scholarly journals Embryonic Development and Implantation Related Gene Expression of Oocyte Reconstructed with Bovine Trophoblast Cells

2012 ◽  
Vol 58 (4) ◽  
pp. 425-431 ◽  
Author(s):  
Islam M. SAADELDIN ◽  
WooJae CHOI ◽  
Bego ROIBAS DA TORRE ◽  
BongHan KIM ◽  
ByeongChun LEE ◽  
...  
Keyword(s):  
Gene Expression ◽  
Embryonic Development ◽  
Related Gene ◽  
Trophoblast Cells

scholarly journals Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development

1999 ◽  
Vol 40 (11) ◽  
pp. 1967-1977 ◽  
Author(s):  
Yuko Terasawa ◽  
Sylvaine J. Cases ◽  
Jinny S. Wong ◽  
Haris Jamil ◽  
Sumana Jothi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Embryonic Development ◽  
Apolipoprotein B ◽  
Yolk Sac ◽  
Related Gene ◽  
Lipoprotein Secretion ◽  
Ultrastructural Characteristics

m6a Methylation Inhibition by Cycloleucine Impaired Porcine Oocyte Meiosis and Early Embryonic Development via Remodeling Histone Modifications and Altering Metabolism Related Gene Expression in Blastocysts

2020 ◽  
Author(s):  
Meng Zhang ◽  
Sheng Zhang ◽  
Yanhui Zhai ◽  
Yu Han ◽  
Rong Huang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Embryonic Development ◽  
Histone Modifications ◽  
Early Embryo ◽  
Early Embryonic Development ◽  
Related Gene ◽  
Cell Stage ◽  
Oocyte Meiosis ◽  
Porcine Oocyte ◽  
Parthenogenetic Embryos

Abstract BackgroundOocytes maturation and early embryo development were regulated precisely by a series of factors at transcriptional and posttranslational levels. N6-methyladenosine (m6A) is the most prevalent modification in mRNA as a crucial regulator in RNA metabolism and gene regulation. However, the role of m6A on porcine oocyte maturation and early embryogenesis is largely unknown. ResultsHere, we found that oocytes treated with cycloleucine (CL), an inhibitor of m6A, could impair cumulus expansion, elevate mitochondrial reactive oxygen species (ROS) concentration and decreased oocytes maturation which partially caused by disturbed spindle organization and chromosomes alignment. Moreover, our results indicated that the CL treated parthenogenetic embryos arrested at 4-cell stage and showed worse blastocyst quality. CL treatment not only decreased the methylation levels of nucleic acid, H3K4me3 and H3K9me3, while increased the acetylation level of H4K16 during parthenogenetic embryos development in pigs. Furthermore, single cell RNA-seq (scRNA-seq) analysis indicated that CL treatment dramatically elevated the expression of metabolism-related (SLC16A1 and MAIG3 etc.) and maternal related (BTG4, WEE2 and BMP15 etc.) genes at blastocyst stage. ConclusionsTaken together, we found that m6A methylation inhibition by CL impaired porcine oocyte meiosis and early embryonic development via remodeling histone modifications and altering metabolism related gene expression in blastocysts.

Regulation of embryonic development and apoptotic-related gene expression by brain-derived neurotrophic factor in two different culture conditions in ovine

2015 ◽  
Vol 84 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Amir Hossein Abazari-Kia ◽  
Maryam Dehghani-Mohammadabadi ◽  
Abdollah Mohammadi-Sangcheshmeh ◽  
Mahdi Zhandi ◽  
Mohammad Salehi
Keyword(s):  
Gene Expression ◽  
Embryonic Development ◽  
Neurotrophic Factor ◽  
Brain Derived Neurotrophic Factor ◽  
Culture Conditions ◽  
Related Gene

Effect of maternal rearing on lipid metabolism-related gene expression in offspring broilers during embryonic development

2010 ◽  
Vol 51 (4) ◽  
pp. 500-506 ◽  
Author(s):  
S. Zhao ◽  
H. Ma ◽  
J. Miao ◽  
S. Zou ◽  
W. Chen
Keyword(s):  
Gene Expression ◽  
Lipid Metabolism ◽  
Embryonic Development ◽  
Related Gene

Endogenous hydrogen sulfide promotes human preimplantation embryonic development by regulating metabolism-related gene expression

Nitric Oxide ◽  
2022 ◽  
Author(s):  
Qing Sun ◽  
Huixian Zhong ◽  
Yongjian Yue ◽  
Feng Xiong ◽  
Lipeng Chen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Hydrogen Sulfide ◽  
Embryonic Development ◽  
Related Gene
Sign in / Sign up

Export Citation Format

Share Document