scholarly journals Chordoid glioma in the thalamus of a child: Rare location and atypical imaging findings

2021 ◽  
pp. 20200108
Author(s):  
Cong Huang ◽  
Dengwei Gan ◽  
Botao Huang ◽  
Junde Luo ◽  
Xingshun Zhou ◽  
...  
Keyword(s):  
Parietal Lobe ◽  
Third Ventricle ◽  
Female Child ◽  
Low Grade ◽  
Intracranial Tumour ◽  
Imaging Findings ◽  
Suprasellar Region ◽  
Rare Location ◽  
Left Thalamus ◽  
Chordoid Glioma

Chordoid glioma is a rare intracranial tumour, which usually occurs in middle-aged female patients, mainly in the third ventricle, hypothalamus and suprasellar region. It can reportedly occur in the temporal–parietal lobe, occipital horn of the lateral ventricle and left thalamus. Here, we report a case of chordoid glioma in the thalamic region of a female child, which is different from the previously reported chordoid glioma in the left thalamus. Given its atypical location and imaging findings, it is often misdiagnosed as low-grade glioma before operation. Through the study of this case, we recognized the atypical imaging manifestations of chordoid glioma in a rare location.

scholarly journals Chordoid Glioma as a Differential Diagnosis of Anterior Third Ventricle Tumours: A Rare Case Report and Five-Year Follow-Up

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Kristin Suetens ◽  
Jeroen Swinnen ◽  
Linde Stessens ◽  
Sofie Van Cauter ◽  
Geert Gelin
Keyword(s):  
Anterior Part ◽  
Third Ventricle ◽  
Tumour Resection ◽  
Low Grade ◽  
Residual Tumour ◽  
Rare Case Report ◽  
Tumour Entity ◽  
Chordoid Glioma ◽  
Third Ventricle Tumours

Chordoid glioma is a rare and relatively recently defined tumour entity. Worldwide there have only been around 90 cases described until now. A chordoid glioma comprises a low-grade suprasellar neuroepithelial neoplasm originating in the anterior part of the third ventricle, with consistent radiological features on MRI. This lesion should be considered as a differential of third ventricle tumours. The patient described in this paper is quite unique in the sense that despite only partial tumour resection was obtained, the residual tumour was not progressive during several years of follow-up. Preoperative recognition of this disease entity is crucial to modify the treatment approach and improve patient outcome.

scholarly journals Chordoid Glioma of the Third Ventricular with Three less Common Patterns and Three Rare Patterns

2020 ◽  
Author(s):  
xiaomei ma ◽  
zhi zhu ◽  
yin wang ◽  
weiqing li
Keyword(s):  
Tumor Cells ◽  
Third Ventricle ◽  
Collagen Matrix ◽  
Low Grade ◽  
Blurred Vision ◽  
The Third ◽  
Irregular Shapes ◽  
Chordoid Glioma ◽  
Glioma Case

Abstract BackgroundChordoid gliomas are rare, low-grade neoplasms of the third ventricle. In the updated 4th edition of the 2016 WHO classification of tumours of the CNS, it described some three less common histological patterns and rare tissue patterns. Case presentationHere we reported a case with all the uncommon patterns. It was a 52-year-old woman with dizziness and blurred vision. Imaging showed a solid tumor located in the third ventricle with a well-circumscribed border. Histological, almost tumor cells formed into atypical glands with different sizes and irregular shapes in an abundant of solid or loosely collagen matrix. Some tumor cells formed into papillary patterns, micro-papillary patterns. pseudoglandular patterns. Some focal tumor cells were spindle-shape. Only few epithelioid tumor cells formed into clusters and cords embedded into a myxoid stroma like the chordoma. No anaplastic features were identified in any lesion. Immunohistochemically, all the tumor cells were strong reactivity for TTF-1. Some tumor cells strong but focal reactivity for GFAP, NEU-N, and CD34. It showed a recurrent D463H missense mutation in PRKCA. All these findings confirm that the diagnosis was chordoid glioma of the third ventricular. ConclusionsThere may be lots of histopathological features in one chordoid glioma case. It maybe suggested that PRKCA D463H mutation and TTF-1 positive may help to diagnose it.

scholarly journals Chordoid Glioma of the Third Ventricular with Rare Patterns and Mutation in PRKCA: a case report and review of literature

2020 ◽  
Author(s):  
xiaomei ma ◽  
zhi zhu ◽  
yin wang ◽  
weiqing li
Keyword(s):  
Tumor Cells ◽  
Third Ventricle ◽  
Collagen Matrix ◽  
Low Grade ◽  
Blurred Vision ◽  
Case Presentation ◽  
The Third ◽  
Irregular Shapes ◽  
Chordoid Glioma

Abstract Background: Chordoid gliomas are rare, low-grade neoplasms of the third ventricle. In the updated 4th edition of the 2016 WHO classification of tumours of the CNS, it described some three less common histological patterns and rare tissue patterns. Case presentation:Here we reported a case with all the uncommon patterns. It was a 52-year-old woman with dizziness and blurred vision. Imaging showed a solid tumor located in the third ventricle with a well-circumscribed border. Histological, almost tumor cells formed into atypical glands with different sizes and irregular shapes in an abundant of solid or loosely collagen matrix. Some tumor cells formed into papillary patterns, micro-papillary patterns. pseudoglandular patterns. Some focal tumor cells were spindle-shape. Only few epithelioid tumor cells formed into clusters and cords embedded into a myxoid stroma like the chordoma. No anaplastic features were identified in any lesion. Immunohistochemically, all the tumor cells were strong reactivity for TTF-1. Some tumor cells strong but focal reactivity for GFAP, NEU-N, and CD34. It showed a recurrent D463H missense mutation in PRKCA. All these findings confirm that the diagnosis was chordoid glioma of the third ventricular. Conclusions: There may be lots of histopathological features in one chordoid glioma case. It maybe suggested that PRKCA D463H mutation and TTF-1 positive may help to diagnose it.

