scholarly journals The effect of counseling, antiretroviral therapy and relationship on disclosing HIV positive status to sexual partner among adult HIV patients in Ethiopia: A systematic review and meta-analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0249887
Author(s):  
Melaku Yalew ◽  
Bezawit Adane ◽  
Bereket Kefale ◽  
Yitayish Damtie ◽  
Sisay Eshete Tadesse ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Hiv Testing ◽  
Sexual Partner ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Hiv Patients ◽  
Link Type ◽  
The Government

Background Human Immunodeficiency Virus (HIV) is continued as a major public health problem, especially in developing countries. Therefore, this study aimed to estimate the effect of counseling, antiretroviral therapy (ART) and relationship on disclosing HIV positive status to sexual partner among adult HIV patients in Ethiopia. Methods The Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) was used during this review. The study included both published and unpublished studies which were conducted in Ethiopia until the end of 2019. Different electronic databases (PubMed, Cochrane library, CINAHL, Global Health, HINARI and Google scholar) were searched. Data were extracted in Microsoft Excel sheet and STATA/SE 14 was used to meta-analysis. I2 and Egger test statistics were used to test heterogeneity and publication bias respectively. Results Twenty-two articles with 8,873 adult HIV infected peoples were included in this systematic review and meta-analysis. The pooled magnitude of disclosing HIV status to sexual partner was 74.63% [95% CI: (67.79, 81.47)]. Counseled [AOR = 4.96, 95% CI: (2.87, 8.55)], ART initiated [AOR = 4.78, 95% CI: (3.84, 5.94)] and who had a smooth relationship before HIV testing [AOR = 6.82, 95% CI: (3.49, 13.33)] were significantly associated with disclosing HIV status to sexual partner. Conclusions Disclosing HIV positive status to sexual partner in Ethiopia was low as the government invested in partner notification. Counseling, ART initiation and smooth relationship before HIV testing were significantly associated with disclosing HIV status to sexual partner. The government needs to strengthen pre and post HIV test counseling even after treatment started to increase disclosing status. Registration The protocol of this systematic review and meta-analysis was registered in the PROSPERO with a specific registration number: CRD42020161276; https://clinicaltrials.gov/.

scholarly journals Sero-positive HIV result disclosure to sexual partner in Ethiopia: a systematic review and meta-analysis

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Fantahun Ayenew Mekonnen ◽  
Ayenew Molla Lakew ◽  
Kindie Fentahun Muchie ◽  
Destaw Fetene Teshome
Keyword(s):  
Systematic Review ◽  
Positive Result ◽  
Sexual Partner ◽  
Meta Analysis ◽  
Outcome Variable ◽  
Hiv Positive ◽  
Hiv Status ◽  
Previous Discussion ◽  
Hiv Status Disclosure ◽  
Status Disclosure

Abstract Background The infection of HIV continues to be an important public health problem in Ethiopia. Disclosing own HIV positive result is crucial, and considered as a good indicator of behavior change towards HIV/AIDs. A systematic review and meta-analysis was conducted to pool the prevalence of positive HIV status disclosure to sexual partners and determine the influence of selected factors. Methods This systematic review and meta-analysis was conducted in Ethiopia among HIV positive people receiving health care at health facilities. In this review, primary studies were searched in Medline via PubMed, Google scholar and Google up to November, 2018. Data on disclosure of HIV positive result, knowledge of partner’s HIV status and prior discussion on HIV were extracted, and effect sizes like proportion and odds ratios were pooled. Heterogeneity and publication bias were assessed by chi-square and I2, and Egger test, respectively. Results A total of 12 studies with 4528 participants were included in to this review to estimate the prevalence of disclosure of HIV positive result to sexual partner, and 10 and 7 studies were included to determine the associations of the outcome variable with knowledge of sexual partner’s HIV status and with prior discussion on HIV, respectively. The pooled prevalence of HIV status disclosure to sexual partner was 73% (95% CI: 64, 82%). Having the knowledge of sexual partner’s HIV status [OR: 95%CI; 17.63 (7.88, 39.45)], and previous discussion on HIV [OR: 95% CI; 9.24 (5.56, 15.37)] increased the disclosure of own HIV positive result to sexual partner. The sub-group analysis indicated a prevalence of 74% in Oromia, 86% in Southern Nations Nationalities and Peoples (SNNPR), 87% in Amhara, 73% in Addis Ababa, and 54% in Tigray. Conclusions Disclosure of HIV status to sexual partner is lower than expected. Knowledge of partner’s HIV status and previous discussion on HIV were strong predictors of HIV positive status disclosure. Strategies helpful for encouraging open HIV discussion need to be strengthened to increase HIV positive result disclosure. Furthermore, since the heterogeneity of studies is high, large nationally representative study is suggested.

