scholarly journals A comparison of the voice difference of persons with Idiopathic Parkinson's disease and a normal group in five vowels

2012 ◽  
Vol 4 (1) ◽  
pp. 119-124 ◽  
Author(s):  
In-Ae Lee ◽  
Moon-Jeoung Kim ◽  
Young-Jin Hwang
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Normal Group ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease ◽  
The Voice

scholarly journals Idiopathic Parkinson's disease: vocal and quality of life analysis

2012 ◽  
Vol 70 (9) ◽  
pp. 674-679 ◽  
Author(s):  
Luiza Furtado e Silva ◽  
Ana Cristina Côrtes Gama ◽  
Francisco Eduardo Costa Cardoso ◽  
César Augusto da Conceição Reis ◽  
Iara Barreto Bassi
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Fundamental Frequency ◽  
Control Group ◽  
Idiopathic Parkinson’S Disease ◽  
Self Perception ◽  
Idiopathic Parkinson's Disease ◽  
The Voice

OBJECTIVE: To compare voice and life quality of male patients with idiopathic Parkinson's disease, with individuals without disease (Control Group). METHODS: A cross-sectional study that evaluated the voice of individuals with Parkinson's disease, the group was composed of 27 subjects, aged from 39 to 79 years-old (average 59.96). The Control Group was matched on sex and age. Participants underwent voice recording. Perceptual evaluation was made using GRBASI scale, which considers G as the overall degree of dysphonia, R as roughness, B as breathiness, A as asthenia, S as strain and I as instability. The acoustic parameters analyzed were: fundamental frequency, jitter, shimmer, and harmonic to noise ratio (NHR). For vocal self-perception analysis, we used the Voice Related Quality of Life protocol. RESULTS: Fundamental frequency and jitter presented higher values in the Parkinson's group. NHR values were higher in the Control Group. Perceptual analysis showed a deviation ranging. The vocal disorder self-perception demonstrated a worse impact on quality of life. CONCLUSIONS: Individuals with Parkinson's disease have an altered voice quality and a negative impact on quality of life.

Pursuing Multiple Biomarkers for Early Idiopathic Parkinson’s Disease Diagnosis

2021 ◽  
Author(s):  
Yareth Gopar-Cuevas ◽  
Ana P. Duarte-Jurado ◽  
Rosa N. Diaz-Perez ◽  
Odila Saucedo-Cardenas ◽  
Maria J. Loera-Arias ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Diagnosis ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease ◽  
Multiple Biomarkers

scholarly journals High-resolution ultrasound changes of the vagus nerve in idiopathic Parkinson’s disease (IPD): a possible additional index of disease

2021 ◽  
Author(s):  
F. Sartucci ◽  
T. Bocci ◽  
M. Santin ◽  
P. Bongioanni ◽  
G. Orlandi
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
High Resolution ◽  
Vagus Nerve ◽  
Imaging Modality ◽  
Disease Stage ◽  
Motor Nucleus ◽  
Idiopathic Parkinson’S Disease ◽  
Idiopathic Parkinson's Disease ◽  
Additional Index

Abstract Background and rationale Histopathological studies revealed degeneration of the dorsal motor nucleus of the vagus nerve (VN) early in the course of idiopathic Parkinson’s disease (IPD). Degeneration of VN axons should be detectable by high-resolution ultrasound (HRUS) as a thinning of the nerve trunk. In order to establish if the VN exhibits sonographic signs of atrophy in IPD, we examined patients with IPD compared with age-matched controls. Material and methods We measured the caliber (cross-sectional area, CSA) and perimeter of the VN in 20 outpatients with IPD (8 females and 12 males; mean age 73.0 + 8.6 years) and in age-matched controls using HRUS. Evaluation was performed by blinded raters using an Esaote MyLab Gamma device in conventional B-Mode with an 8–19 MHz probe. Results In both sides, the VN CSA was significantly smaller in IPD outpatients than in controls (right 2.37 + 0.91, left 1.87 + 1.35 mm2 versus 6.0 + 1.33, 5.6 + 1.26 mm2; p <0.001), as well as the perimeter (right 5.06 + 0.85, left 4.78 + 1.74 mm versus 8.87 + 0.86, 8.58 + 0.97 mm; p <0.001). There were no significant correlations between VN CSA and age, the Hoehn and Yahr scale, L-dopa therapy, and disease duration. Conclusion Our findings provide evidence of atrophy of the VNs in IPD patients by HRUS. Moreover, HRUS of the VN represent a non-invasive easy imaging modality of screening in IPD patients independent of disease stage and duration and an interesting possible additional index of disease.

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