Important role of haematopoietic chimerism following Immunosuppressive drug withdrawal in a porcine lung transplantation model

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
G Warnecke ◽  
B Kruse ◽  
S Thissen ◽  
M Avsar ◽  
B Pabst ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Drug Withdrawal ◽  
Immunosuppressive Drug ◽  
Transplantation Model

scholarly journals Role of siroliumus, a novel immunosuppressive drug in heart and lung transplantation

2004 ◽  
Vol 98 (9) ◽  
pp. 892-897 ◽  
Author(s):  
David Shitrit ◽  
Alex Yussim ◽  
Mordechai R Kramer
Keyword(s):  
Lung Transplantation ◽  
Immunosuppressive Drug

Role of recombinant hirudin in a pig-to-human lung transplantation model

2002 ◽  
Vol 34 (6) ◽  
pp. 2384-2386 ◽  
Author(s):  
H Schelzig ◽  
A Vogel ◽  
C Krischer ◽  
F Simon ◽  
D Abendroth
Keyword(s):  
Lung Transplantation ◽  
Human Lung ◽  
Recombinant Hirudin ◽  
Transplantation Model

Profiling Proteinic Changes Induced by Vildagliptin Treatment in a Mouse Lung Transplantation Model: The Role of Kininogen-1

2017 ◽  
Vol 22 ◽  
pp. 128-137 ◽  
Author(s):  
Zheng Tang ◽  
Wei Zhai ◽  
Zhiwei Wang ◽  
Zhipeng Hu ◽  
Min Zhang
Keyword(s):  
Lung Transplantation ◽  
Mouse Lung ◽  
Transplantation Model

Navigating the Road to Transplant in Pulmonary Arterial Hypertension: A Road Less Taken

2016 ◽  
Vol 15 (1) ◽  
pp. 12-13
Author(s):  
Adaani E. Frost ◽  
Harrison W. Farber
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Lung Transplantation ◽  
Small Cell ◽  
Small Cell Lung ◽  
Donor Organ ◽  
The Road ◽  
Lung Allocation Score ◽  
Pulmonary Arterial

Dramatic advances in therapy for pulmonary arterial hypertension (PAH) in the last 20 years have improved survival from a median of 2.5 years in the pretreatment era to 7.5 years currently. However, impressive as that may seem, it is important to note that a median survival of 7.5 years is equivalent to that of surgically resected non-small cell lung cancer, thus underscoring the importance of lung transplantation as a treatment option in patients with PAH. In this edition of Advances, Edelman has reviewed the pathway to transplantation for patients with PAH, detailing the recommendations for timing of referral, listing for lung transplantation, the role of the lung allocation score in allocating a donor organ, and the outcome of lung transplantation.

scholarly journals RhoA- and Actin-Dependent Functions of Macrophages from the Rodent Cardiac Transplantation Model Perspective -Timing Is the Essence

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 70
Author(s):  
Malgorzata Kloc ◽  
Ahmed Uosef ◽  
Martha Villagran ◽  
Robert Zdanowski ◽  
Jacek Z. Kubiak ◽  
...  
Keyword(s):  
Immune Response ◽  
Circadian Rhythm ◽  
Immune Cells ◽  
Chronic Rejection ◽  
Cardiac Transplantation ◽  
Small Gtpase ◽  
Eukaryotic Cells ◽  
Transplantation Model

The small GTPase RhoA, and its down-stream effector ROCK kinase, and the interacting Rac1 and mTORC2 pathways, are the principal regulators of the actin cytoskeleton and actin-related functions in all eukaryotic cells, including the immune cells. As such, they also regulate the phenotypes and functions of macrophages in the immune response and beyond. Here, we review the results of our and other’s studies on the role of the actin and RhoA pathway in shaping the macrophage functions in general and macrophage immune response during the development of chronic (long term) rejection of allografts in the rodent cardiac transplantation model. We focus on the importance of timing of the macrophage functions in chronic rejection and how the circadian rhythm may affect the anti-chronic rejection therapies.

Development of a more practical Ex Vivo rabbit lung transplantation model

1998 ◽  
Vol 30 (7) ◽  
pp. 3372-3373
Author(s):  
M Suga ◽  
I Koyama ◽  
M Onizuka ◽  
R Morita ◽  
N Ogawa ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Ex Vivo ◽  
Rabbit Lung ◽  
Transplantation Model
Sign in / Sign up

Export Citation Format

Share Document