Synthesis, Absolute Configuration and Biological Activities of Both Enantiomers of 2-(5,7-Dichloro-3-indolyl)propionic Acid: a Novel Dichloroindole Auxin and Antiauxin

2004 ◽  
Vol 68 (6) ◽  
pp. 1287-1292 ◽  
Author(s):  
Masato KATAYAMA ◽  
Yasuhito KATO ◽  
Shingo MARUMO
Keyword(s):  
Propionic Acid ◽  
Absolute Configuration ◽  
Biological Activities

scholarly journals Chemistry of bleomycin. XV. Absolute configuration of .BETA.-amino-.BETA.-(4-amino-6-carboxy-5-methylpyrimidin-2-yl)-propionic acid, an amine component of bleomycin.

1976 ◽  
Vol 29 (7) ◽  
pp. 762-764 ◽  
Author(s):  
HIKARU NAKAMURA ◽  
TAKEO YOSHIOKA ◽  
TOMOHISA TAKITA ◽  
HAMAO UMEZAWA ◽  
YASUHIKO MURAOKA ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Absolute Configuration

scholarly journals Duclauxin Derivatives From Fungi and Their Biological Activities

2021 ◽  
Vol 12 ◽  
Author(s):  
Hamza Shahid ◽  
Teng Cai ◽  
Yuyang Wang ◽  
Caiqing Zheng ◽  
Yuting Yang ◽  
...  
Keyword(s):  
Phylogenetic Analysis ◽  
Tumor Cell ◽  
Absolute Configuration ◽  
Mitochondrial Respiration ◽  
Biological Activities ◽  
Atp Synthesis ◽  
Medical Applications ◽  
Tumor Cell Lines ◽  
Chemical Structures ◽  
Cyclopentane Ring

Duclauxin is a heptacyclic oligophenalenone dimer consisting of an isocoumarin and a dihydroisocoumarin unit. These two tricyclic moieties are joined by a cyclopentane ring to form a unique hinge or castanets-like structure. Duclauxin is effective against numerous tumor cell lines because it prevents adenosine triphosphate (ATP) synthesis by inhibiting mitochondrial respiration. There are about 36 reported natural duclauxin analogs mainly produced by 9 Penicillium and Talaromyces species (T. duclauxii, T. aculeatus, T. stipitatus, T. bacillisporus, T. verruculosus, T. macrosporus, P. herquei, P. manginii, and Talaromyces sp.). These metabolites exhibit remarkable biological activities, including antitumor, enzyme inhibition, and antimicrobial, showing tremendous potential in agricultural and medical applications. This review highlights the chemical structures and biological activities of fungal duclauxins, together with biosynthesis, absolute configuration, and mode of action for important duclauxins. Furthermore, phylogenetic analysis and correct names of Penicillium and Talaromyces species producing duclauxins are presented in this review.

Absolute configuration of 2-hydroxy-2-(1-naphthyl)propionic acid as determined by the 1H NMR anisotropy method

1999 ◽  
Vol 10 (21) ◽  
pp. 4075-4078 ◽  
Author(s):  
Akio Ichikawa ◽  
Shuntaro Hiradate ◽  
Akinori Sugio ◽  
Shunsuke Kuwahara ◽  
Masataka Watanabe ◽  
...  
Keyword(s):  
Propionic Acid ◽  
1H Nmr ◽  
Absolute Configuration

Absolute configuration of 2-methoxy-2-(2-naphthyl)propionic acid as determined by the 1 H NMR anisotropy method

2000 ◽  
Vol 11 (13) ◽  
pp. 2669-2675 ◽  
Author(s):  
Akio Ichikawa ◽  
Syuntaro Hiradate ◽  
Akinori Sugio ◽  
Shunsuke Kuwahara ◽  
Masataka Watanabe ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Absolute Configuration ◽  
H Nmr

ChemInform Abstract: Absolute Configuration of Optical Isomers of 2-(4-Chlorobenzoylamino)- 3-(2(1H)-quinolinon-4-yl)propionic Acid (Rebamipide)

ChemInform ◽  
2010 ◽  
Vol 27 (21) ◽  
pp. no-no
Author(s):  
J. MATSUBARA ◽  
K. OTSUBO ◽  
S. MORITA ◽  
T. OHTANI ◽  
Y. KAWANO ◽  
...  
Keyword(s):  
Propionic Acid ◽  
Absolute Configuration ◽  
Optical Isomers
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