scholarly journals In silico Identification and Validation of a Linear and Naturally Immunogenic B-Cell Epitope of the Plasmodium vivax Malaria Vaccine Candidate Merozoite Surface Protein-9

PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0146951 ◽  
Author(s):  
Rodrigo Nunes Rodrigues-da-Silva ◽  
João Hermínio Martins da Silva ◽  
Balwan Singh ◽  
Jianlin Jiang ◽  
Esmeralda V. S. Meyer ◽  
...  
Keyword(s):  
B Cell ◽  
Malaria Vaccine ◽  
Vaccine Candidate ◽  
Cell Epitope ◽  
Surface Protein ◽  
Merozoite Surface Protein ◽  
B Cell Epitope ◽  
Plasmodium Vivax Malaria ◽  
Malaria Vaccine Candidate ◽  
In Silico Identification

scholarly journals Immunoglobulin G3 Antibodies Specific for the 19-Kilodalton Carboxyl-Terminal Fragment of Plasmodium yoelii Merozoite Surface Protein 1 Transfer Protection to Mice Deficient in Fc-γRI Receptors

2000 ◽  
Vol 68 (5) ◽  
pp. 3019-3022 ◽  
Author(s):  
Peter Vukovic ◽  
P. Mark Hogarth ◽  
Nadine Barnes ◽  
David C. Kaslow ◽  
Michael F. Good
Keyword(s):  
Malaria Vaccine ◽  
Vaccine Candidate ◽  
Surface Protein ◽  
Merozoite Surface Protein ◽  
Plasmodium Yoelii ◽  
Merozoite Surface Protein 1 ◽  
Specific Immunoglobulin ◽  
Malaria Vaccine Candidate ◽  
Main Action ◽  
Carboxyl Terminal

ABSTRACT Merozoite surface protein 1 (MSP-119) is a leading malaria vaccine candidate. Specific antibodies contribute to immunity; binding to macrophages is believed to represent the main action of malaria antibodies. We show that an MSP-119-specific immunoglobulin G3 (IgG3) monoclonal antibody can passively transfer protection to mice deficient in the α chain of Fc-γRI whose macrophages cannot bind IgG3.

scholarly journals Immunogenicity of synthetic peptide constructs based on PvMSP9E795-A808, a linear B-cell epitope of the P. vivax Merozoite Surface Protein-9

Vaccine ◽  
2019 ◽  
Vol 37 (2) ◽  
pp. 306-313 ◽  
Author(s):  
Rodrigo Nunes Rodrigues-da-Silva ◽  
Daniely Correa-Moreira ◽  
Isabela Ferreira Soares ◽  
Paula Melo de-Luca ◽  
Paulo Renato Rivas Totino ◽  
...  
Keyword(s):  
B Cell ◽  
Synthetic Peptide ◽  
Cell Epitope ◽  
Surface Protein ◽  
Merozoite Surface Protein ◽  
B Cell Epitope ◽  
Linear B
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