scholarly journals Preliminary in vitro Study on Enhancement of Bone-like Hydroxyapatite Formation on Bio-active Titanium Alloy by Low-intensity Pulsed Ultrasound Waving for Early Bone Bonding

2010 ◽  
Vol 5 (4) ◽  
pp. 449-460
Author(s):  
Masanori KOBAYASHI ◽  
Keisuke NODA ◽  
Naohiro TATEMATSU
Keyword(s):  
Titanium Alloy ◽  
In Vitro Study ◽  
Vitro Study ◽  
Pulsed Ultrasound ◽  
Low Intensity Pulsed Ultrasound ◽  
Low Intensity ◽  
Hydroxyapatite Formation

Effect of low-intensity pulsed ultrasound on the activity of osteoclasts: An in vitro study

2016 ◽  
Vol 70 ◽  
pp. 73-78 ◽  
Author(s):  
Murilo Fernando Neuppmann Feres ◽  
Cezary Kucharski ◽  
Samira Diar-Bakirly ◽  
Tarek El-Bialy
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Pulsed Ultrasound ◽  
Low Intensity Pulsed Ultrasound ◽  
Low Intensity

scholarly journals Development and Validation of Low-Intensity Pulsed Ultrasound Systems for Highly Controlled in vitro Cell Stimulation

Ultrasonics ◽  
2021 ◽  
pp. 106495
Author(s):  
F. Fontana ◽  
F. Iberite ◽  
A. Cafarelli ◽  
A. Aliperta ◽  
G. Baldi ◽  
...  
Keyword(s):  
Pulsed Ultrasound ◽  
Cell Stimulation ◽  
Low Intensity Pulsed Ultrasound ◽  
Low Intensity ◽  
Development And Validation

scholarly journals Low-Intensity Pulsed Ultrasound Promotes Autophagy-Mediated Migration of Mesenchymal Stem Cells and Cartilage Repair

2021 ◽  
Vol 30 ◽  
pp. 096368972098614
Author(s):  
Peng Xia ◽  
Xinwei Wang ◽  
Qi Wang ◽  
Xiaoju Wang ◽  
Qiang Lin ◽  
...  
Keyword(s):  
Cartilage Repair ◽  
Matrix Protein ◽  
Extracellular Matrix Protein ◽  
Histopathological Analysis ◽  
Pulsed Ultrasound ◽  
Low Intensity Pulsed Ultrasound ◽  
Low Intensity ◽  
Autophagy Inhibitor

Mesenchymal stem cell (MSC) migration is promoted by low-intensity pulsed ultrasound (LIPUS), but its mechanism is unclear. Since autophagy is known to regulate cell migration, our study aimed to investigate if LIPUS promotes the migration of MSCs via autophagy regulation. We also aimed to investigate the effects of intra-articular injection of MSCs following LIPUS stimulation on osteoarthritis (OA) cartilage. For the in vitro study, rat bone marrow-derived MSCs were treated with an autophagy inhibitor or agonist, and then they were stimulated by LIPUS. Migration of MSCs was detected by transwell migration assays, and stromal cell-derived factor-1 (SDF-1) and C-X-C chemokine receptor type 4 (CXCR4) protein levels were quantified. For the in vivo study, a rat knee OA model was generated and treated with LIPUS after an intra-articular injection of MSCs with autophagy inhibitor added. The cartilage repair was assessed by histopathological analysis and extracellular matrix protein expression. The in vitro results suggest that LIPUS increased the expression of SDF-1 and CXCR4, and it promoted MSC migration. These effects were inhibited and enhanced by autophagy inhibitor and agonist, respectively. The in vivo results demonstrate that LIPUS significantly enhanced the cartilage repair effects of MSCs on OA, but these effects were blocked by autophagy inhibitor. Our results suggest that the migration of MSCs was enhanced by LIPUS through the activation autophagy, and LIPUS improved the protective effect of MSCs on OA cartilage via autophagy regulation.

scholarly journals Long-term antibacterial properties of a nanostructured titanium alloy surface: An in vitro study

2022 ◽  
Vol 13 ◽  
pp. 100176
Author(s):  
Richard Bright ◽  
Daniel Fernandes ◽  
Jonathan Wood ◽  
Dennis Palms ◽  
Anouck Burzava ◽  
...  
Keyword(s):  
Titanium Alloy ◽  
Antibacterial Properties ◽  
In Vitro Study ◽  
Vitro Study ◽  
Alloy Surface ◽  
Nanostructured Titanium

Low-Intensity Pulsed Ultrasound Stimulates Osteogenic Differentiation of Periosteal Cells In Vitro

2020 ◽  
Author(s):  
Wai Myo Maung ◽  
Hidemi Nakata ◽  
Motoi Miura ◽  
Munemitsu Miyasaka ◽  
You-Kyoung Kim ◽  
...  
Keyword(s):  
Osteogenic Differentiation ◽  
Pulsed Ultrasound ◽  
Low Intensity Pulsed Ultrasound ◽  
Low Intensity ◽  
Periosteal Cells
Sign in / Sign up

Export Citation Format

Share Document