scholarly journals Epidemiological, cytogenetic and clinical characteristics of children with Down syndrome in eastern Croatia – fifteen-year postnatal experience

2021 ◽  
Vol 65 (2) ◽  
Author(s):  
Višnja Tomac ◽  
Silvija Pušeljić ◽  
Martina Kos ◽  
Sanja Dorner ◽  
Romana Pavišić Kezan ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Clinical Characteristics ◽  
Children With Down Syndrome

Demographic and Clinical Characteristics Associated With Adherence to Guideline-Based Polysomnography in Children With Down Syndrome

2020 ◽  
pp. 019459982095483
Author(s):  
Philip D. Knollman ◽  
Christine H. Heubi ◽  
Susan Wiley ◽  
David F. Smith ◽  
Sally R. Shott ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Down Syndrome ◽  
Clinical Characteristics ◽  
Medical Center ◽  
Demographic Data ◽  
Children With Down Syndrome ◽  
Medical Need ◽  
Obstructive Sleep ◽  
Significant Difference ◽  
History Of

Objectives To compare the demographic and clinical characteristics of children with Down syndrome who did and did not receive polysomnography to evaluate for obstructive sleep apnea after publication of the American Academy of Pediatrics’ guidelines recommending universal screening by age 4 years. Study Design Retrospective cohort study. Setting Single tertiary pediatric hospital. Methods Review was conducted of children with Down syndrome born between 2007 and 2012. Children who obtained polysomnography were compared with children who did not, regarding demographic data, socioeconomic status, and comorbidities. Results We included 460 children with Down syndrome; 273 (59.3%) received at least 1 polysomnogram, with a median age of 3.6 years (range, 0.1-8.9 years). There was no difference in the distribution of sex, insurance status, or socioeconomic status between children who received polysomnography and those who did not. There was a significant difference in race distribution ( P = .0004) and distance from home to the medical center ( P < .0001) between groups. Among multiple medical comorbidities, only children with a history of hypothyroidism ( P = .003) or pulmonary aspiration ( P = .01) were significantly more likely to have obtained polysomnography. Conclusions Overall, 60% of children with Down syndrome obtained a polysomnogram. There was no difference between groups by payer status or socioeconomic status. A significant difference in race distribution was noted. Proximity to the medical center and increased medical need appear to be associated with increased likelihood of obtaining a polysomnogram. This study illustrates the need for improvement initiatives to increase the proportion of patients receiving guideline-based screening.

Clinical Characteristics and Risk Factors for Developing Pulmonary Hypertension in Children with Down Syndrome

2018 ◽  
Vol 202 ◽  
pp. 212-219.e2 ◽  
Author(s):  
Douglas Bush ◽  
Csaba Galambos ◽  
D. Dunbar Ivy ◽  
Steven H. Abman ◽  
Kristine Wolter-Warmerdam ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pulmonary Hypertension ◽  
Down Syndrome ◽  
Clinical Characteristics ◽  
Children With Down Syndrome ◽  
Hypertension In Children

Clinical Characteristics of Dysphagia in Children with Down Syndrome

Dysphagia ◽  
2016 ◽  
Vol 31 (5) ◽  
pp. 663-671 ◽  
Author(s):  
Arwen Jackson ◽  
Jennifer Maybee ◽  
Maura K. Moran ◽  
Kristine Wolter-Warmerdam ◽  
Francis Hickey
Keyword(s):  
Down Syndrome ◽  
Clinical Characteristics ◽  
Children With Down Syndrome
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