Introduction. Acute bleeding from the upper gastrointestinal system is a
medical emergency which is followed by high mortality rate, ranging from 6 to
15% in spite of modern diagnostic methods and treatment. Bleeding from the
upper gastrointestinal system may be caused by gastrointestinal stromal
tumors of the stomach, which are mainly characterized by occult bleeding,
while profuse bleeding rarely occurs accompanied by hemorrhagic shock.
Gastrointestinal stromal tumors of stomach are the most common mesenchimal
tumors of the gastrointestinal tract. Case Report. In our study we showed a
60-year-old female patient with profuse bleeding from the stomach and the
clinical picture of severe hemorrhagic shock, caused by gastrointestinal
stromal tumor. An ovoid junction, raised towards the lumen, covered with
ulcerated mucosa in several places and followed by massive arterial bleeding
was found intraoperatively, after the performed gastrotomy. Histopathological
examination with immunohistochemical analysis confirmed that this was a
gastrointestinal stromal tumor of the stomach. Discussion. Acute bleeding
from the digestive system is a sudden and serious condition of the body.
Urgent esophagogastroduodenoscopy is a sensitive and specific diagnostic and
therapeutic method of choice. Massive bleeding from the upper
gastrointestinal tract is very rarely caused by gastrointestinal stromal
tumors, whose clinical picture is very heterogeneous and depends on tumor
size and location. Abundant bleeding from the tumor is an indication for
urgent surgical intervention. Conclusion. According to the literature massive
hemorrhage of the upper digestive system can rarely be caused by
gastrointestinal stromal tumor of the stomach. It is shown that abundant
hemorrhage of the upper digestive tract can be caused with gastric
gastrointestinal stromal tumor. Surgical resection is the main form of
treatment of gastrointestinal stromal tumors of the digestive system and
bleeding from these tumors caused by failure of endoscopic hemostasis.