AbstractMacrophages are unique cells of the innate immunity and can be found in various tissues (tissue resident macrophages; TRMs). Macrophages and TRMs play a pivotal role in tissue homeostasis and can contribute to the onset and progression of certain diseases. We and others have developed macrophage-based cellular immunotherapies and explored the field of immune cell farming using induced pluripotent stem cells (iPSCs). Combination of iPSCs and bioreactors opens new ways in cellular therapies.
MHC-Matched Induced Pluripotent Stem Cells Can Attenuate Cellular and Humoral Immune Responses but Are Still Susceptible to Innate Immunity in Pigs
