scholarly journals Bayesian structural equation modeling for post treatment health related quality of life among tuberculosis patients

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0252205
Author(s):  
Mahalingam Vasantha ◽  
Malaisamy Muniyandi ◽  
Chinnaiyan Ponnuraja ◽  
Ramalingam Srinivasan ◽  
Perumal Venkatesan

Background The use of Bayesian Structural Equation Model (BSEM) to evaluate the impact of TB on self-reported health related quality of life (HRQoL) of TB patients has been not studied. Objective To identify the factors that contribute to the HRQoL of TB patients using BSEM. Methods This is a latent variable modeling with Bayesian approach using secondary data. HRQoL data collected after one year from newly diagnosed 436 TB patients who were registered and successfully completed treatment at Government health facilities in Tiruvallur district, south India under the National TB Elimination Programme (NTEP) were used for this analysis. In this study, the four independent latent variables such as physical well–being (PW = PW1-7), mental well-being (MW = MW1-7), social well-being (SW = SW1-4) and habits were considered. The BSEM was constructed using Markov Chain Monte Carlo algorithm for identifying the factors that contribute to the HRQoL of TB patients who completed treatment. Results Bayesian estimates were obtained using 46,300 observations after convergence and the standardized structural regression estimate of PW, MW, SW on HRQoL were 0.377 (p<0.001), 0.543 (p<0.001) and 0.208 (p<0.001) respectively. The latent variables PW, MW and SW were significantly associated with HRQoL of TB patients. The age was found to be significantly negatively associated with HRQoL of TB patients. Conclusions The current study demonstrated the application of BSEM in evaluating HRQoL. This methodology may be used to study precise estimates of HRQoL of TB patients in different time points.

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Mina Moeineslam ◽  
Parisa Amiri ◽  
Mehrdad Karimi ◽  
Sara Jalali-Farahani ◽  
Niloofar Shiva ◽  
...  

Abstract Background Although several studies indicate the effects of diabetes type 2 on health-related quality of life (HRQoL) in female subjects, the related impact of the disease on HRQoL in their family members has rarely been the focus of the empirical research. In this study we aim to investigate associations between diabetes in women and the HRQoL in these women and their family members, using the structural equation modeling (SEM). Methods This family-based study was conducted on 794 women (11.1% with diabetes) as well as their spouses and children who participated in the Tehran Lipid and Glucose Study (TLGS) from 2014 to 2016. Data on HRQoL were collected using the Iranian version of the Short-Form 12-Item Health Survey version 2 (SF-12v2) and the Pediatric Quality of Life Inventory version™ 4.0 (PedsQL). SEM was conducted to evaluate the network of associations among studied variables. Data were analyzed using IBM SPSS Statistics & AMOS version 23 software. Results Mean age of women was 41.37 ± 5.32 years. Diabetes in women significantly affected their mental HRQoL (β = − 0.11, P < 0.01) but showed no significant direct associations with physical and mental HRQoL in their spouses or their children. However, poor mental HRQoL in women with diabetes was associated with decrease in both physical (β = − 0.02, P = 0.013) and mental (β = − 0.03, P < 0.01) HRQoL in their spouses and total HRQoL score in children (β = − 0.02, P < 0.01). Conclusions Among women with diabetes type 2, beyond its effect on their mental HRQoL per se, demonstrated a negative association with the self-assessment of health status in their spouses and children. Such familial consequences are mainly attributed to the negative effect of the disease on the mental rather than the physical HRQoL in women with diabetes.


2007 ◽  
Vol 16 (7) ◽  
pp. 1193-1202 ◽  
Author(s):  
Stacie M. Metz ◽  
Kathleen W. Wyrwich ◽  
Ajit N. Babu ◽  
Kurt Kroenke ◽  
William M. Tierney ◽  
...  

2012 ◽  
Vol 15 (1) ◽  
pp. 177-186 ◽  
Author(s):  
Tania Gaspar ◽  
José Pais Ribeiro ◽  
Margarida Gaspar de Matos ◽  
Isabel Leal ◽  
Aristides Ferreira

The main objective of this study was to build a model, which includes personal and social factors, that helps to highlight factors that promote health-related quality of Life (HRQoL) in children and in adolescents. A sample of 3195 children and adolescents was acquired from 5th and 7th graders from all five Portuguese regions. In this study three independent latent variables were specified – Physical, Psychological and Social and two dependent latent variables were measured: Health behavior and Quality of Life. The integrative model was composed by different components: (1) health-related quality of life, integrated by 8 dimensions from KIDSCREEN-52; (2) health behavior, (3) variables related to physical health; (4) variables related to social health; (5) variables related to psychological health. As results were found strong correlation between psychological dimensions and self-esteem and other factors and a structural equation model was developed. The model presented a RMSEA index of .08. Similarly, adjustment levels for the CFI, NFI and IFI vary above or around .90, which suggests a good adjustment for the hypothesized model. The model presented significant qui-square.This study showed that in all the samples studied, the psychological variables were those that contributed at a superior level to HRQoL.


2016 ◽  
Vol 57 (1) ◽  
pp. 58-65 ◽  
Author(s):  
Jafar Hassanzadeh ◽  
Mohsen Asadi-Lari ◽  
Abdolvahab Baghbanian ◽  
Haleh Ghaem ◽  
Aziz Kassani ◽  
...  

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