Effects of age-related changes in lower limb skeletal muscles on human gait: A forward dynamic simulation study

2017 ◽  
Vol 2017.92 (0) ◽  
pp. M421
Author(s):  
Tatsuya Arakawa ◽  
Tomohiro Otani ◽  
Yo Kobayashi ◽  
Masao Tanaka
Keyword(s):  
Dynamic Simulation ◽  
Simulation Study ◽  
Lower Limb ◽  
Skeletal Muscles ◽  
Human Gait ◽  
Age Related ◽  
Age Related Changes

scholarly journals Losing touch: age-related changes in plantar skin sensitivity, lower limb cutaneous reflex strength, and postural stability in older adults

2016 ◽  
Vol 116 (4) ◽  
pp. 1848-1858 ◽  
Author(s):  
Ryan M. Peters ◽  
Monica D. McKeown ◽  
Mark G. Carpenter ◽  
J. Timothy Inglis
Keyword(s):  
Older Adults ◽  
Lower Limb ◽  
Postural Stability ◽  
Tibialis Anterior ◽  
Tibialis Anterior Muscle ◽  
Quiet Standing ◽  
Detection Thresholds ◽  
Cutaneous Reflex ◽  
Age Related ◽  
Age Related Changes

Age-related changes in the density, morphology, and physiology of plantar cutaneous receptors negatively impact the quality and quantity of balance-relevant information arising from the foot soles. Plantar perceptual sensitivity declines with age and may predict postural instability; however, alteration in lower limb cutaneous reflex strength may also explain greater instability in older adults and has yet to be investigated. We replicated the age-related decline in sensitivity by assessing monofilament and vibrotactile (30 and 250 Hz) detection thresholds near the first metatarsal head bilaterally in healthy young and older adults. We additionally applied continuous 30- and 250-Hz vibration to drive mechanically evoked reflex responses in the tibialis anterior muscle, measured via surface electromyography. To investigate potential relationships between plantar sensitivity, cutaneous reflex strength, and postural stability, we performed posturography in subjects during quiet standing without vision. Anteroposterior and mediolateral postural stability decreased with age, and increases in postural sway amplitude and frequency were significantly correlated with increases in plantar detection thresholds. With 30-Hz vibration, cutaneous reflexes were observed in 95% of young adults but in only 53% of older adults, and reflex gain, coherence, and cumulant density at 30 Hz were lower in older adults. Reflexes were not observed with 250-Hz vibration, suggesting this high-frequency cutaneous input is filtered out by motoneurons innervating tibialis anterior. Our findings have important implications for assessing the risk of balance impairment in older adults.

scholarly journals Age-related changes in myostatin expression in rat skeletal muscles

2018 ◽  
Vol 7 (4) ◽  
pp. 221-227 ◽  
Author(s):  
Tsubasa Shibaguchi ◽  
Takeshi Maeoka ◽  
Toshinori Yoshihara ◽  
Hisashi Naito ◽  
Katsumasa Goto ◽  
...  
Keyword(s):  
Skeletal Muscles ◽  
Age Related ◽  
Age Related Changes

scholarly journals Age-related changes in the mechanical properties of the epimysium in skeletal muscles of rats

2008 ◽  
Vol 41 (2) ◽  
pp. 465-469 ◽  
Author(s):  
Yingxin Gao ◽  
Tatiana Y. Kostrominova ◽  
John A. Faulkner ◽  
Alan S. Wineman
Keyword(s):  
Mechanical Properties ◽  
Skeletal Muscles ◽  
Age Related ◽  
Age Related Changes

scholarly journals AGE-RELATED CHANGES IN THE STRUCTURE AND FUNCTION OF SKELETAL MUSCLES

2007 ◽  
Vol 34 (11) ◽  
pp. 1091-1096 ◽  
Author(s):  
John A Faulkner ◽  
Lisa M Larkin ◽  
Dennis R Claflin ◽  
Susan V Brooks
Keyword(s):  
Skeletal Muscles ◽  
Structure And Function ◽  
Age Related ◽  
And Function ◽  
Age Related Changes

Age-related changes of aqueous protein profiles in rat fast and slow twitch skeletal muscles

2000 ◽  
Vol 21 (2) ◽  
pp. 465-472 ◽  
Author(s):  
Dongqing Cai ◽  
Ming Li ◽  
Kwongman Lee ◽  
Kaho Lee ◽  
Wannar Wong ◽  
...  
Keyword(s):  
Skeletal Muscles ◽  
Protein Profiles ◽  
Age Related ◽  
Slow Twitch ◽  
Age Related Changes

DIFFERENTIAL AGE-RELATED CHANGES IN MOTOR UNIT PROPERTIES IN TWO MUSCLES OF THE HUMAN LOWER LIMB.

1998 ◽  
Vol 30 (Supplement) ◽  
pp. 205
Author(s):  
J. M. Jakobi ◽  
D. M. Connelly ◽  
M. R. Roos ◽  
A. A. Vandervoort ◽  
C. L. Rice
Keyword(s):  
Motor Unit ◽  
Lower Limb ◽  
Age Related ◽  
Age Related Changes
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