Newer developments in viral hepatitis: Looking beyond hepatotropic viruses

Manasvi Gupta; Gaurav Manek; Kaitlyn Dombrowski; Rakhi Maiwall

doi:10.13105/wjma.v9.i6.522

Newer developments in viral hepatitis: Looking beyond hepatotropic viruses

World Journal of Meta-Analysis ◽

10.13105/wjma.v9.i6.522 ◽

2021 ◽

Vol 9 (6) ◽

pp. 522-542

Author(s):

Manasvi Gupta ◽

Gaurav Manek ◽

Kaitlyn Dombrowski ◽

Rakhi Maiwall

Keyword(s):

Viral Hepatitis

Download Full-text

Viral hepatitis: an occupational hazard of medical personnel. Experience of the Yalenew Haven Hospital, 1952 to 1965

JAMA ◽

10.1001/jama.195.5.362 ◽

1966 ◽

Vol 195 (5) ◽

pp. 362-364 ◽

Cited By ~ 11

Author(s):

E. B. Byrne

Keyword(s):

Viral Hepatitis ◽

Medical Personnel ◽

Occupational Hazard ◽

Haven Hospital

Download Full-text

Qualitative study on “hydropic degeneration” of The hepatocytes in viral hepatitis

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010016039x ◽

1990 ◽

Vol 48 (3) ◽

pp. 568-569

Author(s):

Le Meizhao ◽

Ye Ming ◽

Song Xiaoming ◽

Xu Jiazhang

Keyword(s):

Qualitative Study ◽

Viral Hepatitis ◽

Chronic Active Hepatitis ◽

Microscopic Observation ◽

Hydropic Degeneration ◽

Light Microscopic Observation ◽

Biopsy Specimens ◽

Endoplasm Reticulum ◽

Mixed Fluid ◽

Peripheral Cytoplasm

“Hydropic degeneration” of the hepatocytes are often found in biopsy of the liver of some kinds of viral hepatitis. Light microscopic observation, compareted with the normal hepatocytes, they are enlarged, sometimes to a marked degree when the term “balloning” degeneration is used. Their cytoplasm rarefied, and show some clearness in the peripheral cytoplasm, so, it causes a hydropic appearance, the cytoplasm around the nuclei is granulated. Up to the present, many studies belive that main ultrastructural chenges of hydropic degeneration of the hepatocytes are results of the RER cristae dilatation with degranulation and disappearance of glycogen granules.The specimens of this study are fixed with the mixed fluid of the osmium acidpotassium of ferricyanide, Epon-812 embed. We have observed 21 cases of biopsy specimens with chronic severe hepatitis and severe chronic active hepatitis, and found that the clear fields in the cytoplasm actually are a accumulating place of massive glycogen. The granules around the nuclei are converging mitochondria, endoplasm reticulum and other organelles.

Download Full-text