Shear wave elastography in differentiating between benign and malignant cervical lymph nodes in patients with oral carcinoma

Objectives: To evaluate shear wave elastography in differentiating between benign and malignant cervical lymph nodes in patients with oral carcinoma. Methods: 77 patients with oral squamous cell carcinoma were examined by B-mode and shear wave elastography with a 14 MHz linear transducer. The integrated shear wave elastography software allowed the operator to place regions of interest of various sizes within the elastography window, and automatically displayed shear elastic modulus data (kPa) for each region of interest. The relationship between size and shear elastic modulus of cervical lymph nodes was assessed by Pearson's rank correlation test. The shear elastic modulus of cervical lymph nodes in benign and malignant were evaluated using the Mann–Whitney U test. The analyses were used with a 5% significance level. Results: We plotted shear elastic modulus (X) against minimal axial diameter of cervical lymph nodes (Y), and observed a significant correlation [ Y = 0.091 X + 4.648 (R2 = 0.603, p = 0.000, N = 77)]. Furthermore, the shear elastic modulus of the malignant cervical lymph nodes (105.9 ± 5.2 kPa) was higher than that of benign (11.9 ± 4.4 kPa, p = 0.000). Conclusions: The shear wave elastography is an effective technique for the objectively and quantitatively diagnosis of cervical lymph node metastases of the oral carcinoma.

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Post-Operative Assessment of Ulnar Nerve Tension Using Shear-Wave Elastography

Neurology International ◽

10.3390/neurolint13030046 ◽

2021 ◽

Vol 13 (3) ◽

pp. 469-476

Author(s):

Sebastien Durand ◽

Wassim Raffoul ◽

Thierry Christen ◽

Nadine Pedrazzi

Keyword(s):

Elastic Modulus ◽

Shear Wave ◽

Ulnar Nerve ◽

Shear Wave Elastography ◽

Elbow Flexion ◽

Ulnar Nerve Compression ◽

Nerve Decompression ◽

Shear Elastic Modulus ◽

Anterior Transposition ◽

Operative Assessment

Background: Ulnar nerve compression at the elbow level is the second-most common entrapment neuropathy. The aim of this study was to use shear-wave elastography for the quantification of ulnar nerve elasticity in patients after ulnar nerve decompression with anterior transposition and in the contralateral non-operative side. Method: Eleven patients with confirmed diagnosis and ulnar nerve decompression with anterior transposition were included and examinations were performed on an AixplorerTM ultrasound system (Supersonic Imagine, Aix-en-Provence, France). Results: We observed significant differences at 0-degree (p < 0.001), 45-degree (p < 0.05), 90-degree (p < 0.01) and 120-degree (p < 0.001) elbow flexion in the shear elastic modulus of the ulnar nerve in the operative and non-operative sides. There were no statistically significant differences between the elasticity values of the ulnar nerve after transposition at 0-degree elbow flexion and in the non-operative side at 120-degree elbow flexion (p = 0.39), or in the ulnar nerve after transposition at 120-degree elbow flexion and in the non-operative side at 0-degree elbow flexion (p = 0.09). Conclusion: Shear-wave elastography has the potential to be used postoperatively as a method for assessing nerve tension noninvasively by the estimation of mechanical properties, such as the shear elastic modulus.

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Effect of Rest Duration Between Static Stretching on Passive Stiffness of Medial Gastrocnemius Muscle In Vivo

Journal of Sport Rehabilitation ◽

10.1123/jsr.2018-0376 ◽

2020 ◽

Vol 29 (5) ◽

pp. 578-582

Author(s):

Masatoshi Nakamura ◽

Shigeru Sato ◽

Ryosuke Kiyono ◽

Nobushige Takahashi ◽

Tomoichi Yoshida

Keyword(s):

Elastic Modulus ◽

Shear Wave ◽

Repeated Measures ◽

Shear Wave Elastography ◽

Muscle Stiffness ◽

Medial Gastrocnemius ◽

Static Stretching ◽

Shear Elastic Modulus ◽

Before And After

Context: In clinical and sports settings, static stretching (SS) is usually performed to increase range of motion (ROM) and decrease passive muscle stiffness. Recently, the shear elastic modulus was measured by ultrasonic shear wave elastography as an index of muscle stiffness. Previous studies reported that the shear elastic modulus measured by ultrasound shear wave elastography decreased after SS, and the effects of SS on shear elastic modulus were likely affected by rest duration between sets of SS. Objective: To investigate the acute effects of SS with different rest durations on ROM and shear elastic modulus of gastrocnemius and to clarify whether the rest duration between sets of SS decreases the shear elastic modulus. Design: A randomized, repeated-measures experimental design. Setting: University laboratory. Participants: Sixteen healthy males volunteered to participate in the study (age 21.3 [0.8] y; height 171.8 [5.1] cm; weight 63.1 [4.5] kg). Main Outcome Measures: Each participant underwent 3 different rest interval durations during SS (ie, long rest duration: 90 s; normal rest duration: 30 s; and short rest duration: 10 s). This SS technique was repeated 10 times, thus lasting a total of 300 seconds with different rest durations in each protocol. The dorsiflexion ROM and shear elastic modulus were measured before and after SS. Results: Our results revealed that dorsiflexion ROM and shear elastic modulus were changed after 300-second SS; however, no effects of the rest duration between sets of SS were observed. Conclusions: In terms of decreasing the shear elastic modulus, clinicians and coaches should not focus on the rest duration when SS intervention is performed.

