scholarly journals Bee Venom Pretreatment Has Both an Antinociceptive and Anti-Inflammatory Effect on Carrageenan-Induced Inflammation.

2001 ◽  
Vol 63 (3) ◽  
pp. 251-259 ◽  
Author(s):  
Jang-Hern LEE ◽  
Young-Bae KWON ◽  
Ho-Jae HAN ◽  
Woung-Chon MAR ◽  
Hye-Jung LEE ◽  
...  
Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 115-116
Author(s):  
Mohammad Nabiuni ◽  
Kazem Parivar ◽  
Bahman Zeynali ◽  
Azar Sheikholeslami ◽  
Latifeh Karimzadeh

Insects ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 297
Author(s):  
Hyun Seok Yun ◽  
Jisun Oh ◽  
Ji Sun Lim ◽  
Hyo Jung Kim ◽  
Jong-Sang Kim

The aim of this study was to compare the anti-inflammatory effect of wasp venom (WV) from the yellow-legged hornet (Vespa velutina) with that of bee venom (BV) on BV-2 murine microglial cells. WV was collected from the venom sac, freeze-dried, and used for in vitro examinations. WV and BV were non-toxic to BV-2 cells at concentrations of 160 and 12 µg/mL or lower, respectively. Treatment with WV reduced the secretion of nitric oxide and proinflammatory cytokines, including interleukin-6 and tumor necrosis factor alpha, from BV-2 cells activated by lipopolysaccharide (LPS). Western blot analysis revealed that WV and BV decreased the expression levels of inflammation markers, including inducible nitric oxide synthase and cyclooxygenase-2. In addition, WV decreased the nuclear translocation of nuclear factor κB (NF-κB), which is a key transcription factor in the regulation of cellular inflammatory response. Cumulatively, the results demonstrated that WV inhibited LPS-induced neuroinflammation in microglial cells by suppressing the NF-κB-mediated signaling pathway, which warrants further studies to confirm its therapeutic potential for neurodegenerative diseases.


2003 ◽  
Vol 15 (1) ◽  
pp. 93-96 ◽  
Author(s):  
Y.-B. Kwon ◽  
H.-W. Kim ◽  
T.-W. Ham ◽  
S.-Y. Yoon ◽  
D.-H. Roh ◽  
...  

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Eun Jin Yang ◽  
Jing Hua Jiang ◽  
Sang Min Lee ◽  
Myeong Soo Lee ◽  
Sun Mi Choi

2008 ◽  
Vol 430 (2) ◽  
pp. 163-168 ◽  
Author(s):  
Seo-Yeon Yoon ◽  
Young-Bae Kwon ◽  
Hyun-Woo Kim ◽  
Dae-Hyun Roh ◽  
Hyoung-Sig Seo ◽  
...  

2005 ◽  
Vol 1049 (2) ◽  
pp. 210-216 ◽  
Author(s):  
Seo-Yeon Yoon ◽  
Hyun-Woo Kim ◽  
Dae-Hyun Roh ◽  
Young-Bae Kwon ◽  
Tae-Oh Jeong ◽  
...  

Author(s):  
Seung‑Heon Shin ◽  
Mi‑Kyung Ye ◽  
Sung‑Yong Choi ◽  
Kwan‑Kyu Park

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