High-sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers

2002 ◽  
Vol 27 (13) ◽  
pp. 1168 ◽  
Author(s):  
Eric O. Potma ◽  
David J. Jones ◽  
J.-X. Cheng ◽  
X. S. Xie ◽  
Jun Ye
Keyword(s):  
Raman Scattering ◽  
High Sensitivity ◽  
Picosecond Lasers ◽  
Anti Stokes

scholarly journals Delivery of picosecond lasers in multimode fibers for coherent anti-Stokes Raman scattering imaging

2010 ◽  
Vol 18 (12) ◽  
pp. 13017 ◽  
Author(s):  
Zhiyong Wang ◽  
Yaliang Yang ◽  
Pengfei Luo ◽  
Liang Gao ◽  
Kelvin K. Wong ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Multimode Fibers ◽  
Picosecond Lasers ◽  
Anti Stokes

High-sensitivity vibrational imaging with frequency modulation coherent anti-Stokes Raman scattering (FM CARS) microscopy

2006 ◽  
Vol 31 (12) ◽  
pp. 1872 ◽  
Author(s):  
Feruz Ganikhanov ◽  
Conor L. Evans ◽  
Brian G. Saar ◽  
X. Sunney Xie
Keyword(s):  
Raman Scattering ◽  
Frequency Modulation ◽  
High Sensitivity ◽  
Cars Microscopy ◽  
Anti Stokes

Synchronization of two passively mode-locked, picosecond lasers within 20 fs for coherent anti-Stokes Raman scattering microscopy

2002 ◽  
Vol 73 (8) ◽  
pp. 2843-2848 ◽  
Author(s):  
David J. Jones ◽  
Eric O. Potma ◽  
Ji-xin Cheng ◽  
Berndt Burfeindt ◽  
Yang Pang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Picosecond Lasers ◽  
Anti Stokes

scholarly journals Coherent Anti-Stokes Raman Scattering Microscopy and Its Applications

2020 ◽  
Vol 8 ◽  
Author(s):  
Shaowei Li ◽  
Yanping Li ◽  
Rongxing Yi ◽  
Liwei Liu ◽  
Junle Qu
Keyword(s):  
High Resolution ◽  
Raman Scattering ◽  
High Speed ◽  
High Sensitivity ◽  
Laser Source ◽  
Future Prospects ◽  
Non Invasive ◽  
Cars Microscopy ◽  
Anti Stokes

Coherent anti-Stokes Raman scattering (CARS) microscopy can provide high resolution, high speed, high sensitivity, and non-invasive imaging of specific biomolecules without labeling. In this review, we first introduce the principle of CARS microscopy, and then discuss its configuration, including that of the laser source and the multiplex CARS system. Finally, we introduce the applications of CARS in biomedicine and materials, and its future prospects.

scholarly journals High-resolution imaging of graphene by tip-enhanced coherent anti-Stokes Raman scattering

2019 ◽  
Vol 12 (01) ◽  
pp. 1841003 ◽  
Author(s):  
Xiaolong Kou ◽  
Qian Zhou ◽  
Dong Wang ◽  
Jinghe Yuan ◽  
Xiaohong Fang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Single Molecule ◽  
High Sensitivity ◽  
Single Atom ◽  
Raman Signal ◽  
Vibrational Coherence ◽  
Order Of Magnitude ◽  
Resolution Imaging ◽  
Molecular Signals ◽  
Anti Stokes

Coherent anti-Stokes Raman scattering (CARS) is able to enhance molecular signals by vibrational coherence compared to weak Raman signal. The surface or tip enhancement are successful technologies, which make it possible for Raman to detect single molecule with nanometer resolution. However, due to technical difficulties, tip-enhanced CARS (TECARS) is not as successful as expected. For single molecular detection, high sensitivity and resolution are two main challenges. Here, we reported the first single atom layer TECARS imaging on Graphene with the highest resolution about 20[Formula: see text]nm, which has ever been reported. The highest EF[Formula: see text] is about 104, the similar order of magnitude with SECARS (EF of tip is usually smaller than that of substrates). Such resolution and sensitivity is promising for medical, biology and chemical applications in the future.

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