scholarly journals Contraceptive Use and Method Preferences among HIV Positive Women in Ethiopia: A Systematic Review and Meta-analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Getnet Gedefaw ◽  
Adam Wondmieneh ◽  
Asmamaw Demis
Keyword(s):  
Systematic Review ◽  
Unintended Pregnancy ◽  
Contraceptive Use ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Women Living With Hiv ◽  
Modern Contraceptives ◽  
Hiv Positive Women ◽  
Living With Hiv

Background. Preventing unintended pregnancies among HIV positive women has a vital role to prevent mother to child transmission. Besides, increasing access to contraceptives has a number of economical importance and reducing the costs for mitigating the unintended pregnancy consequences. Therefore, this study is aimed at assessing the contraceptive use and method of preference among HIV positive women in Ethiopia. Methods. A systematic review and meta-analysis reporting guideline was applied. Articles searched from the Scopus, Pubmed/MEDLINE, EMBASE, AJOL, Hinari, and Google scholar were included in this review. The Stata 11 software was used to compute the analysis. Heterogeneity of the studies was detected using the Cochran Q test and I2 test statistics. Egger’s test was used to check the evidence of publication bias within the studies. Subgroup analysis and sensitivity analysis was computed with the evidence of heterogeneity. Results. Ten thousand one hundred twenty one (10121) women living with HIV/AIDS were recruited in this study. The national estimated prevalence of contraceptive use among HIV positive women in Ethiopia was 57.78% (95% CI: 48.53-67.03). Injectables and male condom were the most preferred contraceptives accounted for 36.00% (95% CI: 6.64-45.35) and 32.74% (95% CI: 21.08-44.40), respectively. Discussion with husband/partner (AOR: 4.70, 95% CI: 2.18-10.12), disclosure of HIV status to spouse/partner (AOR: 2.18, 95% CI: 1.55-3.06), ever counseled for modern contraceptives (AOR: 2.79, 95% CI: 2.01-3.88), attending secondary and above education (AOR: 3.12, 95% CI: 2.15-4.51), and having more than one live child (AOR: 2.61, 95% CI: 1.86-3.66) were increasing the likelihood of contraceptive use whereas not currently married women (AOR: 0.23, 95% CI: 0.16-0.34) was decreases the odds of contraceptive use. Conclusion. In Ethiopia, more than half of the women living with HIV/AIDS were using contraceptives. Discussion with husband/partner, disclosure of HIV status to spouse/partner, ever counseled for modern contraceptives, attending secondary and above education, and having more than one live child were increasing the uptake of contraceptives among HIV positive women. Partner discussion, having adequate information towards contraceptive use, and having desired number of child could increase the utilization; as a result, obstetric complication with HIV positive women due to unintended pregnancy is significantly decreasing.

scholarly journals The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis

PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e112017 ◽  
Author(s):  
Anna Odone ◽  
Silvia Amadasi ◽  
Richard G. White ◽  
Theodore Cohen ◽  
Alison D. Grant ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Meta Analysis ◽  
Tuberculosis Treatment ◽  
Hiv Positive ◽  
The Impact

scholarly journals Kidney transplant outcomes in HIV-positive patients: a systematic review and meta-analysis

2019 ◽  
Vol 16 (1) ◽  
Author(s):  
Xin Zheng ◽  
Lian Gong ◽  
Wenrui Xue ◽  
Song Zeng ◽  
Yue Xu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Kidney Transplantation ◽  
Antiretroviral Therapy ◽  
Acute Rejection ◽  
Kidney Transplant ◽  
Graft Survival ◽  
Patient Survival ◽  
Meta Analysis ◽  
Infectious Complications ◽  
Hiv Positive

Abstract Background Kidney transplantation is now a viable alternative to dialysis in HIV-positive patients who achieve good immunovirological control with the currently available antiretroviral therapy regimens. This systematic review and meta-analysis investigate the published evidence of outcome and risk of kidney transplantation in HIV-positive patients following the PRISMA guidelines. Methods Searches of PubMed, the Cochrane Library and EMBASE identified 27 cohort studies and 1670 case series evaluating the survival of HIV-positive kidney transplant patients published between July 2003 and May 2018. The regimens for induction, maintenance therapy and highly active antiretroviral therapy, acute rejection, patient and graft survival, CD4 count and infectious complications were recorded. We evaluated the patient survival and graft survival at 1 and 3 years respectively, acute rejection rate and also other infectious complications by using a random-effects analysis. Results At 1 year, patient survival was 0.97 (95% CI 0.95; 0.98), graft survival was 0.91 (95% CI 0.88; 0.94), acute rejection was 0.33 (95% CI 0.28; 0.38), and infectious complications was 0.41 (95% CI 0.34; 0.50), and at 3 years, patient survival was 0.94 (95% CI 0.90; 0.97) and graft survival was 0.81 (95% CI 0.74; 0.87). Conclusions With careful selection and evaluation, kidney transplantation can be performed with good outcomes in HIV-positive patients.

