scholarly journals Y-Chromosome Analysis in Retuertas Horses

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e64985 ◽  
Author(s):  
Claudia Brandariz-Fontes ◽  
Jennifer A. Leonard ◽  
José Luis Vega-Pla ◽  
Niclas Backström ◽  
Gabriella Lindgren ◽  
...  
Author(s):  
Eriko Ochiai ◽  
Motoki Osawa ◽  
Shiori Satoh ◽  
Tomonori Tamura ◽  
Masato Nakatome ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rossana Santiago de Sousa Azulay ◽  
Luís Cristóvão Porto ◽  
Dayse Aparecida Silva ◽  
Maria da Glória Tavares ◽  
Roberta Maria Duailibe Ferreira Reis ◽  
...  

AbstractThis study aimed to investigate the relationship between genetic ancestry inferred from autosomal and Y chromosome markers and HLA genotypes in patients with Type 1 Diabetes from an admixed Brazilian population. Inference of autosomal ancestry; HLA-DRB1, -DQA1 and -DQB1 typifications; and Y chromosome analysis were performed. European autosomal ancestry was about 50%, followed by approximately 25% of African and Native American. The European Y chromosome was predominant. The HLA-DRB1*03 and DRB1*04 alleles presented risk association with T1D. When the Y chromosome was European, DRB1*03 and DRB1*04 homozygote and DRB1*03/DRB1*04 heterozygote genotypes were the most frequent. The results suggest that individuals from Maranhão have a European origin as their major component; and are patrilineal with greater frequency from the R1b haplogroup. The predominance of the HLA-DRB1*03 and DRB1*04 alleles conferring greater risk in our population and being more frequently related to the ancestry of the European Y chromosome suggests that in our population, the risk of T1D can be transmitted by European ancestors of our process miscegenation. However, the Y sample sizes of Africans and Native Americans were small, and further research should be conducted with large mixed sample sizes to clarify this possible association.


2004 ◽  
Vol 1 (4) ◽  
pp. 273-280 ◽  
Author(s):  
Robert A Scott ◽  
Colin Moran ◽  
Richard H Wilson ◽  
Will H Goodwin ◽  
Yannis P Pitsiladis

AbstractEast African athletes now dominate international distance running events from the 800 m to the marathon. Explanations for their phenomenal success have included optimal environmental conditions for developing distance running performance, psychological advantage and advantageous physiological characteristics. It is well established that genetics plays a role in determining inter-individual differences in exercise performance and adaptation to training stimuli. It is not known, however, to what extent inter-population differences (i.e. between ‘races’ and/or ethnic groups) in exercise performance can be attributed to genetics. There have been considerations that ‘black’ athletes are genetically adapted towards performance, given the concurrent success of athletes of West African ancestry in sprint events. However, the current notion of ‘race’ is not universally accepted, and genetic differences within and between populations are not clearly delineated by geographical or ethnic categorizations. Recent findings from mitochondrial DNA show that the populations from which Ethiopian athletes are drawn have not been isolated populations and are not genetically distinct from other Ethiopians. Y-chromosome analysis of the same population shows concurrent results, although some differences are present between athletes and the general Ethiopian population, suggesting an influence of the Y chromosome on athlete status in Ethiopia. It is concluded that there may be a role for genetics in the success of East African athletes; however, any genetic component to their success is unlikely to be limited to East Africans and is more likely to be found in other populations. At present it is unjustified to implicate a role for genetics in the success of East African runners when no genes have been identified as being important to their performance.


Nature ◽  
2001 ◽  
Vol 413 (6851) ◽  
pp. 6-6 ◽  
Author(s):  
Quirin Schiermeier

2005 ◽  
Vol 117 (5) ◽  
pp. 428-443 ◽  
Author(s):  
Manfred Kayser ◽  
Oscar Lao ◽  
Katja Anslinger ◽  
Christa Augustin ◽  
Grazyna Bargel ◽  
...  

2008 ◽  
Vol 72 (4) ◽  
pp. 519-534 ◽  
Author(s):  
B. Csányi ◽  
E. Bogácsi-Szabó ◽  
Gy. Tömöry ◽  
Á. Czibula ◽  
K. Priskin ◽  
...  

1999 ◽  
pp. 62-65 ◽  
Author(s):  
T Hayashi ◽  
Y Kageyama ◽  
K Ishizaka ◽  
T Tsujii ◽  
H Oshima

A 4-year-old boy with an undescending left testis, penoscrotal hypospadia and bilateral microphthalmia was admitted to our hospital. Chromosome analysis revealed a karyotype of 46, XX del(x)(p2 2,31) and the sex-determining region of the Y chromosome (SRY) was negative. The right testis was located in the scrotum and a left cystic ovary-like gonad, a salpinx and a unicorn uterus were found in the left inguinal canal. Histologically the gonad was an ovotestis in which primordial follicles covered infantile seminiferous tubules. Microphthalmia is observed in some congenital syndromes caused by interstitial deletion of the X chromosome. This case suggested that the short arm of the X chromosome was involved in the differentiation of the gonad. Very closely located follicles and infantile seminiferous tubules indicated that induction of meiosis in the fetus was controlled by the local microenvironment in follicles and seminiferous tubules, and not by the systemic hormonal condition.


2012 ◽  
Vol 109 (22) ◽  
pp. 8471-8476 ◽  
Author(s):  
M. C. Dulik ◽  
A. C. Owings ◽  
J. B. Gaieski ◽  
M. G. Vilar ◽  
A. Andre ◽  
...  

Development ◽  
1990 ◽  
Vol 109 (3) ◽  
pp. 635-646 ◽  
Author(s):  
R. Lovell-Badge ◽  
E. Robertson

Chimeric mice constructed with XY embryonic stem (ES) cells that had been multiply infected with a retroviral vector were used in a genetic screen to look for mutations affecting the sex determination pathway in mice. From a small number of chimeras screened one was identified that gave rise to a low proportion of XY females amongst his offspring. Analysis of the segregating patterns of retroviral insertions demonstrated that the mutation was found in a subset of the offspring derived from one originally infected ES cell. However, the mutation appeared to have occurred subsequent to the infection. Some of the XY females proved to be fertile, and the mutant phenotype was found to segregate exclusively with the Y chromosome. Analysis of the offspring also confirmed the absence of any retroviral insertion that could be correlated with the mutation. Further characterisation of the Y chromosome carrying the mutation by karyotypic analysis, and by Southern blotting with a range of Y-specific DNA probes suggested that there has been no gross deletion or rearrangement of the Y carrying the mutation. There also appeared to be no loss of Y-specific gene functions apart from that of testis determination. Moreover, the mutation is complemented by Sxr', the minimum portion of the mouse Y known to carry Tdy. From the phenotype and deduced location of the mutation, we conclude that it is within the Tdy locus. This is the first such mutation to be described in mice.


2020 ◽  
pp. 104376
Author(s):  
Claudia E. Yalta-Macedo ◽  
Eudosio A. Veli ◽  
Gerardo R. Díaz ◽  
Adriana Vallejo-Trujillo

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