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Change in Shear Elastic Modulus of Thigh Muscle by Changing Muscle Length Using Ultrasound Shear Wave Elastography in Beagle Dogs

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.1055/s-0039-1692449 ◽

2019 ◽

Vol 32 (06) ◽

pp. 454-459 ◽

Cited By ~ 2

Author(s):

Miki Shimizu ◽

Yu Ito

Keyword(s):

Elastic Modulus ◽

Shear Wave ◽

Vastus Lateralis ◽

Muscle Length ◽

Shear Wave Elastography ◽

Biceps Femoris ◽

Percentage Change ◽

Thigh Muscle ◽

Beagle Dogs ◽

Shear Elastic Modulus

Objectives This study investigated the relationship between the change in the shear elastic modulus and the change in muscle length using ultrasound shear wave elastography. Study Design Four thigh muscles, cranial part of the sartorius, vastus lateralis, biceps femoris and semitendinosus muscles, of 21 pelvic limbs in 12 clinically healthy Beagle dogs were used. The muscle length was estimated using a radiograph and the flexed and extended positions of the coxofemoral and stifle joints, respectively. The shear elastic modulus (kPa) was measured in two joint positions using ultrasound shear wave elastography. Shear elastic modulus was expressed as median of 10 consecutive measurements. The percentage change of elastic modulus was calculated from the shear elastic modulus in elongated condition and pre-elongated condition of muscle. Results The elastic modulus of all muscles increased when the muscle was elongated. The shear elastic modulus for both joint positions and the percentage change of the shear elastic modulus (%) in cranial part of the sartorius were highest in all muscles. Intra-observer correlation coefficient (1.2) was 0.75 to 0.96 and intra-observer correlation coefficients (2.2) was 0.46 to 0.96. Conclusion This study revealed that the shear elastic modulus of muscle was changed by the change in muscle length and increased when the muscle was elongated. Ultrasound shear wave elastography can be used to assess the elastic properties of canine muscle.

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The value of quantitative shear wave elastography in differentiating the cervical lymph nodes in patients with thyroid nodules

Journal of Medical Ultrasonics ◽

10.1007/s10396-017-0819-0 ◽

2017 ◽

Vol 45 (2) ◽

pp. 251-259 ◽

Cited By ~ 7

Author(s):

Jun You ◽

Juan Chen ◽

Feixiang Xiang ◽

Yue Song ◽

Simai Khamis ◽

...

Keyword(s):

Lymph Nodes ◽

Shear Wave ◽

Thyroid Nodules ◽

Shear Wave Elastography ◽

Cervical Lymph Nodes

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Muscle shear elastic modulus of paraspinals measured using shear wave elastography correlates with muscle activity, but depends on image quality

Journal of Science and Medicine in Sport ◽

10.1016/j.jsams.2019.08.285 ◽

2019 ◽

Vol 22 ◽

pp. S72

Author(s):

L. Tier ◽

P. Hodges ◽

S. Salomoni

Keyword(s):

Elastic Modulus ◽

Image Quality ◽

Shear Wave ◽

Muscle Activity ◽

Shear Wave Elastography ◽

Shear Elastic Modulus

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The diagnostic performance of shear wave elastography for malignant cervical lymph nodes: A systematic review and meta-analysis

European Radiology ◽

10.1007/s00330-016-4378-3 ◽

2016 ◽

Vol 27 (1) ◽

pp. 222-230 ◽

Cited By ~ 20

Author(s):

Chong Hyun Suh ◽

Young Jun Choi ◽

Jung Hwan Baek ◽

Jeong Hyun Lee

Keyword(s):

Systematic Review ◽

Lymph Nodes ◽

Shear Wave ◽

Diagnostic Performance ◽

Meta Analysis ◽

Shear Wave Elastography ◽

Cervical Lymph Nodes

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The Role of Ultrasound and Shear-Wave Elastography in Evaluation of Cervical Lymph Nodes

BioMed Research International ◽

10.1155/2019/4318251 ◽

2019 ◽

Vol 2019 ◽

pp. 1-6 ◽

Cited By ~ 6

Author(s):

Jan Heřman ◽

Zuzana Sedláčková ◽

Tomáš Fürst ◽

Jaromír Vachutka ◽

Richard Salzman ◽

...

Keyword(s):

Lymph Nodes ◽

Shear Wave ◽

Sensitivity And Specificity ◽

Predictive Power ◽

Shear Wave Elastography ◽

Final Diagnosis ◽

Neck Mass ◽

Cervical Lymph Nodes ◽

Axis Ratio ◽

Ultrasound Parameters

Aim. To evaluate the prognostic value of ultrasound and shear-wave elastography (SWE) in diagnosing malignant cervical lymph nodes. Methods. A total of 99 patients with enlarged lymph nodes (99 lymph nodes presenting as a neck mass) were examined clinically with conventional ultrasound including Doppler examination and shear-wave elastography. The results of the examinations were compared with the final diagnosis. Results. There were 43 benign and 56 malignant lymph nodes in our cohort. Age and sex were significant predictors of malignancy. The standard ultrasound parameters—node size, long/short axis ratio, hilum, vascularization, and the presence of microcalcifications—were also statistically significant. Lymph node volume combined with age showed the best predictive power. The maximum stiffness found on SWE was also a significant predictor of malignancy. The combination of epidemiologic, classic ultrasound, and elastographic parameters yielded the highest sensitivity and specificity in the prediction of malignancy; however, the additional impact of elastographic parameters was low. Conclusion. A combination of epidemiologic and classic ultrasound parameters can discriminate between malignant and benign lymph nodes with satisfactory sensitivity and specificity. Examining the stiffness of lymph nodes by means of SWE does not add much new predictive power.

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