Swept-source OCT reduces the risk of axial length measurement errors in eyes with cataract and epiretinal membranes

Aims To compare the biometric data from partial coherence interferometry (PCI) and swept-source OCT (SS-OCT) in patients with age-related cataract and epiretinal membrane (ERM): ERM, ERM with foveoschisis and macular pseudohole. Methods 49 eyes of 49 subjects including 36 ERM, 9 ERM foveoschisis and 4 macular pseudohole were analysed to evaluate the axial length (AL) measurements and the presence of AL measurement errors, defined basing on the shape of the biometric output graphs and on the concordance of AL values between instruments. Eyes with ERM were divided in four stages according to OCT features (i.e. presence/absence of the foveal pit, presence of ectopic inner foveal layers, disrupted retinal layers). Results The devices provided similar mean AL measurements in all subgroups, with differences <0.1 mm in 41/49 cases (83.6%). AL measurement errors were observed in ERM stages 3 and 4, characterized by ectopic inner foveal layers, and were significantly more frequent with the PCI (8/17, 47%) as compared with the SS-OCT device (2/17, 12%), p = 0.02. The refractive prediction error in cases with AL measurement errors was significantly greater using the PCI compared to the SS-OCT device (p<0.05). Conclusion Both devices provide reliable biometric data in the majority of patients and can be used in the preoperative assessment of patients with age-related cataract and ERM. In eyes with ectopic inner foveal layers, attention should be paid as AL measurement and refractive prediction errors may occur, more frequently with the PCI device.

Download Full-text

Analysis of Lens Thickness Distribution Based on Swept-Source Optical Coherence Tomography (SS-OCT)

Journal of Ophthalmology ◽

10.1155/2021/4717996 ◽

2021 ◽

Vol 2021 ◽

pp. 1-6

Author(s):

Xi Feng ◽

Yong Wang ◽

Jianheng Liang ◽

Yali Xu ◽

Julio Ortega-Usobiaga ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Negative Correlation ◽

Axial Length ◽

Central Corneal Thickness ◽

Corneal Thickness ◽

Anterior Chamber Depth ◽

Biometric Data ◽

Swept Source ◽

Age Related ◽

Cataract Patients

Objective. This study aimed to analyze the distribution of lens thickness (LT) and its associations in age-related cataract patients based on swept-source optical coherence tomography (SS-OCT). Methods. This cross-sectional study included 59,726 Chinese age-related cataract patients. Only right-eye data were included in the study. Repeated measures of ocular parameters were performed using an IOL Master 700 device. The distributions of ocular biometric data including anterior chamber depth (ACD), LT, axial length (AL), central corneal thickness (CCT), white-to-white (WTW), and mean keratometry (MK) and their associations with age were assessed. The anterior segment (AS) was measured as the sum of CCT, ACD, and LT, while the vitreous chamber depth (VCD) was calculated as the difference between AL and AS. The values of LT : AL, AS : AL, and VCD : AL in different AL groups and their changes are the main outcome measures used to observe the proportion of the anterior and posterior segments of the eye. Results. Biometric data were available for 59,726 individuals. The mean age was 68.81 years (range = 40–100); 40.62% were male and 59.38% were female. Mean anterior chamber depth (ACD) was 3.02 ± 0.44 mm, mean LT was 4.51 ± 0.44 mm, mean axial length (AL) was 23.89 ± 1.92 mm, mean central corneal thickness (CCT) was 0.53 ± 0.03 mm, mean white-to-white (WTW) was 11.64 ± 0.44 mm, and mean keratometry (MK) was 44.27 ± 1.65 diopter. Female patients had shorter AL, shallower ACD, smaller CCT and WTW, decreased LT, and steeper corneas ( p < 0.005). ACD revealed the strongest negative correlation ( p ≤ 0.001, r = –0.682) with LT. Age ( p ≤ 0.001, r = 0.348) showed a moderate positive correlation, whereas MK ( p ＜ 0.05, r = 0.011), CCT ( p ≤ 0.001, r = 0.041) had a weak positive correlation and WTW ( p ≤ 0.001, r = –0.034) had a weak negative correlation with LT. A nonlinear correlation was found between LT and AL. LT increased with age in both males and females. LT changed variably in eyes with AL less than 27 mm, LT decreased as AL increased, then LT gradually increased as AL increased in extremely long and extra-long eyes ( p ≤ 0.001). LT : AL and AS : AL decreased as AL increased, VCD : AL gradually increased as AL increased in highly myopic eyes, and VCD : AL increased by about 0.01 for every 1 mm increase in AL. Conclusions. Among Chinese age-related cataract patients, we found LT to have the strongest relation with ACD. The lens was thicker in elderly patients and women. The correlation between LT and AL is not a simple negative correlation; with the increase of age, LT decreases first and then increases. The proportion of VCD is constantly rising with the elongation of AL.

