Metastatic spinal cord compression

2020 ◽  
Vol 81 (4) ◽  
pp. 1-10
Author(s):  
Surendra Patnaik ◽  
Joseph Turner ◽  
Praveen Inaparthy ◽  
Will KM Kieffer
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cauda Equina ◽  
Spinal Column ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Neurological Injury ◽  
Clinical Approach ◽  
Mobility Function ◽  
Ongoing Development

Metastatic spinal cord compression is compression of the spinal cord or cauda equina as a result of metastatic deposits in the spinal column. It affects approximately 4000 cases per year in England and Wales. Prompt identification and treatment of metastatic spinal cord compression is necessary to prevent irreversible neurological injury, treat pain and maintain patients' mobility, function and independence. Survival of patients with common malignancies has improved significantly with the ongoing development of radiotherapy and chemotherapy, as well as improved surgical treatment of resectable primary tumours. This article outlines the clinical approach to presentation, pathophysiology, diagnosis and management.

scholarly journals Laminectomy without instrumentation for surgical treatment of metastatic spinal cord compression

2014 ◽  
Vol 13 (1) ◽  
pp. 63-66 ◽  
Author(s):  
Paulo Alvim Borges ◽  
William Gemio Jacobsen Teixeira ◽  
Douglas Kenji Narazaki ◽  
Alexandre Fogaça Cristante ◽  
Cesar Salge Ghilardi ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cauda Equina ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Safe Procedure ◽  
Mechanical Instability ◽  
Metastatic Tumors ◽  
Record Review

OBJECTIVE: To analyze the development of mechanical complications as a result of spinal decompression or cauda equina in patients with metastatic tumors of the spine via laminectomy or laminoartrectomy without fixation. METHODS: We studied the medical records of all patients submitted to spine decompression with laminectomy without fixation. The decompression was indicated to treat cord compression or cauda equina caused by metastatic tumors. Patients were evaluated for the development of postoperative mechanical instability by comparing the preoperative radiological examinations with the latest one available in the medical record review.. In these images, we evaluated the emergence of new deformity in the sagittal or coronal planes and translational deformity. We consider new deformity, signs of deformity greater or equal to 5° in the coronal or sagittal planes and signs of increased vertebral translation greater than or equal to 3 mm. RESULTS: No patient developed radiological instability in the period evaluated with an average follow-up of 163.24 days (3-663). The complication rate in our sample was not higher than the previously reported in the literature. CONCLUSION: Isolated laminectomy at one or more levels is a safe procedure for the treatment of metastatic spinal cord compression where the spine is judged stable before surgery.

Radiotherapy of metastatic spinal cord compression in very elderly patients

2007 ◽  
Vol 67 (1) ◽  
pp. 256-263 ◽  
Author(s):  
Dirk Rades ◽  
Peter J. Hoskin ◽  
Johann H. Karstens ◽  
Volker Rudat ◽  
Theo Veninga ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Elderly Patients ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Very Elderly

Audit of metastatic spinal cord compression

2016 ◽  
Vol 28 ◽  
pp. S2
Author(s):  
A. Cole ◽  
J. O'Hare ◽  
K. Harpur ◽  
C. O'Brien ◽  
N. Evans ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression

Thoracic spinal cord compression masquerading as cauda equina syndrome

2016 ◽  
Vol 34 (4) ◽  
pp. 756.e3-756.e5 ◽  
Author(s):  
Katherine Stolper ◽  
Erin R. Hanlin ◽  
Michael D. April ◽  
John L. Ritter ◽  
Curtis J. Hunter ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cauda Equina Syndrome ◽  
Cauda Equina ◽  
Cord Compression ◽  
Thoracic Spinal Cord ◽  
Thoracic Spinal

scholarly journals Effectiveness of radiotherapy for metastatic spinal cord compression in patients with short life expectancy

2017 ◽  
Vol 22 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Alexandra Giraldo ◽  
Sergi Benavente ◽  
Mónica Ramos ◽  
Ramona Vergés ◽  
Odimar Coronil ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Life Expectancy ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Short Life ◽  
Short Life Expectancy

Developing an early alert system for metastatic spinal cord compression (MSCC): Red Flag credit cards

2013 ◽  
Vol 16 (01) ◽  
pp. 14-20 ◽  
Author(s):  
Jackie Turnpenney ◽  
Sue Greenhalgh ◽  
Lena Richards ◽  
Annamaria Crabtree ◽  
James Selfe
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Credit Cards ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
Alert System ◽  
Red Flag ◽  
Early Alert

115 An Audit on Dexamethasone Prescribing Practice on Surgically Managed Metastatic Spinal Cord Compression Patients in the Manchester Centre for Clinical Neurosciences: Lessons Learned in Closing the Loop

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
R Laurente ◽  
R Mohammed ◽  
M Elmalky
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Compression ◽  
Cord Compression ◽  
Lessons Learned ◽  
Metastatic Spinal Cord Compression ◽  
Loading Dose ◽  
The Past ◽  
Prescribing Practice ◽  
Closing The Loop ◽  
Almost All

Abstract Metastatic Spinal Cord Compression is a surgical emergency owing to its propensity to cause significant morbidity and mortality. Dexamethasone is prescribed to reduce oedema and promote vascular membrane stabilization. The is done so until a more definitive management has been performed. This is a retrospective study evaluating the steroid-prescribing practice for MSCC patients in 2018 at a tertiary spinal unit in Greater Manchester. Thirty-three patients who underwent stabilisation were evaluated in terms of both steroid prescribing and weaning practices. Standards used against for both were the NICE guidelines and the Edinburgh/Christie’s guidelines. Of the 33 patients evaluated, only 1 patient received the correct loading dose of 16mg, whilst 27 went straight to being given 8mg BD. 5 did not receive dexamethasone at all. In terms of discontinuation/weaning, 26 were weaned accordingly and 2 were not weaned to continue as adjuvant treatment. Dexamethasone prescribing practises has since improved over the past two years. 93% of the patients have been correctly weaned as compared to 38% in the past. In terms of prescription, much needs to be done as almost all the patients evaluated did not get the correct loading dose despite receiving the appropriate maintenance.

Four cases of spinal cord compression: The need for early diagnosis

1985 ◽  
Vol 71 (2) ◽  
pp. 92-95
Author(s):  
R. K. Bradley ◽  
S. H. Murch
Keyword(s):  
Spinal Cord ◽  
Early Diagnosis ◽  
Clinical Diagnosis ◽  
Spinal Cord Compression ◽  
Cauda Equina ◽  
Cord Compression ◽  
Symptoms And Signs

SummaryFour cases of spinal cord compression, with symptoms and signs evolving over several years or as quickly as two days, are presented. The symptoms and signs of extrinsic cord compression are described and briefly contrasted with those of intrinsic cord or cauda equina lesions. The need for early clinical diagnosis is emphasised.

OC-0408 Higher-dose radiotherapy for metastatic spinal cord compression: First results of a phase II trial

2021 ◽  
Vol 161 ◽  
pp. S303-S304
Author(s):  
D. Rades ◽  
C. Staackmann ◽  
D. Lomidze ◽  
D. Lomidze ◽  
N. Jankarashvili ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Phase Ii ◽  
Spinal Cord Compression ◽  
Phase Ii Trial ◽  
Cord Compression ◽  
Metastatic Spinal Cord Compression ◽  
First Results
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