scholarly journals Unconventional function of an Achaete-Scute homolog as a terminal selector of nociceptive neuron identity

PLoS Biology ◽  
2018 ◽  
Vol 16 (4) ◽  
pp. e2004979 ◽  
Author(s):  
Neda Masoudi ◽  
Saeed Tavazoie ◽  
Lori Glenwinkel ◽  
Leesun Ryu ◽  
Kyuhyung Kim ◽  
...  
Keyword(s):  
Nociceptive Neuron

scholarly journals Нелинейная динамика паттернов импульсной активности ноцицептивных нейронов при коррекции повреждающего болевого воздействия

2019 ◽  
Vol 89 (3) ◽  
pp. 465
Author(s):  
О.Е. Дик
Keyword(s):  
Bifurcation Analysis ◽  
Active Ingredient ◽  
Activity Pattern ◽  
Neuron Model ◽  
Nociceptive Neuron ◽  
Firing Activity ◽  
Comenic Acid ◽  
Pain Stimulation ◽  
Activation Gating ◽  
Nonopioid Analgesic

AbstractA bifurcation analysis of a nociceptive neuron model was performed to study how the firing activity pattern changes when an antinociceptive response to damaging pain stimulation arises in rat dorsal ganglia. Ectopic train activity was found to arise in the model. Suppression of train activity was demonstrated to proceed solely through modification of the activation gating structure of the Na _ V 1.8 slow sodium channel in response to comenic acid, which exerts an analgesic effect and is an active ingredient of the new nonopioid analgesic Anoceptin.

The Role of Slow Sodium Channels in GABAergic and NOergic Modulation of Nociceptive Neuron Excitability

2021 ◽  
Vol 51 (6) ◽  
pp. 831-836
Author(s):  
V. B. Plakhova ◽  
V. A. Penniyaynen ◽  
S. G. Terekhin ◽  
S. A. Podzorova ◽  
A. D. Kalinina ◽  
...  
Keyword(s):  
Sodium Channels ◽  
Nociceptive Neuron ◽  
Neuron Excitability

scholarly journals Author Correction: PD-L1 inhibits acute and chronic pain by suppressing nociceptive neuron activity via PD-1

2019 ◽  
Vol 22 (3) ◽  
pp. 503-503 ◽  
Author(s):  
Gang Chen ◽  
Yong Ho Kim ◽  
Hui Li ◽  
Hao Luo ◽  
Da-Lu Liu ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Neuron Activity ◽  
Nociceptive Neuron

scholarly journals THE GABA-ERGIC SYSTEM DOES NOT CONTROL THE NOCICEPTIVE RESPONSES OF PRIMARY SENSORY NEURON

2019 ◽  
Vol 19 (1S) ◽  
pp. 44-45
Author(s):  
V A Penniyaynen ◽  
S A Podzorova ◽  
S G Terekhin ◽  
B V Krylov ◽  
V B Plakhova
Keyword(s):  
Sensory Neuron ◽  
Sensory Neurons ◽  
Nervous Tissue ◽  
Molecular Mechanisms ◽  
Primary Sensory Neuron ◽  
Nociceptive Neuron ◽  
Wide Range ◽  
Nociceptive Responses ◽  
Activation Gating

The aim of the study was to elucidate the molecular mechanisms of the interconnection of the GABA-ergic and nociceptive systems at the level of the peripheral division of the CNS. The data obtained indicate that GABA does not affect the activation gating device of the NaV1.8 channel of the primary sensory neuron responsible for coding pain signals.This agent in a wide range of concentrations also does not affect the growth of neurites of sensory neurons of embryonic nervous tissue. These results confirm our assumption, expressed earlier that the asynaptic membrane of the primary nociceptive neuron is not under the control of the GABA-ergic system.

scholarly journals A18 DIETARY ANTIGEN RE-CHALLENGE INCREASES NOCICEPTIVE NEURON EXCITABILITY IN A POST-INFECTIOUS IBS MODEL.

2018 ◽  
Vol 1 (suppl_2) ◽  
pp. 29-30
Author(s):  
C D Lopez Lopez ◽  
J O Jaramillo Polanco ◽  
J Aguilera Lizarraga ◽  
S Vanner ◽  
D E Reed ◽  
...  
Keyword(s):  
Nociceptive Neuron ◽  
Neuron Excitability ◽  
Dietary Antigen ◽  
Post Infectious

scholarly journals Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron

2008 ◽  
Vol 105 (49) ◽  
pp. 19038-19043 ◽  
Author(s):  
M. I. Funez ◽  
L. F. Ferrari ◽  
D. B. Duarte ◽  
D. Sachs ◽  
F. Q. Cunha ◽  
...  
Keyword(s):  
Nociceptive Neuron ◽  
Pharmacodynamic Property
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