scholarly journals Integration of Canonical and Noncanonical Wnt Signaling Pathways Patterns the Neuroectoderm Along the Anterior–Posterior Axis of Sea Urchin Embryos

PLoS Biology ◽  
2013 ◽  
Vol 11 (1) ◽  
pp. e1001467 ◽  
Author(s):  
Ryan C. Range ◽  
Robert C. Angerer ◽  
Lynne M. Angerer
Keyword(s):  
Wnt Signaling ◽  
Signaling Pathways ◽  
Sea Urchin ◽  
Sea Urchin Embryos ◽  
Anterior Posterior ◽  
Anterior Posterior Axis

ribbon encodes a novel BTB/POZ protein required for directed cell migration in Drosophila melanogaster

Development ◽  
2001 ◽  
Vol 128 (15) ◽  
pp. 3001-3015 ◽  
Author(s):  
Pamela L. Bradley ◽  
Deborah J. Andrew
Keyword(s):  
Cell Migration ◽  
Wnt Signaling ◽  
Signaling Pathways ◽  
Egf Receptor ◽  
Tracheal System ◽  
Directed Cell Migration ◽  
Posterior Migration ◽  
And Function ◽  
Dorsal Epidermis ◽  
Anterior Posterior

During development, directed cell migration is crucial for achieving proper shape and function of organs. One well-studied example is the embryonic development of the larval tracheal system of Drosophila, in which at least four signaling pathways coordinate cell migration to form an elaborate branched network essential for oxygen delivery throughout the larva. FGF signaling is required for guided migration of all tracheal branches, whereas the DPP, EGF receptor, and Wingless/WNT signaling pathways each mediate the formation of specific subsets of branches. Here, we characterize ribbon, which encodes a BTB/POZ-containing protein required for specific tracheal branch migration. In ribbon mutant tracheae, the dorsal trunk fails to form, and ventral branches are stunted; however, directed migrations of the dorsal and visceral branches are largely unaffected. The dorsal trunk also fails to form when FGF or Wingless/WNT signaling is lost, and we show that ribbon functions downstream of, or parallel to, these pathways to promote anterior-posterior migration. Directed cell migration of the salivary gland and dorsal epidermis are also affected in ribbon mutants, suggesting that conserved mechanisms may be employed to orient cell migrations in multiple tissues during development.

scholarly journals Canonical Wnt Signaling and Its Antagonist Regulate Anterior-Posterior Axis Polarization by Guiding Cell Migration in Mouse Visceral Endoderm

2005 ◽  
Vol 9 (5) ◽  
pp. 639-650 ◽  
Author(s):  
Chiharu Kimura-Yoshida ◽  
Hiroshi Nakano ◽  
Daiji Okamura ◽  
Kazuki Nakao ◽  
Shigenobu Yonemura ◽  
...  
Keyword(s):  
Cell Migration ◽  
Wnt Signaling ◽  
Visceral Endoderm ◽  
Canonical Wnt Signaling ◽  
Canonical Wnt ◽  
Anterior Posterior ◽  
Anterior Posterior Axis

Mutual antagonism of SoxB1 and canonical Wnt signaling in sea urchin embryos

2007 ◽  
Vol 7 (2) ◽  
pp. 174-180 ◽  
Author(s):  
Lynne M. Angerer ◽  
Alan P. Kenny ◽  
Laurel A. Newman ◽  
Robert C. Angerer
Keyword(s):  
Wnt Signaling ◽  
Sea Urchin ◽  
Canonical Wnt Signaling ◽  
Sea Urchin Embryos ◽  
Mutual Antagonism ◽  
Canonical Wnt
Sign in / Sign up

Export Citation Format

Share Document