Effect of Macitentan on Long-term Outcomes in Patients With Pulmonary Arterial Hypertension (PAH): Subanalysis of SERAPHIN Comparing Incident and Prevalent Patient Populations Not Treated With Background PAH-Specific Therapy

CHEST Journal ◽  
2013 ◽  
Vol 144 (4) ◽  
pp. 876A ◽  
Author(s):  
Gùrald Simonneau ◽  
Richard Channick ◽  
Marion Delcroix ◽  
Nazzareno Galiè ◽  
Hossein Ghofrani ◽  
...  
2017 ◽  
Vol 8 (1) ◽  
pp. 204589321774805 ◽  
Author(s):  
Barbara L. LeVarge ◽  
Anica C. Law ◽  
Blanche Murphy

Infection, thrombosis, and catheter dislodgment are well-recognized potential complications of chronic intravenous prostanoid therapy for pulmonary arterial hypertension. As long-term outcomes of pulmonary hypertension patients improve, novel adverse events are likely to arise. We describe the sudden development of unexplained hypotension and lightheadedness in a patient receiving intravenous epoprostenol for several years, ultimately determined to be due to an unusual catheter complication, not previously described in this population.


PLoS ONE ◽  
2018 ◽  
Vol 13 (3) ◽  
pp. e0193226 ◽  
Author(s):  
Rogério Souza ◽  
Richard N. Channick ◽  
Marion Delcroix ◽  
Nazzareno Galiè ◽  
Hossein-Ardeschir Ghofrani ◽  
...  

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