Adherence to Antiretroviral Therapy Among HIV Patients in India: A Systematic Review and Meta-analysis

2020 ◽  
Vol 24 (7) ◽  
pp. 2130-2148 ◽  
Author(s):  
Apurba Chakraborty ◽  
Ronald C. Hershow ◽  
Dima M. Qato ◽  
Leslie Stayner ◽  
Mark S. Dworkin
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Meta Analysis ◽  
Hiv Patients

scholarly journals Risky Attitudes and Behaviors of HIV-Positive People After Diagnosis

2021 ◽  
Author(s):  
Sabri Atalay ◽  
Hazal Albayrak Ucak ◽  
Gursel Ersan ◽  
Ufuk Sönmez
Keyword(s):  
Sexual Behavior ◽  
Antiretroviral Therapy ◽  
Sexual Intercourse ◽  
Risky Sexual Behavior ◽  
Sexual Partner ◽  
Hiv Positive ◽  
Hiv Status ◽  
Unprotected Sexual Intercourse ◽  
Attitudes And Behaviors ◽  
And Behaviors

Objective: HIV/AIDS cases are increasing rapidly in our country. Although there are many transmission routes, unprotected sexual intercourse is the main reason for the increase in HIV prevalence. Despide newly data in the literature that show there is no HIV transmission from partners who have been given viral suppression by antiretroviral therapy, evaluation of sexual behavior pattern is still important for resource control. The aim of this study was to evaluate the changes in sexual behavior after diagnosis, the level of knowledge about safe sexuality, and the attitudes and behaviors of informing the sexual partner about HIV status in HIV-infected individuals under follow-up and treatment. Methods: A questionnaire consisting of fifteen questions was filled out by the volunteers who were followed up in the HIV outpatient clinic of our hospital and the data were evaluated with SPSS statistical package program. Results: The mean age of the fifty participants was 38 years. Most of them are men, 40% stated that they are gay and 40% of them are married. Seventy percent of the respondents stated that the frequency of risky sexual behavior decreased after being diagnosed with HIV. However, perhaps the most striking finding of our study is that approximately one third of the participants never informed their sexual partner about their HIV status and 44% said they did not use condoms during sexual intercourse. More than half of the participants stated that they would like to receive information about safe sex and sexually transmitted infections. They also stated that they wanted to get this information from physicians. Conclusion: As a result, there is a decrease in risky sexual behaviors after diagnosis in HIV positive patients. However, risky behaviors such as not using condoms still continue. Therefore, it is necessary to ensure that viral loads are negative with regular antiretroviral therapy and to promote safe sexual behavior.

scholarly journals Highly active antiretroviral therapy for critically ill HIV patients: A systematic review and meta-analysis

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0186968 ◽  
Author(s):  
Hugo Boechat Andrade ◽  
Cassia Righy Shinotsuka ◽  
Ivan Rocha Ferreira da Silva ◽  
Camila Sunaitis Donini ◽  
Ho Yeh Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antiretroviral Therapy ◽  
Critically Ill ◽  
Highly Active Antiretroviral Therapy ◽  
Meta Analysis ◽  
Hiv Patients ◽  
Highly Active

scholarly journals Dual contraceptive utilization and determinant factors among HIV positive women in Ethiopia: a systematic review and meta-analysis, 2020

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Alemu Degu Ayele ◽  
Bekalu Getnet Kassa ◽  
Fentahun Yenealem Beyene ◽  
Dagne Addisu Sewyew ◽  
Gedefaye Nibret Mihretie
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Hiv Positive Women ◽  
Pooled Prevalence ◽  
Post Test ◽  
Contraceptive Utilization ◽  
Open Discussion ◽  
Partner Involvement

