scholarly journals Prevalence of MRSA nasal carriage among pregnant women in Copenhagen

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0246343
Author(s):  
Mona Katrine Alberthe Holm ◽  
Thilde Nordmann Winther ◽  
Sisse Kammann ◽  
Marianne Skovby Rasmusson ◽  
Lis Brooks ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Pregnant Women ◽  
Intensive Care Units ◽  
Neonatal Intensive Care ◽  
Nasal Carriage ◽  
Neonatal Intensive Care Units ◽  
Methicillin Resistant ◽  
Low Prevalence

Background Methicillin resistant Staphylococcus aureus (MRSA) frequently causes outbreaks in neonatal intensive care units (NICUs). It is believed that MRSA predominantly enters the NICU with MRSA colonized parents. In Denmark, 27 MRSA NICU outbreaks have been registered between 2008 and 2019. Aim The aim of this study was to determine the prevalence of MRSA nasal carriage in pregnant women in Copenhagen and to clarify if MRSA screening during pregnancy could add to the prevention of NICU outbreaks. Methods All pregnant women 18 years or older were offered MRSA nasal screening at their first midwife visit between 13 and 20 weeks of gestation. Results 1778 pregnant women were included, two (0.11%) carried MRSA in the nose. Conclusion Infants of the two MRSA positive women were not admitted to a NICU and therefore the screening had no impact on NICU outbreaks. The low prevalence of MRSA found in this study does not justify MRSA screening of all pregnant women in Denmark.

scholarly journals Frequency of icaA and icaD determinants and biofilm formation among coagulase-negative staphylococci associated with nasal carriage in neonatal intensive care units

GERMS ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 61-70 ◽  
Author(s):  
Doaa Mabrouk Ahmed ◽  
Mona Abdel Wahab Abel Messih ◽  
Nermin Hassan Ibrahim ◽  
Mohamed Hussein Meabed ◽  
Soha Mahmoud Abdel-Salam
Keyword(s):  
Intensive Care ◽  
Intensive Care Units ◽  
Biofilm Formation ◽  
Neonatal Intensive Care ◽  
Nasal Carriage ◽  
Neonatal Intensive Care Units ◽  
Coagulase Negative Staphylococci

scholarly journals Sources and reservoirs of Staphylococcus capitis NRCS-A inside a NICU

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Marine Butin ◽  
Yann Dumont ◽  
Alice Monteix ◽  
Aurane Raphard ◽  
Christine Roques ◽  
...  
Keyword(s):  
Intensive Care ◽  
Pregnant Women ◽  
Intensive Care Units ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Resistant Clone ◽  
Single Institution ◽  
Staphylococcus Capitis ◽  
Potential Source ◽  
Disinfection Procedure

Abstract Background The methicillin-resistant clone Staphylococcus capitis NRCS-A, involved in sepsis in neonatal intensive care units (NICUs) worldwide, is able to persist and spread in NICUs, suggesting the presence of reservoirs inside each setting. The purpose of the present study was to identify these reservoirs and to investigate the cycle of transmission of NRCS-A in one NICU. Methods In a single institution study, NRCS-A was sought in 106 consecutive vaginal samples of pregnant women to identify a potential source of NRCS-A importation into the NICU. Additionally NICU caregivers and environmental including incubators were tested to identify putative secondary reservoirs. Finally, the efficacy of disinfection procedure in the elimination of NRCS-A from incubators was evaluated. Results No S. capitis was isolated from vaginal samples of pregnant women. Three of the 21 tested caregivers (14%) carried S. capitis on their hands, but none remain positive after a five-day wash-out period outside NICU. Moreover, the clone NRCS-A persisted during six consecutive weeks in the NICU environment, but none of the sampled sites was constantly contaminated. Finally in our before/after disinfection study, all of 16 incubators were colonized before disinfection and 10 (62%) incubators remained colonized with NRCS-A after the disinfection procedure. Conclusions The partial ineffectiveness of incubators’ disinfection procedures is responsible for persistence of NRCS-A inside a NICU, and the passive hand contamination of caregivers could be involved in the inter-patient transmission of S. capitis.

Surveillance swabbing for MRSA on neonatal intensive care units – is weekly nasal swabbing the best option?

2012 ◽  
Vol 13 (4) ◽  
pp. 120-124 ◽  
Author(s):  
Donovan Duffy ◽  
Mehdi Garbash ◽  
Mike Sharland ◽  
Nigel Kennea
Keyword(s):  
Staphylococcus Aureus ◽  
Intensive Care ◽  
Birth Weight ◽  
Intensive Care Units ◽  
Gestational Age ◽  
Optimal Strategy ◽  
Neonatal Intensive Care ◽  
Neonatal Intensive Care Units ◽  
Nasal Swabs ◽  
Surveillance Specimens

Most paediatric meticillin resistant Staphylococcus aureus (MRSA) infections occur in neonatal units, but evidence for ongoing MRSA surveillance is lacking and practice varies. The aim of this study was to determine the optimal strategy for neonatal MRSA screening according to swab site, gestational age and birth weight. MRSA detection on simultaneous weekly nasal and groin surveillance swabs and suspected infected sites was determined for all admissions to a tertiary neonatal unit over eight years. Twenty one thousand, seven hundred and thirty six surveillance specimens were examined (3,784 admissions). Infants colonised with MRSA were smaller and of lower gestational age compared with uncolonised infants ( p<0.0001). Infants initially positive on groin swabs alone (13/68; 19%) were of significantly greater gestational age and weight at birth compared with infants initially positive on nose swabs/both nose and groin swabs (55/68; 80%). Infants initially identified on groin swabs were all subsequently detected on nasal swabs or discharged within two weeks of age. 18/86 (21%) of MRSA cases were initially detected on swabbing suspected infected sites. Surveillance swabbing identified 43% of infants before MRSA bacteraemia. Eighty five per cent of colonised infants would be detected by weekly nasal swabs and by swabbing suspected infected sites. Groin swabs detect a small number of bigger mature babies who are discharged before two weeks of age.

Sign in / Sign up

Export Citation Format

Share Document