scholarly journals Epstein-Barr Virus-positive T-cell Lymphoproliferative Disease Following Umbilical Cord Blood Transplantation for Acute Myeloid Leukemia

2016 ◽  
Vol 83 (1) ◽  
pp. 35-42 ◽  
Author(s):  
Shunsuke Yui ◽  
Hiroki Yamaguchi ◽  
Ken-ichi Imadome ◽  
Ayako Arai ◽  
Mikiko Takahashi ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Epstein Barr Virus ◽  
Cord Blood Transplantation ◽  
Lymphoproliferative Disease ◽  
Umbilical Cord Blood Transplantation ◽  
Barr Virus ◽  
Blood Transplantation ◽  
Epstein Barr ◽  
Acute Myeloid

scholarly journals Spontaneous Epstein-Barr virus transformed B-cell line sharing the identical immunoglobulin gene rearrangement with acute myeloid leukemia

Blood ◽  
1989 ◽  
Vol 73 (3) ◽  
pp. 684-687 ◽  
Author(s):  
HH Gerhartz ◽  
CR Bartram ◽  
A Raghavachar ◽  
H Schmetzer ◽  
C Clemm ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
B Cell ◽  
Cell Line ◽  
Heavy Chain ◽  
Myeloid Leukemia ◽  
Epstein Barr Virus ◽  
Gene Rearrangement ◽  
Barr Virus ◽  
Epstein Barr ◽  
Acute Myeloid

Abstract Mononuclear cells from a 44-year-old patient with acute myeloid leukemia (AML) gave rise to a spontaneous permanent cell line cultured in suspension. The cell line was shown to be positive for Epstein-Barr virus nuclear antigen (EBNA). As expected, its composite phenotype was of B-cell type with B-cell antigens (CD 20, CD 21) and with monoclonal surface IgM of kappa type, but without detectable IgM secretion. Surprisingly, identical monoclonal rearrangements of the immunoglobulin heavy chain (JH) sequences could be demonstrated in the uncultured bone marrow AML cells and in the cell line that also had kappa light chain gene rearrangement. This is the first case to our knowledge of an EBNA positive B-cell line with identical monoclonal Ig heavy chain rearrangement as detected in myeloblastic leukemia cells.

Risk of Etoposide-Related Acute Myeloid Leukemia in the Treatment of Epstein-Barr Virus—Associated Hemophagocytic Lymphohistiocytosis

2002 ◽  
Vol 75 (2) ◽  
pp. 174-177 ◽  
Author(s):  
Shinsaku Imashuku ◽  
Tomoko Teramura ◽  
Kikuko Kuriyama ◽  
Junichi Kitazawa ◽  
Etsuro Ito ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Myeloid Leukemia ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Epstein Barr ◽  
Acute Myeloid
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