scholarly journals Squamous cell carcinoma of unknown primary origin in a dog presenting with bone metastasis

2019 ◽  
Vol 81 (8) ◽  
pp. 1177-1181
Author(s):  
Oscar Rodrigo SIERRA MATIZ ◽  
Rafaela Bortolotti VIERA ◽  
Paulo Cesar JARK ◽  
Denner Santos DOS ANJOS ◽  
Julio Edward Hough MONTEIRO ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Lauren Chiec ◽  
Sadhna Verma ◽  
Ady Kendler ◽  
Nagla Abdel Karim

Pelvic squamous cell carcinoma of unknown primary origin has been described in several case reports of female patients. However, there have been no published reports describing male patients with pelvic squamous cell cancer of unknown primary origin. Our case describes a 52-year-old man who presented with right buttock pain, rectal urgency, and constipation. His physical examination demonstrated tenderness to palpation around his gluteal folds. Computed tomography scan of his abdomen and pelvis demonstrated a large mass in his retroperitoneum. The mass was determined to be squamous cell carcinoma of unknown primary origin. Additionally, the patient had small nodules in his right lower lung lobe and right hepatic lobe. The patient was treated with concomitant chemoradiation, including cisplatin and intensity-modulated radiation therapy, followed by carboplatin and paclitaxel. The patient achieved partial remission, in which he remained one year after his presentation. Our case is consistent with the literature which suggests that squamous cell carcinoma of unknown primary origin occurring outside of the head and neck region may have a more favorable prognosis than other carcinomas of unknown primary origin. Further studies are necessary to determine the most appropriate work-up, diagnosis, and optimal treatment strategies.



2020 ◽  
Vol 40 (8) ◽  
pp. 4207-4214
Author(s):  
MAXWELL Y. LEE ◽  
NICOLE FOWLER ◽  
DAVID ADELSTEIN ◽  
SHLOMO KOYFMAN ◽  
BRANDON PRENDES ◽  
...  


Head & Neck ◽  
2018 ◽  
Vol 41 (4) ◽  
pp. 1112-1121 ◽  
Author(s):  
Pasquale Di Maio ◽  
Oreste Iocca ◽  
Armando De Virgilio ◽  
Fabio Ferreli ◽  
Giovanni Cristalli ◽  
...  


2002 ◽  
Vol 27 (5) ◽  
pp. 385-386 ◽  
Author(s):  
HAKAN DEMIR ◽  
FATMA BERK ◽  
OKAN ERDINCLER ◽  
SERKAN ISGOREN ◽  
CUMALI AKTOLUN


2021 ◽  
Vol 6 (4) ◽  
pp. 441-447
Author(s):  
Eiman O.R Omar ◽  
Naik Haussein ◽  
Amal Ahmed

Background: Carcinoma of unknown primary origin (CUP) comprises various malignancies classified by detection of tissue-specific genes through immunohistochemistry (IHC). We aimed to explore the role of available immunohistochemical markers in diagnosing and classifying malignant neoplasms of unknown primary origin.Methods: A cross-sectional study included 141 patients diagnosed histologically as CUP and referred to the Histopathology and Immunohistochemistry Department, Khartoum Oncology Hospital, from 2012 to 2017. Hematoxylin and Eosin (H&E) and immune stained slides used in the workup were reviewed and classified into the main histologic types of CUP. Data were -analyzed by SPSS. Results: Out of 4436 cases, CUP represents (3.2%). The age group (60-69) years have the highest percentage (20.13%), with male predominance (51.77%). Lymph nodes represent (41.84%) followed by the liver (12.77%), spine (3.55%), and lungs (2.13%). Adenocarcinoma (75.89%) was the most common subtype, followed by undifferentiated neoplasm (14.18%), squamous cell carcinoma (7.09%), and carcinoma with neuroendocrine differentiation (2.84%). In 70 cases (49.6%) of the study cases, the primary site was determined, (17.7%) were given an only differential diagnosis, and in (32.6%) the origin remains unknown. Conclusions: CUP cases during the study period are infrequent (3.2%), and the primary origin was determined in nearly half of patients by the available immune markers. CUP’s common histological types were adenocarcinoma, undifferentiated neoplasm, squamous cell carcinoma, and carcinoma with neuroendocrine differentiation. The most common presenting sites were lymph node, liver, spine, and lungs.



Head & Neck ◽  
2017 ◽  
Vol 40 (2) ◽  
pp. 227-232 ◽  
Author(s):  
Allen M. Chen ◽  
Jessica Meshman ◽  
Sophia Hsu ◽  
Taeko Yoshizaki ◽  
Elliot Abemayor ◽  
...  


2018 ◽  
Vol 216 (5) ◽  
pp. 963-968
Author(s):  
Michael M. Wach ◽  
Elke van Beek ◽  
Reed Ayabe ◽  
Samantha Ruff ◽  
Zachary Brown ◽  
...  


Author(s):  
Alexandra N. De Leo ◽  
William M. Mendenhall ◽  
Roi Dagan ◽  
Kathryn E. Hitchcock ◽  
Peter T. Dziegielewski ◽  
...  


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