Profiling Proteinic Changes Induced by Vildagliptin Treatment in a Mouse Lung Transplantation Model: The Role of Kininogen-1

2017 ◽  
Vol 22 ◽  
pp. 128-137 ◽  
Author(s):  
Zheng Tang ◽  
Wei Zhai ◽  
Zhiwei Wang ◽  
Zhipeng Hu ◽  
Min Zhang
Keyword(s):  
Lung Transplantation ◽  
Mouse Lung ◽  
Transplantation Model

scholarly journals Magnetisation transfer as a biomarker for chronic airway fibrosis in a mouse lung transplantation model

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
David Kenkel ◽  
Yoshito Yamada ◽  
Markus Weiger ◽  
Moritz C. Wurnig ◽  
Wolfgang Jungraithmayr ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Mouse Lung ◽  
Magnetisation Transfer ◽  
Airway Fibrosis ◽  
Transplantation Model ◽  
Chronic Airway

Treatment With Omental Cells Reduces Acute Inflammation In An Allogenic Mouse Lung Transplantation Model

2012 ◽  
Author(s):  
Nick Huang ◽  
Melissa Medina ◽  
Periannan Sethupathi ◽  
Alicia A. Martin ◽  
Wolfgang Jungraithmayr ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Acute Inflammation ◽  
Mouse Lung ◽  
Transplantation Model

Role of recombinant hirudin in a pig-to-human lung transplantation model

2002 ◽  
Vol 34 (6) ◽  
pp. 2384-2386 ◽  
Author(s):  
H Schelzig ◽  
A Vogel ◽  
C Krischer ◽  
F Simon ◽  
D Abendroth
Keyword(s):  
Lung Transplantation ◽  
Human Lung ◽  
Recombinant Hirudin ◽  
Transplantation Model

Navigating the Road to Transplant in Pulmonary Arterial Hypertension: A Road Less Taken

2016 ◽  
Vol 15 (1) ◽  
pp. 12-13
Author(s):  
Adaani E. Frost ◽  
Harrison W. Farber
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Lung Transplantation ◽  
Small Cell ◽  
Small Cell Lung ◽  
Donor Organ ◽  
The Road ◽  
Lung Allocation Score ◽  
Pulmonary Arterial

Dramatic advances in therapy for pulmonary arterial hypertension (PAH) in the last 20 years have improved survival from a median of 2.5 years in the pretreatment era to 7.5 years currently. However, impressive as that may seem, it is important to note that a median survival of 7.5 years is equivalent to that of surgically resected non-small cell lung cancer, thus underscoring the importance of lung transplantation as a treatment option in patients with PAH. In this edition of Advances, Edelman has reviewed the pathway to transplantation for patients with PAH, detailing the recommendations for timing of referral, listing for lung transplantation, the role of the lung allocation score in allocating a donor organ, and the outcome of lung transplantation.

scholarly journals RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 70
Author(s):  
Malgorzata Kloc ◽  
Ahmed Uosef ◽  
Martha Villagran ◽  
Robert Zdanowski ◽  
Jacek Z. Kubiak ◽  
...  
Keyword(s):  
Immune Response ◽  
Circadian Rhythm ◽  
Immune Cells ◽  
Chronic Rejection ◽  
Cardiac Transplantation ◽  
Small Gtpase ◽  
Eukaryotic Cells ◽  
Transplantation Model

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As such, they also regulate the phenotypes and functions of macrophages in the immune response and beyond. Here, we review the results of our and other’s studies on the role of the actin and RhoA pathway in shaping the macrophage functions in general and macrophage immune response during the development of chronic (long term) rejection of allografts in the rodent cardiac transplantation model. We focus on the importance of timing of the macrophage functions in chronic rejection and how the circadian rhythm may affect the anti-chronic rejection therapies.

scholarly journals Experience-Dependent Pathological Variations in Minor-Mismatched Mouse Lung Transplantation

2021 ◽  
Vol 40 (4) ◽  
pp. S348
Author(s):  
M. Kawashima ◽  
J. Oliver ◽  
T. Watanabe ◽  
N. Huang ◽  
C. Konoeda ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Mouse Lung
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