The performance of the epileptogenic discharge suppression of the focal cortical cooling device

Author(s):  
Jouji UCHIYAMA ◽  
Kimihiko NAKANO ◽  
Takashi SAITO ◽  
Hirochika IMOTO ◽  
Masami FUJII ◽  
...  
2006 ◽  
Vol 72 (718) ◽  
pp. 1921-1926 ◽  
Author(s):  
Joji UCHIYAMA ◽  
Kimihiko NAKANO ◽  
Takashi SAITO ◽  
Masami FUJII ◽  
Nobuhiro TANAKA ◽  
...  

Author(s):  
Joji UCHIYAMA ◽  
Kimihiko NAKANO ◽  
Takashi SAITO ◽  
Hirochika IMOTO ◽  
Nobuhiro TANAKA ◽  
...  

Author(s):  
Masayuki YAMAMOTO ◽  
Jouji UCHIYAMA ◽  
Kimihiko NAKANO ◽  
Takashi SAITO ◽  
Hirochika IMOTO ◽  
...  

2004 ◽  
Author(s):  
Simon S. Ang ◽  
Paneer Selvam ◽  
Ajay Malshe ◽  
Fred Barlow

2019 ◽  
Vol 14 (1) ◽  
pp. 66-71 ◽  
Author(s):  
Tiziana Prochilo ◽  
Alessandra Huscher ◽  
Federica Andreis ◽  
Mara Mirandola ◽  
Elisabetta Zaina ◽  
...  

Background: The most effective agents in the treatment of breast cancer have a common side effect, the hair loss. Some studies reported a reduction of hair loss with the use of the scalp cooling device. Indeed, it decreases the drug accumulation in the hair follicles. We report our preliminary experience with a scalp cooling device in reducing chemotherapy-induced alopecia and related distress in breast cancer patients undergoing adjuvant chemotherapy. </P><P> Methods: Hair loss grading and treatment tolerability were evaluated during chemotherapy every 21 days and 3 weeks after the last cycle of chemotherapy via Dean’s scale by patients and operators and a comfort analogic scale by patients. We administered the Hospital Anxiety and Depression Scale questionnaire at the baseline and at the end of treatment to assess the distress related to chemotherapy- induced alopecia. Results: Among the 46 patients identified, 27 accepted the device. The eligible chemotherapy regimens included docetaxel+cyclophosphamide (TC), doxorubicin+cyclophosphamide (AC) and paclitaxel (P) weekly+trastuzumab (T). 24 pts (89%) completed the treatment; 3 pts (11%) treated with AC prematurely interrupted use of the scalp-cooling device due to inefficacy. After the last cycle of chemotherapy, the number of patient who perceived a HL < grade 2 was 16 (59%). The hair retention reported by operators has been higher (78%). 81.5% of patients well tolerated the treatment. Conclusion: In our study, the scalp-cooling device reduced chemotherapy-induced alopecia in taxane- based chemotherapy. Furthermore, it suggests a discordance in hair loss perception between patients and operators.


2021 ◽  
Vol 162 ◽  
pp. 106761
Author(s):  
Jing Wang ◽  
Jiang-bo Wang ◽  
Zhong-yi Long ◽  
Tao Zhu ◽  
Zheng-sheng Li ◽  
...  

Materials ◽  
2021 ◽  
Vol 14 (13) ◽  
pp. 3734
Author(s):  
Jianyu Yang ◽  
Xudong Li ◽  
Fei Li ◽  
Wenxiao Wang ◽  
Zhijie Li ◽  
...  

The finite element model (FE) of temperature field of straight thin-walled samples in laser cladding IN718 was established, and the growth of microstructure was simulated by cellular automata (CA) method through macro-micro coupling (CA-FE). The effects of different cooling conditions on microstructure, hardness, and properties of laser-cladding layer were studied by designing cooling device. The results show that the simulation results are in good agreement with the microstructure of the cladding layer observed by the experiment. With the scanning strategy of reducing laser power layer-by-layer, the addition of water cooling device and the processing condition of 0.7 mm Z-axis lift, excellent thin-walled parts can be obtained. With the increase of cladding layers, the pool volume increases, the temperature value increases, the temperature gradient, cooling rate, solidification rate, K value gradually decrease, and eventually tend to be stable, in addition, the hardness shows a fluctuating downward trend. Under the processing conditions of layer-by-layer power reduction and water cooling device, the primary dendrite arm spacing reduced to about 8.3 μm, and the average hardness at the bottom of cladding layer increased from 260 HV to 288 HV. The yield strength and tensile strength of the tensile parts prepared under forced water cooling increased to a certain extent, while the elongation slightly decreased.


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