Download Full-text

Comprehensive Comparison of Axial Length Measurement With Three Swept-Source OCT-Based Biometers and Partial Coherence Interferometry

Journal of Refractive Surgery ◽

10.3928/1081597x-20190109-01 ◽

2019 ◽

Vol 35 (2) ◽

pp. 115-120 ◽

Cited By ~ 11

Author(s):

Jinhai Huang ◽

Hao Chen ◽

Yue Li ◽

Zhongxing Chen ◽

Rongrong Gao ◽

...

Keyword(s):

Axial Length ◽

Length Measurement ◽

Partial Coherence ◽

Swept Source ◽

Partial Coherence Interferometry ◽

Comprehensive Comparison ◽

Swept Source Oct

Download Full-text

En Face Swept Source OCT Study of Neovascular Age-Related Macular Degeneration

Atlas of Swept Source Optical Coherence Tomography ◽

10.1007/978-3-319-49840-9_6 ◽

2017 ◽

pp. 49-56

Author(s):

Ignacio Flores-Moreno ◽

Luis Arias-Barquet ◽

Jorge Ruiz-Medrano ◽

José M. Ruiz-Moreno ◽

Josep M. Caminal

Keyword(s):

Macular Degeneration ◽

Age Related Macular Degeneration ◽

Swept Source ◽

Age Related ◽

En Face ◽

Swept Source Oct

Download Full-text

Comparison of axial length using a new swept-source optical coherence tomography-based biometer - ARGOS with partial coherence interferometry- based biometer -IOLMaster among school children

PLoS ONE ◽

10.1371/journal.pone.0209356 ◽

2018 ◽

Vol 13 (12) ◽

pp. e0209356 ◽

Cited By ~ 1

Author(s):

Jameel Rizwana Hussaindeen ◽

Ephrame G. Mariam ◽

Sushil Arunachalam ◽

Ramakrishnan Bhavatharini ◽

Aparna Gopalakrishnan ◽

...

Keyword(s):

Optical Coherence Tomography ◽

School Children ◽

Axial Length ◽

Partial Coherence ◽

Optical Coherence ◽

Swept Source ◽

Partial Coherence Interferometry

Download Full-text

Comparative analysis of two optical biometry devices: high wavelength swept source OCT versus partial coherence interferometry

International Ophthalmology ◽

10.1007/s10792-021-02036-0 ◽

2021 ◽

Author(s):

Eszter Szalai ◽

Adrienne Csutak

Keyword(s):

Anterior Chamber Depth ◽

Partial Coherence ◽

Anterior Surface ◽

Swept Source ◽

Partial Coherence Interferometry ◽

Significant Difference ◽

Swept Source Oct ◽

Iol Power ◽

The Difference ◽

High Wavelength

Abstract Purpose To study the reproducibility of measurements performed with a recently developed multimodal high resolution swept source optical coherence tomography (SSOCT) and to make comparisons with a partial coherence interferometry (PCI) biometer. Methods One hundred and fifty-two eyes of 152 subjects were involved in this study with a mean age of 65.71 ± 13.86 years (26–85 years). Anterior surface keratometry (K), anterior chamber depth (ACD), white-to-white (WTW) and axial length (AL) values were recorded by the SSOCT (ANTERION, Heidelberg Engineering Ltd, Germany) and PCI (IOLMaster 500, version 5.5, Carl Zeiss Meditec, Germany). Intraocular lens (IOL) power was calculated based on ANTERION and IOLMaster keratometry values by using five traditional vergence formulas. Results Anterior surface simulated keratometry values did not differ significantly between the IOLMaster and ANTERION (P > 0.05). AL measurements were successful in 95% of the cases both with the SSOCT and PCI. No significant difference was disclosed between the two instruments (P = 0.229). For WTW measurements, a significant difference was observed between the two optical biometers (P < 0.0001). The difference between PCI and SSOCT in IOL powers was statistically significant for SRK/T, Hoffer and Holladay formulas (P < 0.001). Conclusion Our results implicated an overall good reproducibility of anterior keratometry, AL, ACD and WTW measurements for IOLMaster and ANTERION. The discrepancies between their measurements resulted in significant difference in the calculated IOL power for SRK/T, Hoffer and Holladay formulas, but not for Haigis formula.

Download Full-text