Abstract Background Dual contraceptive is the use of a barrier like condom along with any modern contraceptive methods which has double significance for the prevention STI including HIV and unintended pregnancy. The prevalence and determinants of dual contraceptive utilization described by different studies were highly inconsistent in Ethiopia. Therefore, this systematic review and meta-analysis aimed to estimate the pooled prevalence and determinants of dual contraceptive utilization among HIV positive women in Ethiopia. Methods International database mainly Pub Med, Google scholar, HINARI, EMBASE, Cochrane Library, AJOL was applied to identify original studies. STATA software version 14 was applied to analyze the pooled prevalence of dual contraceptive. I2 test statistics was computed to check the presence of heterogeneity across the studies and eggers test was used to identify publication bias. The pooled prevalence of dual contraceptive utilization was estimated by using a random effects model. The associations between determinants and dual contraceptive utilization were evaluated by using both random and fixed effect models. Result A total 9 studies with 9168 HIV positive women were enrolled in this study. The pooled prevalence of dual contraceptive utilization among HIV positive women in Ethiopia was 26.14% (95% CI 21.20–31.08). Disclosure of HIV status (OR = 4.18,95%CI:2.26–7.72), partner involvement in post-test counselling (OR = 2.31,95%CI:1.63–3.25), open discussion about dual contraceptive with partner (OR = 4.27 95% CI:1.69–10.77), provision of counselling on dual contraceptives by health care provider (OR = 4.47,95% CI:3.81–5.24) and CD4 count > 350 cells/ mm3 (OR = 3.87,95%CI:3.53–4.23) were among the significant factors associated with dual contraceptive utilization. Conclusion The overall prevalence of dual contraceptive utilization among HIV positive women was significantly low. Disclosure of HIV status, partner involvement in post-test counselling, open discussion about dual contraceptive with partner, counselling on dual contraceptive by health care provider and CD4 count > 350 cells/ mm3 were positively affect dual contraceptive utilization. This study implies the need to develop plans and policies to improve partner involvement posttest counseling, integrate the counseling and provision of dual contraceptive at ART clinic at each level of health system.

Human Immunodeficiency Virus Positive status disclosure to a sexual partner and its determinant factors in Ethiopia. A systematic review and meta-analysis.

2020 ◽  
Author(s):  
Fikadu Ambaw Yehualashet ◽  
Eleni Tesfaye Tegegne ◽  
Mekbib Kassa Tessema ◽  
Mulualem Endeshaw
Keyword(s):  
Systematic Review ◽  
Human Immunodeficiency Virus ◽  
Meta Analysis ◽  
Hiv Positive ◽  
Hiv Status ◽  
Pooled Prevalence ◽  
Immunodeficiency Virus ◽  
Regression Test ◽  
Status Disclosure ◽  
Hiv Aids

Abstract Background: Disclosure of Human Immunodeficiency Virus positive status significantly reduced the transmission of HIV; yet, it remains a challenge for many HIV patients. Disclosure serves plays a crucial role to raise awareness and to reduce risky behaviors. Hence, this study aimed to determine the pooled prevalence and effect sizes of determinant factors of HIV positive status disclosure through a systematic review and meta-analysis of the results of the existing primary studies in Ethiopia. Method: This systematic review and meta-analysis was aimed to determine prevalence of HIV positive status disclosure and associated factors by considering and searching published primary articles from different sources. A sensitivity test was conducted to evaluate the presence of influential studies. Besides, the heterogeneity test has been conducted; and publication bias was examined through observing the funnel plot as well as objectively by interpreting the Egger’s regression test. Following the Egger’s regression test, P-value <0.05 was considered as statistically significant at 95% Confidence Interval. Result: A total of 18 primary studies were searched from different data sources. The overall pooled prevalence of HIV positive status disclosure among adult PLWHA in Ethiopia was indicated to be 75.95% (95% CI:69.93-81.98); the highest and lowest pooled estimated HIV status disclosure was in Amhara (82.78%) and Tigray (54.31%) regions respectively. Furthermore, Knowing the HIV positive status of sexual partner, AOR=19.66(95% CI: 10.19-37.91), having prior discussion about HIV testing with their partner, AOR=9.18(95% CI: 5.53-15.24), got Human Immunodeficiency Virus pretest counseling service AOR=4.29(95% CI: 2.56-7.21) and being a member of HIV/AIDS associations, AOR=3.34(95% CI: 2.17-5.12), were significantly associated with HIV positive status disclosure among People living With HIV/AIDS in Ethiopia.Conclusion: The pooled national estimate of HIV/AIDS positive status disclosure is low as compared to the WHO disclosure rate of developing countries and the findings of other national and international studies. Ministry of health and other stakeholders shall design new approaches and strategies to encourage disclosure of HIV status, educate the public about the negative impact of nondisclosure within family members. Health care providers working at Human HIV test centers shall emphasis extensive counseling on disclosure of status to a partner. Moreover, different stakeholders, health workers and community members shall establish, organize, and support HIV/AIDS Associations and motivate HIV positive people to be engaged and participated.

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