scholarly journals Chordoid Glioma of the Third Ventricular with Rare Patterns and Mutation in PRKCA: a case report and review of literature

2020 ◽  
Author(s):  
xiaomei ma ◽  
zhi zhu ◽  
yin wang ◽  
weiqing li
Keyword(s):  
Tumor Cells ◽  
Third Ventricle ◽  
Collagen Matrix ◽  
Low Grade ◽  
Blurred Vision ◽  
Case Presentation ◽  
The Third ◽  
Irregular Shapes ◽  
Chordoid Glioma

Abstract Background: Chordoid gliomas are rare, low-grade neoplasms of the third ventricle. In the updated 4th edition of the 2016 WHO classification of tumours of the CNS, it described some three less common histological patterns and rare tissue patterns. Case presentation:Here we reported a case with all the uncommon patterns. It was a 52-year-old woman with dizziness and blurred vision. Imaging showed a solid tumor located in the third ventricle with a well-circumscribed border. Histological, almost tumor cells formed into atypical glands with different sizes and irregular shapes in an abundant of solid or loosely collagen matrix. Some tumor cells formed into papillary patterns, micro-papillary patterns. pseudoglandular patterns. Some focal tumor cells were spindle-shape. Only few epithelioid tumor cells formed into clusters and cords embedded into a myxoid stroma like the chordoma. No anaplastic features were identified in any lesion. Immunohistochemically, all the tumor cells were strong reactivity for TTF-1. Some tumor cells strong but focal reactivity for GFAP, NEU-N, and CD34. It showed a recurrent D463H missense mutation in PRKCA. All these findings confirm that the diagnosis was chordoid glioma of the third ventricular. Conclusions: There may be lots of histopathological features in one chordoid glioma case. It maybe suggested that PRKCA D463H mutation and TTF-1 positive may help to diagnose it.

scholarly journals CT, MRI, and FDG-PET imaging findings of low-grade extrauterine endometrial stromal sarcoma arising from the mesentery: A case report

2021 ◽  
Vol 16 (9) ◽  
pp. 2774-2779
Author(s):  
Satoshi Suzuki ◽  
Ryo Kurokawa ◽  
Tetsushi Tsuruga ◽  
Mayuyo Mori‑Uchino ◽  
Haruka Nishida ◽  
...  
Keyword(s):  
Case Report ◽  
Pet Imaging ◽  
Fdg Pet ◽  
Endometrial Stromal Sarcoma ◽  
Low Grade ◽  
Imaging Findings ◽  
Stromal Sarcoma

scholarly journals LGG-06. LONG-TERM OUTCOME OF NEWLY DIAGNOSED LOW GRADE GLIOMA

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii367-iii367
Author(s):  
Nongnuch Sirachainan ◽  
Attaporn Boongerd ◽  
Samart Pakakasama ◽  
Usanarat Anurathapan ◽  
Ake Hansasuta ◽  
...  
Keyword(s):  
Surgical Management ◽  
Progression Free Survival ◽  
Low Grade Glioma ◽  
Low Grade ◽  
Newly Diagnosed ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Common Location ◽  
Suprasellar Region

Abstract INTRODUCTION Low grade glioma (LGG) is the most common central nervous system (CNS) tumor in children accounted for 30–50%. Regarding benign characteristic of disease, surgical management remains the mainstay of treatment. However, surgical approach is limited in some conditions such as location at brainstem or infiltrative tumor. Chemotherapy and radiation treatments have been included in order to control tumor progression. The 5-years survival rate is approach 90% especially in patients who receive complete resection. However, the outcome of children with LGG in low to middle income is limited. Therefore, the aim of the study was to determine long-term outcome of children with newly diagnosed LGG. METHODS A retrospective study enrolled children aged <18 years who were newly diagnosed LGG during January 2006- December 2019. Diagnosis of LGG was confirmed by histological findings of grade I and II according to WHO criteria. RESULTS A total of 40 patients, female to male ratio was 1:1.35 and mean (SD) for age was 6.7 (4.0) years. The most common location was optic chiasmatic pathway (42.5%), followed by suprasellar region (25.0%). Sixty percent of patients received at least partial tumor removal. Chemotherapy and radiation had been used in 70% and 10.0% respectively. The 10-year progression free survival was 74.1±11.4% and overall survival was 96.2±3.8%. SUMMARY: Treatment of Pediatric LGG mainly required surgical management, however, chemotherapy and radiation had been used in progressive disease. The outcome was excellent.

scholarly journals Atypical Chordoid Glioma of the Third Ventricle: A Case Report

2015 ◽  
Vol 04 (02) ◽  
pp. 124-127
Author(s):  
R. Mittal ◽  
Amitesh Dubey ◽  
S. Singhvi ◽  
Manash Bora
Keyword(s):  
Case Report ◽  
Third Ventricle ◽  
The Third ◽  
Chordoid Glioma

Imaging findings of thoracic low-grade fibromyxoid sarcoma: report of three cases

2009 ◽  
Vol 27 (9) ◽  
pp. 375-380 ◽  
Author(s):  
Eriko Maeda ◽  
Satoshi Ohta ◽  
Takeyuki Watadani ◽  
Akiteru Goto ◽  
Atsushi Nakajima ◽  
...  
Keyword(s):  
Low Grade ◽  
Imaging Findings ◽  
Fibromyxoid Sarcoma
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