENNERT ◽  
P.G. STAVROPOULOS ◽  
A. SCHWARZ ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Hyperparathyroidism ◽  
Cutaneous Necrosis ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Chryseobacterium spp-associated bacteraemia in a haemodialysis patient: a diagnostic challenge

2019 ◽  
Vol 12 (11) ◽  
pp. e232000
Author(s):  
Muhammad Junaid Ahsan ◽  
Soban Ahmad ◽  
Azka Latif ◽  
Joseph Thilumala Reddy
Keyword(s):  
End Stage Renal Disease ◽  
Rare Case ◽  
Haemodialysis Patient ◽  
Water Systems ◽  
Hospital Environment ◽  
Human Pathogen ◽  
Diagnostic Challenge ◽  
Negative Bacillus ◽  
Stage Renal Disease ◽  
End Stage

Chryseobacterium species are Gram-negative bacillus widely distributed in nature. It is a rare human pathogen that has been isolated from water systems and humid surfaces of the hospital environment. We report a rare case of Chryseobacterium bacteremia in an end-stage renal disease nursing home resident, that was diagnosed using multiplex PCR and was successfully treated with intravenous piperacillin–tazobactam combination.

Patients' Preferences Regarding Choice of End-Stage Renal Disease Treatment Options

2013 ◽  
Vol 37 (4) ◽  
pp. 359-369 ◽  
Author(s):  
Abdelmouttalib Maaroufi ◽  
Coraline Fafin ◽  
Sophie Mougel ◽  
Guillaume Favre ◽  
Barbara Seitz-Polski ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Disease Treatment ◽  
Stage Renal Disease ◽  
End Stage

Decisional conflict between treatment options among end-stage renal disease patients evaluated for kidney transplantation

2017 ◽  
Vol 31 (7) ◽  
pp. e12991 ◽  
Author(s):  
Laura McPherson ◽  
Mohua Basu ◽  
Jennifer Gander ◽  
Stephen O. Pastan ◽  
Sumit Mohan ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Treatment Options ◽  
Decisional Conflict ◽  
Stage Renal Disease ◽  
End Stage

Fulminant metastatic calcinosis with cutaneous necrosis in a child with end-stage renal disease and tertiary hyperparathyroidism

1996 ◽  
Vol 135 (4) ◽  
pp. 617-622 ◽  
Author(s):  
Ch.C. ZOUBOULIS ◽  
U. BLUME-PEYTAVI ◽  
Th. LENNERT ◽  
P.G. STAVROPOULOS ◽  
A. SCHWARZ ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Tertiary Hyperparathyroidism ◽  
Cutaneous Necrosis ◽  
Stage Renal Disease ◽  
End Stage

Parathyroid Carcinoma in a Chronic Hemodialysis Patient: Case Report and Review of the Literature

2005 ◽  
Vol 91 (6) ◽  
pp. 558-562 ◽  
Author(s):  
Maurizio Bossola ◽  
Luigi Tazza ◽  
Angela Ferrante ◽  
Stefania Giungi ◽  
Arnaldo Carbone ◽  
...  
Keyword(s):  
Renal Disease ◽  
End Stage Renal Disease ◽  
Parathyroid Carcinoma ◽  
Normal Population ◽  
Membranous Glomerulonephritis ◽  
Chronic Hemodialysis ◽  
Parathyroid Glands ◽  
Proliferating Cells ◽  
Stage Renal Disease ◽  
End Stage

Parathyroid carcinoma is a rare disease in normal population as well as in patients with end-stage renal disease. Approximately 700 cases have been reported and, of these, 20 occurred in patients receiving chronic hemodialysis. We describe a case of parathyroid carcinoma in a 59-year-old female patient with end-stage renal disease secondary to membranous glomerulonephritis treated by hemodialysis since 1995. In September 1998, the calcium level was 12.4 mg/dl and intact parathyroid hormone serum levels were 1366 pg/ml (normal range, 25-65). A routine ultrasonographic examination of the neck revealed enlargement of two parathyroid glands, the left inferior gland being the largest and measuring 2×3×2 cm. In October 1998, resection of two parathyroid glands was performed. On the basis of histology, which documented the presence of proliferating cells arranged in sheets or in a trabecular pattern, numerous mitosis and vascular invasion, a diagnosis of parathyroid carcinoma was made.

Sign in / Sign up

Export Citation Format

Share Document