Postoperative hypercapnic respiratory failure in patients with obstructive sleep apnoea: treatment with non-invasive ventilation

2008 ◽  
Vol 53 (2) ◽  
pp. 65-65
Author(s):  
Z Dorkova ◽  
A Somos ◽  
M Orolin ◽  
J Farah ◽  
P Joppa ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Invasive Ventilation ◽  
Hypercapnic Respiratory Failure ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Obstructive Sleep

scholarly journals Non-invasive ventilation in obesity hypoventilation syndrome without severe obstructive sleep apnoea

Thorax ◽  
2016 ◽  
Vol 71 (10) ◽  
pp. 899-906 ◽  
Author(s):  
Juan F Masa ◽  
Jaime Corral ◽  
Candela Caballero ◽  
Emilia Barrot ◽  
Joaquin Terán-Santos ◽  
...  
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Invasive Ventilation ◽  
Obesity Hypoventilation Syndrome ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Obstructive Sleep ◽  
Hypoventilation Syndrome ◽  
Obesity Hypoventilation

scholarly journals Severe Obstructive Sleep Apnoea Leading to Raised Intracranial Pressure Hydrocephalus in a Patient with Aqueduct Stenosis

2021 ◽  
Author(s):  
Hilary McLoughlin ◽  
Gearoid Coughlin ◽  
Iftikhar Nadeem ◽  
Emma Burke
Keyword(s):  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Raised Intracranial Pressure ◽  
Invasive Ventilation ◽  
Aqueduct Stenosis ◽  
Non Invasive ◽  
Non Invasive Ventilation ◽  
Obstructive Sleep ◽  
Potential Problems ◽  
Hypoventilation Syndrome

We present the case of a patient with severe obstructive sleep apnoea (OSA) and hypoventilation syndrome who had hydrocephalus and acquired aqueduct stenosis. A link between these conditions in our patient is postulated. We discuss the mechanisms through which this might have occurred and the potential problems which might arise in applying non-invasive ventilation to a patient with hydrocephalus.

scholarly journals Obesity hypoventilation syndrome

2019 ◽  
Vol 28 (151) ◽  
pp. 180097 ◽  
Author(s):  
Juan F. Masa ◽  
Jean-Louis Pépin ◽  
Jean-Christian Borel ◽  
Babak Mokhlesi ◽  
Patrick B. Murphy ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Obstructive Sleep Apnoea ◽  
Sleep Disordered Breathing ◽  
Sleep Apnoea ◽  
Obesity Hypoventilation Syndrome ◽  
Hypercapnic Respiratory Failure ◽  
Obstructive Sleep ◽  
Hypoventilation Syndrome ◽  
Obesity Hypoventilation ◽  
Disordered Breathing

Obesity hypoventilation syndrome (OHS) is defined as a combination of obesity (body mass index ≥30 kg·m−2), daytime hypercapnia (arterial carbon dioxide tension ≥45 mmHg) and sleep disordered breathing, after ruling out other disorders that may cause alveolar hypoventilation. OHS prevalence has been estimated to be ∼0.4% of the adult population. OHS is typically diagnosed during an episode of acute-on-chronic hypercapnic respiratory failure or when symptoms lead to pulmonary or sleep consultation in stable conditions. The diagnosis is firmly established after arterial blood gases and a sleep study. The presence of daytime hypercapnia is explained by several co-existing mechanisms such as obesity-related changes in the respiratory system, alterations in respiratory drive and breathing abnormalities during sleep. The most frequent comorbidities are metabolic and cardiovascular, mainly heart failure, coronary disease and pulmonary hypertension. Both continuous positive airway pressure (CPAP) and noninvasive ventilation (NIV) improve clinical symptoms, quality of life, gas exchange, and sleep disordered breathing. CPAP is considered the first-line treatment modality for OHS phenotype with concomitant severe obstructive sleep apnoea, whereas NIV is preferred in the minority of OHS patients with hypoventilation during sleep with no or milder forms of obstructive sleep apnoea (approximately <30% of OHS patients). Acute-on-chronic hypercapnic respiratory failure is habitually treated with NIV. Appropriate management of comorbidities including medications and rehabilitation programmes are key issues for improving prognosis.

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