Quantitative evaluation of human erythrocyte deformability by using a sheath flow micro-channel

2018 ◽  
Vol 2018.30 (0) ◽  
pp. 1F11
Author(s):  
Tomoyuki Inui ◽  
Tsutomu Tajikawa ◽  
Toshiyuki Ikemoto ◽  
Tohru Takeuchi
Keyword(s):  
Quantitative Evaluation ◽  
Human Erythrocyte ◽  
Erythrocyte Deformability ◽  
Micro Channel ◽  
Sheath Flow

scholarly journals Investigation of Optimal Coupling Velocities of the Sample and Sheath Flows for Hydrodynamic Focusing

2020 ◽  
Vol 8 (8) ◽  
pp. 601
Author(s):  
Dingpeng Huang ◽  
Hangzhou Wang ◽  
Xiaoping Wang ◽  
Kan Guo ◽  
Zhuoli Yuan ◽  
...  
Keyword(s):  
General Framework ◽  
Imaging System ◽  
Independent Experiment ◽  
Micro Channel ◽  
Hydrodynamic Focusing ◽  
Microscopic Imaging ◽  
Sheath Flow ◽  
Optimal Coupling ◽  
Working Efficiency

Focusing performance is a major concern for systems based on hydrodynamic focusing. In this study, the hydrodynamic focusing subsystem of a microscopic imaging system was analysed and modelled. The theoretical model was used to analyse the velocity and distribution range of sample particles in the focused sample flow in the micro-channel of the hydrodynamic focusing subsystem, when the velocities of the sample and sheath flows were varied. The results were used to optimise the coupling velocities of the sample and sheath flows for the microscopic imaging system, to keep working efficiency and image quality of the system simultaneously. An independent experiment was then conducted for verification, and the results agreed well with the theoretical investigation. The results of this study provide a general framework for adjusting the sample and sheath flow velocities to optimise the hydrodynamic focusing performance.

Sign in / Sign up

Export Citation Format

Share Document