scholarly journals Critical Interplay Between Neuropeptide Y and Sex Steroid Pathways in Bone and Adipose Tissue Homeostasis

2009 ◽  
Vol 24 (2) ◽  
pp. 294-304 ◽  
Author(s):  
Susan J Allison ◽  
Paul A Baldock ◽  
Ronaldo F Enriquez ◽  
EnJu Lin ◽  
Matthew During ◽  
...  

2011 ◽  
pp. P1-304-P1-304
Author(s):  
Maria Insenser ◽  
Rafael Montes ◽  
Jose L San-Millan ◽  
Hector F Escobar-Morreale


2018 ◽  
Vol 262 ◽  
pp. 12-19
Author(s):  
Guoqing Wang ◽  
Mark A. Cline ◽  
Elizabeth R. Gilbert


2019 ◽  
Vol 12 ◽  
pp. 20-25 ◽  
Author(s):  
Dongmei Wu ◽  
Yifu Qiu


Author(s):  
Jonathan R. Brestoff ◽  
Craig B. Wilen ◽  
John R. Moley ◽  
Yongjia Li ◽  
Wei Zou ◽  
...  


Bone Reports ◽  
2020 ◽  
Vol 13 ◽  
pp. 100686
Author(s):  
Giulia Frangi ◽  
Greet Kerckhofs ◽  
Jérémy Boulestreau ◽  
Florent Autrusseau ◽  
Joëlle Veziers ◽  
...  


2011 ◽  
Vol 54 ◽  
pp. S499
Author(s):  
R. Fucho ◽  
D. Balgoma ◽  
J. Balsinde ◽  
J.C. Fernandez-Checa ◽  
C. Garcia-Ruiz


Metabolism ◽  
1997 ◽  
Vol 46 (2) ◽  
pp. 179-185 ◽  
Author(s):  
Maria E. Ramirez ◽  
Martha P. McMurry ◽  
Gail A. Wiebke ◽  
Karon J. Felten ◽  
Kuishu Ren ◽  
...  


2014 ◽  
Vol 29 (4) ◽  
pp. 1414-1425 ◽  
Author(s):  
Edgardo Rodríguez‐Carballo ◽  
Beatriz Gámez ◽  
Andrés Méndez‐Lucas ◽  
Manuela Sánchez‐Freutrie ◽  
Antonio Zorzano ◽  
...  


2005 ◽  
Vol 288 (6) ◽  
pp. E1236-E1243 ◽  
Author(s):  
Elena Velkoska ◽  
Timothy J. Cole ◽  
Margaret J. Morris

Early life nutrition impacts on subsequent risk of obesity and hypertension. Several brain chemicals responsible for both feeding and cardiovascular regulation are altered in obesity. We examined effects of early postnatal overnutrition on blood pressure, brain neuropeptide Y (NPY), and adiposity markers. Rat pup litters were adjusted to either 3 or 12 male animals (overnutrition and control, respectively) on day 1 of life. After weaning, rats were given either a palatable high-fat diet or standard chow. Smaller litter pups were significantly heavier by 17 days of age. By 16 wk, the effect of litter size was masked by that of diet, postweaning. Small and normal litter animals fed a high-fat diet had similar increases in body weight, plasma insulin, leptin, and adiponectin concentrations, leptin mRNA, and fat masses relative to chow-fed animals. An increase in 11β-hydroxysteroid dehydrogenase-1 mRNA in white adipose tissue, and a decrease in uncoupling protein-1 mRNA in brown adipose tissue in both small litter groups at 16 wk of age, may represent a programming effect of the altered litter size. NPY concentration in the paraventricular nucleus of the hypothalamus was reduced in high fat-fed groups. Blood pressure was significantly elevated at 13 wk in high-fat-fed animals. This study demonstrates that overnourishment during early postnatal development leads to profound changes in body weight at weaning, which tended to abate with maturation. Thus the effects of long-term dietary intervention postweaning can override those of litter size-induced obesity.



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