Simultaneous Spectrophotometric Determination of Tramadol and Acetaminophen in Pharmaceutical Formulations Using H-Point Standard Addition Method

2013 ◽  
Vol 6 (1) ◽  
pp. 48-55
Author(s):  
Ali Reza Zarei ◽  
Kobra Mardi ◽  
Soheila Chalavi
Keyword(s):  
Spectrophotometric Determination ◽  
Standard Addition ◽  
Pharmaceutical Formulations ◽  
Standard Addition Method ◽  
Addition Method

scholarly journals H-point Standard Addition Method for the Simultaneous Spectrophotometric Determination of Captopril and Hydrochlorothiazide in Pharmaceutical Formulations

2021 ◽  
pp. 77-85
Keyword(s):  
Spectrophotometric Determination ◽  
Standard Addition ◽  
Pharmaceutical Formulations ◽  
Standard Addition Method ◽  
Addition Method ◽  
Real Samples ◽  
Relative Standard ◽  
Recovery Percentage ◽  
Precision And Accuracy

Simultaneous spectrophotometric determination of captopril and hydro-chlorothiazide in pharmaceutical formulations by the H-point standard addition method (HPSAM) is described. Absorbance at 211.5 and 230.3 nm was monitored upon the addition of standard solutions of captopril. The results showed that in prepared mixtures, captopril and hydrochlorothiazide can be determined simultaneously at concentration ratios varying from 1.0:0.8 to 2.5:1.5 μg/mL, respectively. Percentage recovery was found to be 95.33–104.37% for captopril and 96.8–105% for hydrochlorothiazide, with a relative standard deviation (RSD) of 2.46%. The method was successfully used to evaluate the antihypertensive captopril drug in a binary combination of hydrochlorothiazide in real samples with high precision and accuracy within the recovery percentage.

Simultaneous Kinetic Spectrophotometric Determination of Ascorbic Acid and L-Cysteine by H-Point Standard Addition Method

2004 ◽  
Vol 148 (3-4) ◽  
pp. 259-265 ◽  
Author(s):  
Jahanbakhsh Ghasemi ◽  
Soodabe Seifi ◽  
Mozafar Sharifi ◽  
Rostam Ghorbani ◽  
Ali Amini
Keyword(s):  
Ascorbic Acid ◽  
Spectrophotometric Determination ◽  
Standard Addition ◽  
Standard Addition Method ◽  
Addition Method ◽  
Kinetic Spectrophotometric
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