Objectives: To assess the current situation of using hypertension drugs for outpatients at the examination department of Hau Nghia Regional General Hospital - Long An. Objects and methods: Study of Cross-sectional description, retrospection, non-intervention on 180 patients who came to examine and treat hypertension at the examination Department, stored on the software of the Hau Nghia Regional General Hospital - Long An. Results: Among the drug groups used to treat hypertension, the group of drugs used the most was calcium channel blockers (58.25%), the lowest was diuretics with 3.88%. The regimens used for patients, the number of regimens using one drug accounted for the largest proportion, accounting for 86.67%. The regimen using 2 drugs accounted for 12.22% and the lowest was the combination regimen of 3 drugs with only 2 patients, accounting for 1.11%. In monotherapy was preferred by the doctor over combination therapy, in which Amlodipine was the most prescribed drug. The number of times of drug use per day of some drugs did not comply with recommendations and drug interactions accounted for a high proportion. Conclusion: The treatment regimen of hypertension was mainly monotherapy with calcium blockers, the most common being Amlodipine. However, the number of drugs used per day of some drugs did not comply with recommendations and drug interactions accounted for a high proportion.
Drug interactions of non-dihydropyridine calcium channel blockers involving CYP3A enzymes and P-gp transporter protein
