scholarly journals Isolated neutropenia caused by copper deficiency due to jejunal feeding and excessive zinc intake: A case report

2021 ◽  
Vol 9 (29) ◽  
pp. 8825-8830
Author(s):  
Hiromitsu Ohmori ◽  
Hiroko Kodama ◽  
Masahiko Takemoto ◽  
Masami Yamasaki ◽  
Tomio Matsumoto ◽  
...  
2021 ◽  
Vol 4 (6) ◽  
pp. 27188-27194
Author(s):  
Louise Azevedo Lobo- Lopes ◽  
Sebastião Eurico de Melo- Souza ◽  
Vicente Mamede de Arruda Filho ◽  
Marco Aurélio Fraga Borges

Copper is an essential enzymatic cofactor in many stages of normal functioning of human body, acting mainly in hematological, vascular and neurological functions. Its deficiency is linked to some conditions as highly isolated oral zinc intake, parenteral nutrition and after bariatric surgery. Neurological symptoms due copper deficiency include gait abnormalities, sensitive ataxia and sensitive neuropathic symptoms. We present a case of copper deficiency myelopathy after bariatric surgery. Copper deficiency myelopathy is poorly diagnosed, being imperative the early recognition of the condition aiming better outcomes and neurological recovery.


2008 ◽  
Vol 65 (2) ◽  
pp. 464-466 ◽  
Author(s):  
Rungsinee A. Liusuwan ◽  
Tina Palmieri ◽  
Nancy Warden ◽  
David G. Greenhalgh

2016 ◽  
Vol 60 (No. 9) ◽  
pp. 522-526 ◽  
Author(s):  
G. Vengust ◽  
T. Svara ◽  
M. Goc ◽  
D. Zele

PM&R ◽  
2009 ◽  
Vol 1 ◽  
pp. S252-S252
Author(s):  
Sarah K. Cederholm ◽  
Michael J. Gruba ◽  
Jeffrey A. Strommen

PM&R ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 554-557
Author(s):  
Kevin Huang ◽  
Debbie Lee ◽  
Benjamin Ingraham ◽  
Tarek A. Hijaz ◽  
Alan S. Anschel

2018 ◽  
Vol 52 (4) ◽  
pp. 183-189
Author(s):  
Takato Sasaki ◽  
Kouji Masumoto ◽  
Takahiro Aoyama ◽  
Touko Shinkai

2021 ◽  
Author(s):  
Paulo de Lima Serrano ◽  
Igor Braga Farias ◽  
Bruno de Mattos Lombardi Badia ◽  
José Marcos Vieira de Albuquerque Filho ◽  
Paulo Victor Sgobbi de Souza ◽  
...  

Introduction: The performance of bariatric surgeries has increased in recente years. Secondary mal- absorptive syndrome is an important cause of acquired copper deficiency, especially after Roux-em-Y gastric by-pass. The clinical manifestation of this deficiency disorder can occur years or decades after the surgery. Objective: To describe the course, clinical manifestations, therapeutic approaches and to raise concern about acquired copper deficiency in patients who underwent bariatric surgery. Methods: A case report seen in the neuromuscular service of the federal university of São Paulo.SP. Results: The patient underwent Roux-en-Y gastrojejunostomy in 2010, 6 years before the initial manifestations of paresthesia on the lower limbs and anemia. The symptons progressed to imbalance and falls. Magnetic resonance image depicted T2 hyperintense signal in the posterior column from C4- T4. A Vitamin B12 deficiency was considered to be the cause but intramuscular therapy was ineffective. The neurological condition deteriorated and the patient was unable to walk without a walker. A severe copper deficiency was diagnosed but oral and intravenous replacement did not improve the clinical picture. Only after reversion of the Roux-em-Y gastric by-pass that the patient improved. Conclusion: Obesity is growing health problem and the incidence of bariatric surgery is increasing. Acquire copper deficiency should always be on mind when facing a patient with myeloneuropathy that underwent these group of surgeries. Rapidly installed therapeutic approach can prevent neurological sequelae.


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