Weekly and Holiday-Related Patterns of Panic Attacks in Panic Disorder: A Population-Based Study

BackgroundThe co-occurrence of panic disorder and major depression in the same individual is common. A question to be answered is whether the comorbid disorder is a distinct one or may resemble one or other disorder. In this paper we examine whether the comorbid disorder is a distinct condition.MethodWe examined the symptom profiles and rates of comorbidity of panic attacks and DIS/DSM–III major depressive disorder in a population-based sample from four sites of the National Institute of Mental Health (NIMH) Epidemiologic Catchment Area Program (n= 12 668).ResultsThe co-occurrence of panic attacks and major depression over the lifetime was 11 times higher than expected by chance (OR = 11.4, 95% CI 9.5 to 13.6). Subjects with both panic and depression had worse symptoms than those who had only one disorder. However, the pattern of symptoms was remarkably similar, after overall severity was taken into account. Depressive symptoms associated with more severe forms of depression (e.g. guilt, suicidal thoughts or attempts, and motor disturbance) were more frequent in the comorbid group.ConclusionsThese findings may indicate a worse severity when the two disorders occur in the same individual.

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Increased Risk of Acute Myocardial Infarction for Patients With Panic Disorder: A Nationwide Population-Based Study

Psychosomatic Medicine ◽

10.1097/psy.0b013e3181ad55e3 ◽

2009 ◽

Vol 71 (7) ◽

pp. 798-804 ◽

Cited By ~ 48

Author(s):

Yi-Hua Chen ◽

Shang-Ying Tsai ◽

Hsin-Chien Lee ◽

Herng-Ching Lin

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Panic Disorder ◽

Population Based ◽

Population Based Study ◽

Increased Risk

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Panic Attacks and Panic Disorder in a Population-Based Sample of Active Canadian Military Personnel

The Journal of Clinical Psychiatry ◽

10.4088/jcp.09m05587blu ◽

2011 ◽

Vol 72 (01) ◽

pp. 66-74 ◽

Cited By ~ 7

Author(s):

D. Jolene Kinley ◽

John R. Walker ◽

Corey S. Mackenzie ◽

Jitender Sareen

Keyword(s):

Panic Disorder ◽

Military Personnel ◽

Population Based ◽

Panic Attacks ◽

Canadian Military

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Patterns of psychiatric and physical comorbidities associated with panic disorder in a nationwide population-based study in Taiwan

Acta Psychiatrica Scandinavica ◽

10.1111/j.1600-0447.2010.01541.x ◽

2010 ◽

Vol 123 (1) ◽

pp. 55-61 ◽

Cited By ~ 19

Author(s):

Y.-H. Chen ◽

H.-C. Lin

Keyword(s):

Panic Disorder ◽

Population Based ◽

Population Based Study

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Lifetime co-morbidity of panic attacks and major depression in a population-based study: age of onset

Psychological Medicine ◽

10.1017/s0033291700035315 ◽

1996 ◽

Vol 26 (5) ◽

pp. 991-996 ◽

Cited By ~ 26

Author(s):

L. Andrade ◽

W. W. Eaton ◽

H. D. Chilcoat

Keyword(s):

Major Depression ◽

Catchment Area ◽

Panic Attack ◽

Explanatory Variable ◽

Age Of Onset ◽

Population Based ◽

Panic Attacks ◽

Population Based Study ◽

Co Morbidity ◽

Time Dependent Covariates

SynopsisWe used survival analysis to test for a suspected effect of co-morbidity of DIS/DSM-III major depression and panic attack on the age of onset of each of these disorders, in a population-based sample from four sites of the National Institute of Mental Health (NIMH) Epidemiologic Catchment Area Program (N= 12668). The possible effects of gender and presence of a co-morbid disorder on age of onset of the single disorders were analysed using the Cox proportion-hazard model, with gender as an explanatory variable and the co-morbid disorders as time-dependent covariates. The disorders begin earlier in life when they are co-morbid than when they occur singly. The occurrence of one disorder increases the chance of occurrence of the other. Females have from 1·7 to almost twice the risk for developing panic and/or depression compared with men, even if the co-morbid disorder precedes the index disorder or is lifetime co-morbid. These findings are compatible with a hypothesis of a higher severity in co-morbid cases when compared with a single disorder.

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