scholarly journals PTRF/Cavin-1 and MIF Proteins Are Identified as Non-Small Cell Lung Cancer Biomarkers by Label-Free Proteomics

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e33752 ◽  
Author(s):  
Angelo Gámez-Pozo ◽  
Iker Sánchez-Navarro ◽  
Enrique Calvo ◽  
María Teresa Agulló-Ortuño ◽  
Rocío López-Vacas ◽  
...  
Epigenomics ◽  
2020 ◽  
Vol 12 (19) ◽  
pp. 1751-1763
Author(s):  
Sachin Kumar ◽  
Monu Pandey ◽  
Surender K Sharawat

We aim to discuss comprehensively the role of long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs) in small-cell lung cancer (SCLC) biology and their clinical utility as cancer biomarkers. We searched the scientific literature to select articles related to the role of lncRNAs and circRNAs in SCLC biology or as cancer biomarkers. We identified that a number of lncRNAs and circRNAs can regulate key biological processes involved in SCLC development, including cell proliferation, metastasis and chemoresistance mainly acting as miRNA sponges. Also, the expression of a few lncRNAs and circRNAs predicted survival outcome depicting their utility as prognostic biomarkers. Further investigations on the role of lncRNAs and circRNAs in SCLC tumors may yield novel therapeutic targets for SCLC.


2011 ◽  
Vol 29 (15_suppl) ◽  
pp. 10561-10561
Author(s):  
L. Takacs ◽  
M. Guergova-Kuras ◽  
I. Kurucz ◽  
N. Tardieu ◽  
J. Kadas ◽  
...  

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