scholarly journals Anterior Displacement of Lamina Cribrosa during Valsalva Maneuver in Young Healthy Eyes

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0159663 ◽  
Author(s):  
Yong Woo Kim ◽  
Michael J. A. Girard ◽  
Jean Martial Mari ◽  
Jin Wook Jeoung
2017 ◽  
Vol 26 (10) ◽  
pp. 866-874 ◽  
Author(s):  
Young Kook Kim ◽  
Ahnul Ha ◽  
Yong Ju Song ◽  
Kyeong Ik Na ◽  
Won June Lee ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yong Woo Kim ◽  
Dong Hyun Lee ◽  
Hyung Bin Lim ◽  
Baek-Lok Oh ◽  
Young Kook Kim ◽  
...  

2019 ◽  
Vol 104 (3) ◽  
pp. 398-403
Author(s):  
Ji-Ah Kim ◽  
Tae-Woo Kim ◽  
Eun Ji Lee ◽  
Michael J A Girard ◽  
Jean Martial Mari

Background/AimsTo investigate the relationship between the lamina cribrosa (LC) curvature and the microvasculature within the LC in treatment-naïve eyes with normal-tension glaucoma (NTG) and in healthy eyes.MethodsForty-one eyes with treatment-naïve NTG and 41 age and sex-matched healthy control eyes were included. The optic nerve head (ONH) area was scanned using spectral-domain optical coherence tomography (OCT) to examine the LC curvature quantified as the LC curvature index (LCCI). OCT angiography of the ONH area was performed to determine the LC vessel density (LCVD) in the en face images obtained from the layer segmented at the level of the LC. The LCVD was calculated as the percentage area occupied by vessels within the measured region.ResultsThe LCCI was larger (9.53±1.33 vs 6.55±1.02, p<0.001) and LCVD was smaller (28.0%±6.1% vs 35.2±6.3%, p<0.001) in NTG eyes than in healthy eyes. There were overall significant associations of a smaller retinal nerve fibre layer (RNFL) thickness (p<0.001), a smaller visual field mean deviation (MD) (p=0.003) and a larger LCCI (p≤0.004) with a smaller LCVD. In NTG group, the LCVD was positively associated with the RNFL thickness (p=0.012) and visual field MD (p=0.023), and negatively associated with the axial length (p≤0.013) and LCCI (p≤0.007). In healthy group, a smaller RNFL thickness (p=0.023) was associated with a smaller LCVD.ConclusionA larger LCCI was significantly associated with a smaller LCVD in treatment-naïve NTG eyes but not in healthy eyes, indicating that mechanical strain potentially influences the perfusion within the LC in eyes with NTG.


2014 ◽  
Vol 55 (3) ◽  
pp. 1241 ◽  
Author(s):  
Je Hyun Seo ◽  
Tae-Woo Kim ◽  
Robert N. Weinreb
Keyword(s):  

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