scholarly journals Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy

PLoS Biology ◽  
2020 ◽  
Vol 18 (3) ◽  
pp. e3000618 ◽  
Author(s):  
Linxiang Yin ◽  
Geoffrey Masuyer ◽  
Sicai Zhang ◽  
Jie Zhang ◽  
Shin-Ichiro Miyashita ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Botulinum Neurotoxin ◽  
Membrane Binding ◽  
Botulinum Neurotoxin B ◽  
Binding Loop

scholarly journals Characterization of α-crystallin-plasma membrane binding.

2002 ◽  
Vol 277 (2) ◽  
pp. 1628
Author(s):  
Brian A. Cobb ◽  
J. Mark Petrash
Keyword(s):  
Plasma Membrane ◽  
Membrane Binding ◽  
Plasma Membrane Binding

In vitro potency determination of botulinum neurotoxin B based on its receptor-binding and proteolytic characteristics

2016 ◽  
Vol 34 ◽  
pp. 97-104 ◽  
Author(s):  
Emina Wild ◽  
Ursula Bonifas ◽  
Jolanta Klimek ◽  
Jan-Hendrik Trösemeier ◽  
Beate Krämer ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin B

Characterization of the Membrane Binding Mode of the C2 Domain of PKCε†

Biochemistry ◽  
2003 ◽  
Vol 42 (40) ◽  
pp. 11661-11668 ◽  
Author(s):  
Senena Corbalán-Garcia ◽  
Susana Sánchez-Carrillo ◽  
Josefa García-García ◽  
Juan C. Gómez-Fernández
Keyword(s):  
Membrane Binding ◽  
Binding Mode ◽  
C2 Domain

Isolation and Characterization of Membrane Binding Proteins

1976 ◽  
pp. 183-242 ◽  
Author(s):  
Dale L. Oxender ◽  
Steven C. Quay
Keyword(s):  
Binding Proteins ◽  
Membrane Binding ◽  
Isolation And Characterization

Structural basis of cell surface receptor recognition by botulinum neurotoxin B

Nature ◽  
2006 ◽  
Vol 444 (7122) ◽  
pp. 1096-1100 ◽  
Author(s):  
Qing Chai ◽  
Joseph W. Arndt ◽  
Min Dong ◽  
William H. Tepp ◽  
Eric A. Johnson ◽  
...  
Keyword(s):  
Cell Surface ◽  
Botulinum Neurotoxin ◽  
Cell Surface Receptor ◽  
Structural Basis ◽  
Receptor Recognition ◽  
Surface Receptor ◽  
Botulinum Neurotoxin B

Characterization of neurocalcin delta membrane binding by biophysical methods

2019 ◽  
Vol 174 ◽  
pp. 291-299 ◽  
Author(s):  
Emmanuelle Hoareau ◽  
Nicolas Belley ◽  
Kristina Klinker ◽  
Bernard Desbat ◽  
Élodie Boisselier
Keyword(s):  
Membrane Binding

scholarly journals Substrate Recognition of VAMP-2 by Botulinum Neurotoxin B and Tetanus Neurotoxin

2008 ◽  
Vol 283 (30) ◽  
pp. 21153-21159 ◽  
Author(s):  
Sheng Chen ◽  
Cherisse Hall ◽  
Joseph T. Barbieri
Keyword(s):  
Botulinum Neurotoxin ◽  
Substrate Recognition ◽  
Tetanus Neurotoxin ◽  
Botulinum Neurotoxin B

scholarly journals Synthetic substrate for application in both high and low throughput assays for botulinum neurotoxin B protease inhibitors

2009 ◽  
Vol 19 (20) ◽  
pp. 5848-5850 ◽  
Author(s):  
Nicholas T. Salzameda ◽  
Joseph T. Barbieri ◽  
Kim D. Janda
Keyword(s):  
Protease Inhibitors ◽  
Botulinum Neurotoxin ◽  
Synthetic Substrate ◽  
Botulinum Neurotoxin B

scholarly journals Binding activity and immunogenic characterization of recombinant C-terminal quarter and half of the heavy chain of botulinum neurotoxin serotype A

2011 ◽  
Vol 7 (10) ◽  
pp. 1090-1095 ◽  
Author(s):  
Yun-Zhou Yu ◽  
Yao Ma ◽  
Yan-Xia Chen ◽  
Zheng-Wei Gong ◽  
Shuang Wang ◽  
...  
Keyword(s):  
Heavy Chain ◽  
Botulinum Neurotoxin ◽  
Binding Activity ◽  
Serotype A ◽  
Botulinum Neurotoxin Serotype A

Recombinant C fragment of botulinum neurotoxin B serotype (rBoNTB (HC)) immune response and protection in the rhesus monkey

Toxicon ◽  
2006 ◽  
Vol 47 (8) ◽  
pp. 877-884 ◽  
Author(s):  
James Boles ◽  
Michael West ◽  
Vicki Montgomery ◽  
Ralph Tammariello ◽  
M. Louise M. Pitt ◽  
...  
Keyword(s):  
Immune Response ◽  
Rhesus Monkey ◽  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin B
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