Oxytetracycline-hydrocortisone ointment reduces the occurrence of both dry socket and post-extraction pain after third molar extraction: An observational study

Objectives Dry socket and post-extraction pain are typical discomforts experienced by patients after tooth extraction. In this study, we inserted gauze coated with oxytetracycline-hydrocortisone ointment into the extraction socket immediately after lower third molar extraction and then evaluated the occurrence of dry socket and post-extraction pain compared with gauze non-insertion. Methods This retrospective study was carried out on patients undergoing lower third molar extraction in the Department of Oral Surgery at Shizuoka Prefectural General Hospital in Shizuoka, Japan from November 2018 to October 2019. A comparison was carried out between a gauze-insertion group and a non-insertion group. The occurrence versus non-occurrence of dry socket was determined, and degree of pain was assessed based on a visual analogue scale (VAS) and on patients reporting the number of loxoprofen sodium oral analgesic tablets (60mg/tablet) that they had taken. Dry socket was defined as patient-reported spontaneous pain that did not subside 1 to 3 days postoperatively. Spontaneous post-extraction pain was recorded four times: on the operative day, on the first postoperative day (POD1), on POD3, and during suture removal (POD7). Results The occurrence of dry socket was lower in the gauze-insertion group than in the non-insertion group (0.9%, 2/215 vs. 19.6%, 9/46, p<0.001). The results also showed that both VAS-defined pain level and the number of analgesic tablets taken were lower in the gauze-insertion group than in the non-insertion group on POD3 and POD7. Conclusions and clinical relevance Inserting gauze coated with oxytetracycline-hydrocortisone ointment into the extraction socket immediately after third molar extraction reduces the occurrence of both dry socket and post-extraction pain.

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Efficacy of sticky bone as a novel autologous graft for mandibular third molar extraction socket healing - An evaluative study

Annals of Maxillofacial Surgery ◽

10.4103/ams.ams_40_20 ◽

2020 ◽

Vol 10 (2) ◽

pp. 335

Author(s):

TaherAbbas Rupawala ◽

ShitalMayank Patel ◽

NaiyaHitesh Shah ◽

KunjBhupeshchandra Sanghvi ◽

SanjayVinubhai Makwana ◽

...

Keyword(s):

Third Molar ◽

Extraction Socket ◽

Autologous Graft ◽

Evaluative Study ◽

Third Molar Extraction ◽

Mandibular Third Molar ◽

Socket Healing ◽

Molar Extraction

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“Importance of Plasma Rich Growth Factors In Tooth Socket-In Concern of DRY SOCKET” (A Comperative Study)

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v7i09.016 ◽

2020 ◽

Vol 7 (09) ◽

pp. 5039-5043

Author(s):

Dr santosh Mishra ◽

Shukla M ◽

Arya V

Keyword(s):

Growth Factors ◽

Healing Rate ◽

Third Molar ◽

Wilcoxon Test ◽

Control Group ◽

Surgical Removal ◽

Dry Socket ◽

Third Molar Extraction ◽

Significant Difference ◽

Molar Extraction

Introduction: The high prevalence of dry socket or alveolar osteitis (AO) is of concern in surgical removal of third molars. The aim of the present study was to assess the preventive effect of plasma rich in growth factors (PRGF) on AO and also its effect on pain management and healing acceleration in third molar extraction sockets of high-risk patients. Materials and Methods: This split-mouth, double-blind clinical trial included 40 bilateral third molar extractions (80 sockets) with at least one identified risk factor for AO. PRGF was obtained from patient’s own blood, based on manufacturer’s instruction, and blindly placed in one of the two bilateral sockets (PRGF group; n = 20) of each patient. The contralateral socket was treated with a placebo (control group; n = 20). Samples were evaluated for AO and pain incidence on days 2, 3 and 4 and healing and infection on days 3 and 7. Data were analyzed in SPSS v16 using Wilcoxon test. Results: There was a significant difference in dry socket and pain incidence and healing rate between the two groups. Intensity of pain and occurrence of dry socket in the study group was lower than the controls. Also the healing rate was higher (P < 0.05) for the PRGF group. No sign of infection was seen in either group. Conclusion: The application of PRGF may significantly reduce the incidence of AO or its associated pain and may accelerate healing. The prophylactic use of PRGF following third molar extraction may be suggested especially in the patients at risk of AO.

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